Role of Transforming Growth Factor β in Colorectal Cancer

References

• Anzano M. A., Roberts A. B., Meyers C. A., Komoriya A., Lamb L. C., Smith J. M., Sporn M. B. Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells. Cancer Res. 1982; 42: 4776–4778
   PubMedGoogle Scholar
• Anzano M. A., Rieman D., Prichett W., Bowen-Pope D. F., Greig R. Growth factor production by human colon carcinoma cell lines. Cancer Res. 1989; 49: 2898–2904
   PubMed Web of Science ®Google Scholar
• Arteaga C. L., Coffey R. J., Jr., Dugger T. C., McCutchen C. M., Moses H. L., Lyons R. M. Growth stimulation of human breast cancer cells with anti-transforming growth factor β antibodies: evidence for negative autocrine growth regulation by transforming growth factor β. Cell Growth Differ. 1990; 1: 367–374
   PubMedGoogle Scholar
• Arteaga C. L., Tandon A. K., von Hoff D. D., Osborne C. K. Transforming growth factor β: potential autocrine inhibition of estrogen receptor-negative human breast cancer cells. Cancer Res. 1988; 48: 3898–3904
   PubMed Web of Science ®Google Scholar
• Bamard J. A., Beauchamp R. D., Coffey R. J., Moses H. L. Regulation of intestinal epithelial cell growth by transforming growth factor β. Proc. Natl Acad. Sci. USA 1989; 86: 1578–1582
   PubMedGoogle Scholar
• Boyd F. T., Massagué J. Growth inhibitory response to transforming growth factor-β linked to expression of a 53 kDa cell surface TGF-β receptor. J. Biol. Chem. 1989; 264: 2272–2278
   PubMed Web of Science ®Google Scholar
• Chakrabarty S. Role of protein kinase C in transforming growth factor-βl induction of carcinoembryonic antigen in human colon carcinoma cells. J. Cell. Physial. 1992; 152: 494–499
   PubMed Web of Science ®Google Scholar
• Chakrabarty S., Fan D., Varani J. Modulation of differentiation and proliferation in human colon carcinoma cells by transforming growth factor β1 and β2. Int. J. Cancer 1990; 46: 493–499
   PubMed Web of Science ®Google Scholar
• Chakrabarty S., Tobon A., Varani J., Brattain M. G. Induction of carcinoembryonic antigen secretion and modulation of protein secretion/expression and fibronectin/laminin expression in human colon carcinoma cells by transforming growth factor-β. Cancer Res 1988; 48: 4059–4064
   PubMed Web of Science ®Google Scholar
• Cheifetz S., Hernandez H., Laiho M., ten Dijke P., Iwata K. K., Massague J. Distinct transforming growth factor-β receptor subsets as determinants of cellular responsiveness to three TGF-β isoforms. J. Bid. Chem. 1990; 265: 20533–20538
   PubMed Web of Science ®Google Scholar
• Coffey R. J., Jr., Goustin A. S., Mangelsdorf Soderquist A., Shipley G. D., Wolfshohl J., Carpenter G., Moses H. L. Transforming growth factor α and β expression in human colon cancer lines: implications for an autocrine model. Cancer Res. 1987; 47: 4590–4594
   PubMed Web of Science ®Google Scholar
• Coffey R. J., Jr., Shipley G. D., Moses H. L. Production of transforming growth factors by human colon cancer lines. Cancer Res. 1986; 46: 1164–1169
   PubMed Web of Science ®Google Scholar
• Collins J. F., Herman P., Schuch C., Bagby G. C., Jr. c-myc antisense oligonucleotides inhibit the colony-forming capacity of Colo 320 colonic carcinoma cells. J. Clin. Invest. 1992; 89: 1523–1527
   PubMed Web of Science ®Google Scholar
• Fan D., Chakrabarty S., Seid C., Bell C. W., Schackert H., Morikawa K., Fidler I. J. Clonal stimulation of human colon carcinomas and human renal carcinomas mediated by transforming growth factor beta 1. Cancer Commun. 1989; 1: 117–125
   PubMedGoogle Scholar
• Filmus J., Zhao J., Buick R. N. Overexpression of H-ras oncogene induces resistance to growth-inhibitory action of transforming growth factor beta-I (TGF-βl) and alters the number and type of TGF-βI receptors in rat intestinal epithelial cell clones. Oncogene 1992; 7: 521–526
   PubMedGoogle Scholar
• Forgue-Lafitte M.-E., Coudray A.-M., Breant B., Mester J. Proliferation of the human colon carcinoma cell line HT29: autocrine growth and deregulated expression of the c-myc oncogene. Cancer Res. 1989; 49: 6566–6571
   PubMed Web of Science ®Google Scholar
• Geiser A. G., Burmester J. K., Webbink R., Roberts A. M., Spom M. B. Inhibition of growth by transforming growth factor-β following fusion of two nonresponsive human carcinoma cell lines. J. Biol. Chem. 1992; 267: 2588–2593
   PubMed Web of Science ®Google Scholar
• Glick A. B., McCune B. K., Abdulkarem N., Flanders K. C., Lumadue J. A., Smith J. M., Spom M. B. Complex regulation of TGFβ expression by retinoic acid in the vitamin A-deficient raf. Development 1991; 111: 1081–1086
   PubMed Web of Science ®Google Scholar
• Graycar J. L., Miller D. A., Amck B. A., Lyons R. M., Moses H. M., Derynck R. Human transforming growth factor-β3: recombinant expression, purification, and biological activities in comparison with transforming growth factors-β1 and β2. Mol. Endocrinol. 1989; 3: 1977–1986
   PubMed Web of Science ®Google Scholar
• Hafez M. M., Infante D., Winawer S., Friedman E. Transforming growth factor-β1, acts as an. autoaine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation. Cell Growth Differ. 1990; 1: 617–626
   PubMedGoogle Scholar
• Hoosein N. M., McKnight M. K., Levine A. E., Mulder K. M., Childress, Brattain K. E. D. E., Brattain M. G. Differential sensitivity of subclasses of human colon carcinoma cell lines to the growth inhibitory effects of transforming growth factor-β1. Exp. Cell Res. 1989; 181: 442–453
   PubMed Web of Science ®Google Scholar
• Hoosein N. M., Brattain D. E., McKnight M. K., Levine A. E., Brattain M. G. Characterization of the inhibitory effects of transforming growth factor-β on a human colon carcinoma cell line. Cancer Res. 1987; 47: 2950–2954
   PubMedGoogle Scholar
• Howe P. H., Leof E. B. Transforming growth factor β1 treatment of AKR-2B cells is coupled through a pertussis-toxin-sensitive G-protein(s). Biochem. J. 1989; 261: 879–886
   PubMed Web of Science ®Google Scholar
• Howe P. H., Bascom C. C., Cunningham M. R., Leof E. B. Regulation of transforming growth factor β1 action by multiple transducing pathways: evidence for both G protein-dependent and -independent signaling. Cancer Res. 1989; 49: 6024–6031
   PubMed Web of Science ®Google Scholar
• Kimchi A., Wang X.-F., Weinberg R. A., Cheifetz S., Massague J. Absence of TGF-β receptors and growth inhibitory responses in retinoblastoma cells. Science 1988; 240: 196–198
   PubMed Web of Science ®Google Scholar
• Lahm H., Petral-Malec D., Yilmaz-Ceyhan A., Fischer J. R., Lorenzoni M., Givel J.-C., Odartchenko N. Growth stimulation of a human colorectal carcinoma cell line by interleukin-1 and -6 and antagonistic effects of transforming growth factor βI. Eur. J. Cancer 1992; 28A: 1894–1899
   PubMed Web of Science ®Google Scholar
• Laiho M., Weis F. M. B., Boyd F. T., Ignotz R. A., Massagué J. Responsiveness to transforming growth factor-β restored by complementation between cells defective in TGF-β receptors I and II. J. Biol. Chem. 1991; 266: 9108–9112
   Google Scholar
• Laiho M., Weis F. M. B., Massagué J. Conconmitant loss of transforming growth factor (TGF)-β receptor types I and II in TGF-β resistant cell mutants implicates both receptor types in signaltransduction. J. Biol. Chem. 1990; 265: 18518–18524
   PubMed Web of Science ®Google Scholar
• Lin H. Y., Wang X.-F., Ng-Eaton E., Weinberg R. A., Lodish H. F. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell 1992; 68: 775–785
   PubMed Web of Science ®Google Scholar
• Lopez-Casillas F., Cheifetz S., Doody J., Andres J. L., Lane W. S., Massagué J. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system. Cell 1991; 67: 785–795
   PubMed Web of Science ®Google Scholar
• Manning A. M., Williams A. C., Game S. M., Paraskeva C. Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor β (TGF-β): conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-β. Oncogene 1991; 6: 1471–1476
   PubMed Web of Science ®Google Scholar
• Marshall C. J. Tumor suppressor genes. Cell 1991; 64: 313–326
   PubMed Web of Science ®Google Scholar
• Massagué J. Receptors for the TGF-β family. Cell 1992; 69: 1067–1070
   PubMed Web of Science ®Google Scholar
• Massagué J. The transforming growth factor-β family. Annu. Rev. Cell Bid. 1990; 6: 597–641
   PubMedGoogle Scholar
• Meager A. Assays for transforming growth factor β. J. Immunol. Meth. 1991; 141: 1–14
   PubMed Web of Science ®Google Scholar
• Moses H. L., Yang E. Y., Pietenpol J. A. TGF-β stimulation and inhibition of cell proliferation; new mechanistic insights. Cell 1990; 63: 245–247
   PubMed Web of Science ®Google Scholar
• Mulder K. M., Zhong Q., Choi H. G., Humphrey L. E., Brattain M. G. Inhibitory effects of transforming growth factor β1 on mitogenic response, transforming growth factor α, and c-myc in quiescent, well-differentiated colon carcinoma cells. Cancer Res. 1990; 50: 7581–7586
   PubMedGoogle Scholar
• Mulder K. M., Ramey M. K., Hoosein N. M., Levine A. E., Hinshaw X. H., Brattain D. E., Brattain M. G. Characterization of transforming growth factor-β-resistant sub-clones isolated from a transforming growth factor-β-sensitive human colon carcinoma cell line. Cancer Res. 1988a; 48: 7120–7125
   PubMedGoogle Scholar
• Mulder K. M., Levine A. E., Hernandez X., McKnight M. K., Brattain D. E., Brattain M. G. Modulation of c-myc by transforming growth factor-β in human colon carcinoma cells. Biochem. Biophys. Res. Commun. 1988b; 150: 711–716
   PubMedGoogle Scholar
• Mulder K. M., Brattain M. G. Alterations in c-myc expression in relation to maturational status of human colon carcinoma cells. Int. J. Cancer 1988; 42: 64–70
   PubMedGoogle Scholar
• Murthy U., Anzano M. A., Greig R. G. Expression of TGF-α/EGF and TGF-β receptors in human colon carcinoma cell lines. Znt. J. Cancer 1989; 44: 110–115
   PubMedGoogle Scholar
• Murthy U. S., Anzano M. A., Stadel J. M., Greig R. Coupling of TGF-β-induced mitogenesis to G-protein activation in AKR-2B cells. Biochem. Blophys. Res. Commun. 1988; 152: 1228–1235
   PubMed Web of Science ®Google Scholar
• Pignatelli M., Bodmer W. F. lntegrin-receptor-mediated differentiation and growth inhibition are enhanced by transforming growth factor-β in colorectal tumour cells grown in collagen gel. Int. J. Cancer 1989; 44: 518–523
   PubMedGoogle Scholar
• Roberts A. B., Sporn M. B. The transforming growth factor-betas. Handbook of Experimental Pharmacology: Peptide Growth Factors and Their Receptors I, M. B. Spom, A. B. Roberts. Springer Verlag, HeidelbergGermany 1990; Vol. 95: 419–472
   Google Scholar
• Roberts A. B., Anzano M. A., Lamb L. C., Smith J. M., Spom M. B. New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues. Proc. Natl Acad. Sci. USA 1981; 78: 5339–5343
   PubMed Web of Science ®Google Scholar
• Schroy P., Rifkin J., Coffey R. J., Winawer S., Friedman E. Role of transforming growth factor β1 in induction of colon carcinoma differentiation by hexamethylene bisacetamide. Cancer Res. 1990; 50: 261–265
   PubMedGoogle Scholar
• Shull M. M., Ormsby I., Kier A. B., Pawlowski S., Diebold R. J., Yin M., Allen R., Sidman C., Proetzel G., Calvin D., Annunziata N., Doetschman T. Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 1992; 359: 693–699
   PubMed Web of Science ®Google Scholar
• Spom M. B., Roberts A. 8. Autocrine growth factors and cancer. Nature 1985; 318: 745–747
   Google Scholar
• Spom M. B., Roberts A. B., Wakefield L. M., Assoian R. K. Transforming growth factor-β: Biological function and chemical structure. Science 1986; 233: 532–534
   PubMedGoogle Scholar
• Suardet L., Gaide A.-C., Calmes J.-M., Sordat B., Givel J.-C., Eliason J. F., Odartchenko N. Responsiveness of three newly established human colorectal cancer cell lines to transforming growth factors β1 and β2. Cancer Res. 1992; 52: 3705–3712
   PubMed Web of Science ®Google Scholar
• Tucker R. F., Volkenant M. E., Branum E. L., Moses H. L. Comparison of intra- and extracellular transforming growth factors from nontransformed and chemically transformed mouse embryo cells. Cancer Res. 1983; 43: 1581–1586
   PubMedGoogle Scholar
• Wakefield L. M., Smith D. M., Masui T. M., Hams C. C., Spom M. B. Distribution and modulation of the cellular receptor for transforming growth factor-beta. J. Cell Bid. 1987; 105: 965–975
   PubMed Web of Science ®Google Scholar
• Wang X.-F., Lin H. Y., Ng-Eaton E., Downward J., Lodish H. F., Weinberg R. A. Expression cloning and characterization of the TGF-β type III receptor. Cell 1991; 67: 797–805
   PubMed Web of Science ®Google Scholar
• Williams A. C., Harper S. J., Paraskeva C. Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence. Cancer Res. 1990; 50: 4724–4730
   PubMedGoogle Scholar
• Wu S., Theodorescu D., Kerbel R. S., Willson J. K. V., Mulder K. M., Humphrey L. E., Brattain M. G. TGF-β1, is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector. J. Cell Bid. 1992; 116: 187–196
   PubMed Web of Science ®Google Scholar
• Yan Z., Hsu S., Winawer S., Friedman E. Transforming growth factor β1 (TGF-β1) inhibits retinoblastoma gene expression but not pRB phosphorylation in TGF-β1-growth stimulated colon carcinoma cells. Oncogene 1992; 7: 801–805
   PubMed Web of Science ®Google Scholar
• Zugmaier G., Ennis B. W., Deschauer B., Katz D., Knabbe C., Wilding G., Daly P., Jippman M. E., Dickson R. B. Transforming growth factors type β1, and β2 are equipotent growth inhibitors of human breast cancer cell lines. J. Cell. Physiol. 1989; 141: 353–361
   PubMed Web of Science ®Google Scholar