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Original Article

Nerve Growth Factor (NGF) Responses by Non-Neuronal Cells: Detection by Assay of a Novel NGF-Activated Protein Kinase

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Pages 321-331 | Received 05 May 1989, Accepted 05 Sep 1989, Published online: 03 Aug 2009

References

  • Aletta J. M., Greene L. A. Sequential phosphorylation of chartin microtubule-associated proteins is regulated by the presence of microtubules. J. Cell Biol. 1987; 105: 277–290
  • Aletta J. M., Lewis S. A., Cowan N. J., Greene L. A. Nerve growth factor regulates both the phosphorylation and steady state levels of microtubule associated protein 1.2 (MAP 1.2). J. Cell Biol. 1988; 106: 1573–1581
  • Bradshaw R. A., Costrini N. V. The structure and function of nerve growth factor. Growth and Maturation Factors, G. Guroff. Wiley, New York 1983; 1–30
  • Blackshear P. J., Nairn A. C., Kuo J. F. Protein kinases 1988: a current prospective. FASEB J. 1988; 2: 2957–2969
  • Blenis J., Erikson R. L. The regulation of protein kinase activities in PC12 pheochromocytoma cells. EMBO J. 1986; 5: 3441–3447
  • Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976; 72: 248–252
  • Bothwell M. A., Schechter A. L., Vaughn K. M. Clonal variants of PC12 pheochromocytoma cells with altered responses to NGF. Cell 1980; 21: 857–861
  • Cremins J., Wagner J. A., Halegoua S. Nerve growth factor action is mediated by cyclic AMP and Ca–/ phospholipid-dependent protein kinase. J. Cell Biol. 1986; 103: 887–893
  • Dickson J. G., Prentice H., Julien J. P., Ferrari G., Leon A., Walsh F. S. Nerve growth factor activates thy-1 and neurofilament gene transcription in rat PC12 cells. EMBO J. 1986; 5: 3449–3453
  • End D., Tolson N., Hashimoto S., Guroff G. Nerve growth factor-induced decrease in the cell-free phosphorylation of a soluble protein in PC12 cells. J. Biol. Chem. 1983; 258: 6549–6555
  • Fabricant R. N., DeLarco J. E., Todaro G. J. Nerve growth factor receptors on human melanoma cells in culture. Proc. Natl. Acad. Sci. USA 1977; 74: 565–569
  • Green S. H., Greene L. A. A single M ∼ 103.000 125I-β-nerve growth factor-affinity-labeled species represents both the low and high affinity forms of the nerve growth factor receptor. J. Biol. Chem. 1986; 261: 15316–15326
  • Green S. H., Rydel R. E., Connolly J. L., Greene L. A. PC12 cells mutant that possess low- but not high-affinity nerve growth factor receptors neither respond to nor internalize nerve growth factor. J. Cell Biol. 1986; 102: 830–843
  • Greenberg M. E., Greene L. A., Ziff E. B. Nerve growth factor and epidermal growth factor induced rapid transient changes in proto-oncogene transcription in PC12 cells. J. Biol. Chem. 1985; 260: 14101–14110
  • Greene L. A. Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium. J. Cell Biol. 1978; 78: 747–755
  • Greene L. A., McGuire J. C. Induction of ornithine decarboxylase by nerve growth factor dissociated from effects on survival and neurite outgrowth. Nature 1978; 276: 191–194
  • Greene L. A., Shooter E. M. The nerve growth factor: biochemistry, synthesis and mechanism of action. Annu. Rev. Neurosci. 1980; 3: 353–402
  • Greene L. A., Tischler A. S. PC12 pheochromocytoma cultures in neurobiological research. Adv. Cell. Neurobiol. 1982; 3: 373–414
  • Greene L. A., Liem R. K. H., Shelanski M. L. Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor. J. Cell Biol. 1983; 96: 76–83
  • Greene L. A., Aletta J. M., Rukenstein A., Green S. H. PC12 pheocromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation. Methods Enzymol. 1987; 147: 207–217
  • Greene L. A., Tischler A. S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 1976; 73: 2424–2428
  • Halegoua S., Patrick J. Nerve growth factor mediates phosphorylation of specific proteins. Cell 1980; 22: 571–581
  • Hama T., Huang K. P., Guroff G. Protein kinase C as a component of a nerve growth factor-sensitive phosphorylation system in PC12 cells. Proc. Natl. Acad. Sci. USA 1986; 83: 2353–2357
  • Hempstead B. L., Schleifer L. S., Chao M. V. Expression of functional nerve growth factor receptors after gene transfer. Science 1989; 243: 373–375
  • Hosang M., Shooter E. M. Molecular characteristic of nerve growth factor receptors on PC12 cells. J. Biol. Chem. 1985; 260: 655–662
  • Hunter T. A thousand and one protein kinases. Cell 1987; 50: 823–829
  • Landreth G. E., Rieser G. D. Nerve growth factor and epidermal growth factor-stimulated phosphorylation of a PC12 cytoskeletally associated protein in situ. J. Cell Biol. 1985; 100: 677–683
  • Lee K., Seeley P. J., Müller T. H., Helmer-Matyjek E., Sabban E., Goldstein M., Greene L. A. Regulation of tyrosine hydroxylase phosphorylation in PC12 pheochromocytoma cells by elevated K- and nerve growth factor: evidence for different mechanisms of action. Mol. Pharmacol. 1985; 28: 220–228
  • Levi A., Biocca S., Cattaneo A., Calissano P. The mode of action of nerve growth factor in PC12 cells. Mol. Neurobiol. 1988; 2: 201–226
  • Levi-Montalcini R. The nerve growth factor: 35 years later. EMBO J. 1987; 6: 1145–1154
  • Lord J. M., Bunce C. M., Brown G. The role of protein phosphorylation in the control of cell growth and differentiation. Br. J. Cancer. 1988; 58: 549–555
  • Maruyama K., Schiavi S. C., Huse W., Johnson G. L., Ruley E. H. myc and E1A oncogenes alter responses of PC12 cells to nerve growth factor and block differentiation. Oncogene 1987; 1: 361–367
  • Matsuda Y., Guroff G. Purification and mechanism of activation of a nerve growth factor-sensitive 56 kinase from PC12 cells. J. Biol. Chem. 1986; 262: 2832–2844
  • McGuire J. C., Greene L. A., Furano A. V. NGF stimulates incorporation of fucose or glucosamine into an external glycoprotein in cultured rat PC12 pheochromocvtoma cells. Cell 1978; 15: 357–365
  • Nakanishi N., Guroff G. Nerve growth factor-induced increase in the cell-free phosphorylation of a nuclear protein in PC12 cells. J. Biol. Chem. 1985; 260: 7791–7799
  • Romano C., Nichols R. A., Greengard P., Greene L. A. Synapsin I in PC12 cells. I. Characterization of the phosphoprotein and effect of chronic NGF treatment. J. Neurosci 1987; 7: 1294–1299
  • Rowland E. A., Müller T. H., Goldstein M., Greene L. A. Cell-free detection and characterization of a novel nerve growth factor-associated protein kinase in PC12 cells. J. Biol. Chem. 1987; 262: 7504–7513
  • Rowland E. A., Greene L. A. Multiple pathways of N-kinase activation in PC12 cells. J. Neurochem. 1989, (in press)
  • Thomson T. M., Rettig W. J., Garin Chesa P., Green S. H., Carrato Mena A., Old L. J. Expression of human nerve growth factor receptor on cells derived from all three germ layers. Exp. Cell Res. 1988; 174: 533–539
  • Thomson T. M., Pellicer A., Greene L. A. Induction of c-fos mRNA by nerve growth factor in a Ewing's sarcoma cell line. J. Cell Physiol. 1989, (in press)
  • Togari A., Guroff G. Partial purification and characterization of a nerve growth factor-sensitive kinase and its substrate from PC12 cells. J. Biol. Chem. 1985; 260: 3804–3811
  • Volonté C., Rukenstein A., Loeb D. M., Greene L. A. Differential inhibition of NGF responses by purine analogues: correlation with inhibition of an NGF-activated protein kinase. J. Cell Biol. 1989, (in press)
  • Yankner B. A., Shooter E. M. The biology and mechanism of action of nerve growth factor. Annu. Rev. Biochem. 1982; 51: 845–868
  • Yu M. W., Tolson N. W., Guroff G. Increased phosphorylation of specific nuclear proteins in superior cervical ganglia and PC12 cells in response to nerve growth factor. J. Biol. Chem. 1980; 253: 10481–10492

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