Restrictin-P/Stromal Activin A, Kills its Target Cells Via an Apoptotic Mechanism

References

• Aggarwal B. B., Kohr W. J., Hass P. E., Moffat B., Spencer S. A., Henzel W. J., Bringman T. S., Nedwin G. E., Goeddel D. V., Harkins R. N. Human tumor necrosis factor; production, purification, and characterization. J. Biol. Chem. 1985; 260: 2345–2354
   PubMed Web of Science ®Google Scholar
• Bissonnette R. P., Echeverri F., Mahboubi A., Green D. R. Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature 1992; 359: 552–554
   PubMed Web of Science ®Google Scholar
• Brosh N., Sternberg D., Honigwachs-Sha'anani J., Lee B-C, Shav-Tal Y., Tzehoval E., Shulman L., Toledo J., Hacham J., Carmi P., Jiang W., Horn F., Burstein Y., Zipori D. The plasmacytoma growth inhibitor restrictin-P is an antagonist of interleukin-6 and interleukin-11: identification as a stroma derived activin A, in press
   Google Scholar
• Carson D. A., Ribeiro J. M. Apoptosis and Disease. The lancet 1993; 341: 1251–1254
   PubMed Web of Science ®Google Scholar
• De Kretser D. M., Robertson D. M. The isolation and physiology of inhibin and related proteins. Biol. Reprod. 1989; 40: 33–47
   PubMed Web of Science ®Google Scholar
• Duvall E., Wyllie A. H. Death and the cell. Immunology Today 1986; 7: 115–119
   PubMedGoogle Scholar
• Ellis H. M., Horvitz H. R. Genetic control of programmed cell death in the nematode C. elegans. Cell 1986; 44: 817–829
   PubMed Web of Science ®Google Scholar
• Goeddel D. V., Aggawal B. B., Gray P. W., Leung D. W., Nedwin G. E., Palladino M. A., Patton J. S., Pennica D., Shepard H. M., Surarman B. J., Wong G. H. W. Tumor necrosis factor, gene structure and biological activities. Cold Spring Harbor Symposia on Quantitative Biology 1986; 11: 597–609
   Google Scholar
• Graham G. J., Wright E. G., Hewick R., Wolpe S. D., Wilkie N. M., Donaldson D., Lorimore S., Pragnell L B. Identification and characterization of an inhibitor of haemopoietic stem cell proliferation. Nature 1990; 344: 442–444
   PubMed Web of Science ®Google Scholar
• Honigwachs-Sha'anani J., Brosh N., Kompier R., Kadouri A., Zipori D. Restrictin-P: the first member of a putative family of novel inhibitors. Ann. NY Acad. Sci. 1991; 628: 287–297
   Google Scholar
• Hunter T. Braking the cycle. Cell 1993; 75: 839–841
   PubMed Web of Science ®Google Scholar
• Kadouri A., Kompier R., Honigwachs-Sha'anani J., Toledo J., Brosh N., Sternberg D., Levy A., Tzehoval E., Zipori D. Dynamic changes in cytokine secretion by stromal cells during prolonged maintenance under protein-free conditions. International J. Cell Cloning 1992; 10: 299–308
   Google Scholar
• Larrick J. W., Wright S C. Cytotoxic mechanism of tumor necrosis factor-α. FASEB J. 1990; 4: 3215–3223
   PubMed Web of Science ®Google Scholar
• Lenfant M, Wdzieczak-Bakala J., Guittet E., Prome J.-C, Sotly D., Frindel E. Inhibitor of hematopoietic pluripotent stem cell proliferation: Purification and determination of its structure. Proc. Natl Acad. Sci. USA 1989; 86: 779–782
   PubMed Web of Science ®Google Scholar
• Ling N., Ueno N., Ying S.-Y., Esch F., Shimasaki S., Hotta M., Cuevas P., Guillemin R. Inhibins and activins. Vitam. Horm. 1988; 44: 1–46
   Google Scholar
• Murata M., Eto Y., Shibai H., Sakai M., Muramatsu M. Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin βA chain. Proc. Natl Acad. Sci. USA 1988; 85: 2434–2438
   PubMed Web of Science ®Google Scholar
• Nishihara T., Okahashi N., Ueda N. Activin A induces apoptotic cell death. Biochem. Biophys. Res. Commun. 1993; 197: 985–991
   Google Scholar
• Perreault J., Lemieux R. Rapid apoptotic cell death of B-cell hymbridomas in absence of gene expression. J. Cell. Physiol. 1993; 156: 286–293
   PubMed Web of Science ®Google Scholar
• Pierce G. B., Lewellyn A. L., Parchment R. E. Mechanism of programmed cell death in blastocyst. Proc. Natl Acad. Sci. USA 1989; 86: 3654–3658
   PubMed Web of Science ®Google Scholar
• Rottello R. J., Lieberman R. C., Purchio A. F., Gerschenson L. E. Coordinated regulation of apoptosis and cell proliferation by transforming growth factor β1 in cultured uterine epithelial cells. Proc. Natl Acad. Sci. USA 1991; 88: 3412–3415
   Google Scholar
• Ruff M. R., Gifford G. E. Rabbit tumor necrosis factor: mechanism of action. Infect. and Immun. 1981; 31: 380–385
   PubMed Web of Science ®Google Scholar
• Shi Y., Beni M. S., Green D. R. Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. Nature 1989; 339: 625–626
   PubMed Web of Science ®Google Scholar
• Shiozaki M., Shioya S., Izawa M., Eto Y., Shibai H. Differentiation-inducing and growth-inhibitory activities of erythroid differentiation factor (EDF/activin A) toward mouse erythorleukemic cells in vivo. Int. J. Cancer 1990; 45: 719–723
   Google Scholar
• Smith C. A., Williams C. G., Kingston R., Jenkinson E. J., Owen J. J. T. Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 1989; 337: 181–184
   PubMed Web of Science ®Google Scholar
• Vale W., Rivier J., Vaughan J., McClintock R., Corrigan A., Woo W., Karr D., Spiess J. Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid. Nature 1986; 321: 776–779
   PubMed Web of Science ®Google Scholar
• Warren D. J., Slordal L., Moore M. A. S. Tumornecrosis factor induces cell cycle arrest in multipotential hematopoietic pluripotent stem cell: a possible radioprotective mechanism. Eur. J. Haematol. 1990; 45: 158–163
   PubMed Web of Science ®Google Scholar
• White E. Death-defying acts: a meeting review on apoptosis. Genes Dev. 1993; 7: 2277–2284
   PubMed Web of Science ®Google Scholar
• Williams G. T., Smith C. A., Spooncer E., Dexter T. M., Taylor D. R. Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 1990; 343: 76–79
   PubMed Web of Science ®Google Scholar
• Yonish-Rouach E., Resnitzky D., Lotem J., Sachs L., Kimchi A., Oren M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 1991; 352: 345–347
   PubMed Web of Science ®Google Scholar
• Yu J., Shao L.-E., Lemas V., Yu A. L., Vaughan J., Rivier J., Vale W. Importance of FSH-releasing protein and inhibin in erythroid differention. Nature 1987; 330: 765–767
   PubMed Web of Science ®Google Scholar
• Zipori D. In vitro proliferation of mouse lymphoblastoid cell lines: Growth modulation by various populations of adherent cells. Cell Tissue Kinet. 1980; 13: 287–298
   Google Scholar
• Zipori D. Conditions required for the inhibition of in vitro growth of a mouse myeloma cell line by adherent bone marrow cell. Cell Tissue Kinet. 1981; 14: 479–488
   Google Scholar
• Zipori D. Regulation of hemopoiesis by cytokines that restrict options for growth and differentiation. Cancer Cells 1990; 2: 206
   Google Scholar
• Zipori D. The renewal and differentiation of hemopoietic stem cells. FASEB J. 1992; 6: 2691–2697
   Google Scholar
• Zipori D., Friedman A., Tamir M., Silverberg D., Malik Z. Cultured mouse marrow stromal cell lines. Interactions between fibroblastoid cells and monocytes. J. Cell. Physiol. 1984; 118: 143–152
   PubMed Web of Science ®Google Scholar
• Zipori D., Honigwachs-Sha'anani J. Growth restrictions in the regulation of haemopoiesis. Bailliere's Clinical Haematology 1992; 5: 741–752
   Google Scholar
• Zipori D., Tamir M., Toledo J., Oren T. Differentiation stage and lineage-specific inhibitor from the stroma of mouse bone marrow that restricts lymphoma cell growth. Proc. Natl Acad. Sci. USA 1986; 83: 4547–4551
   Google Scholar
• Zipori D., Kalai M., Tamir M. Restrictins: Stromal cell associated factors that control cell organization in hemopoietic tissues. Nat. Immun. Cell Growth Regul. 1988; 7: 185–192
   Google Scholar