21
Views
5
CrossRef citations to date
0
Altmetric
Original Article

CSF-1 and Interferon-γ Act Synergistically to Promote Differentiation of FDC-P1 Cells into Macrophages

, , , , &
Pages 159-171 | Received 21 Aug 1997, Accepted 01 Oct 1997, Published online: 21 Aug 2009

References

  • Alexander W. S., Maurer A., Novak U., Harrison-Smith M. Tyrosine-599 of the c-Mpl receptor is required for She phosphorylation and the induction of cellular differentiation. EMBOJ. 1996; 15: 6531–6541
  • Alonso G., Koegl M., Mazurenko N., Courtneidge S. A. Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors. J. Biol. Chem. 1995; 270: 9840–9848
  • Barahmoud-Pour F., Meinke A., Eilers A., Gouilleux F., Groner B., Decker T. Colony-stimulating factors and interferon-γ activate a protein related to MGF-Stat5 to cause formation of the differentiation-induced factor in myeloid cells. FEBS Lett. 1995; 360: 29–33
  • Bourette R. P., Myles G. M., Carlberg K., Chen A. R., Rohrschneider L. R. Uncoupling of proliferation and differentiation signals mediated by the murine macrophage colony-stimulating factor receptor expressed in myeloid FDC-Pl cells. Cell Growth and Diff. 1995; 6: 631–645
  • Bourette R. P., Myles G. M., Choi J.-L., Rohrschneider L. R. Sequential activation of phosphatidylinositol 3-kinase and phospolipase Cγ2 by the M-CSF receptor is necessary for differentiation signalling. EMBO J. 1997; 16: 5880–5893
  • Buscher D., Sbarba P. D., Hipskind R. A., Rapp U. R., Stanley E. R., Baccarini M. v-Raf confers CSF-1 independent growth to a macrophage cell line and leads to immediate early gene expression without MAP-kinase activation. Oncogene 1993; 8: 3323–3332
  • Caldenhoven E., van Dijk T. B., Solari R., Armstrong J., Raaijmakers J. A. M., Lammers J. W. J., Koenderman L., de Gro to R. P. STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription. J. Biol. Chem. 1996; 271: 13221–13227
  • Carlberg K., Rohrschneider L. R. The effect of activating mutations on dimerization, tyrosine phosphorylation, and internalization of the macrophage colony-stimulating factor receptor. Mol. Biol. Cell. 1994; 5: 81–95
  • Chakraborty A., White S. M., Schaefer T. S., Ball E. D., Dyer K. F., Tweardy D. J. Granulocyte colony-stimulating factor activation of Stat3α and Stat3yβ in immature normal and leukemic human myeloid cells. Blood 1996; 88: 2442–2449
  • David M., Grimley P. M., Finbloom D., Lamer A. C. A nuclear tyrosine phosphatase downregulates interferon-induced gene expression. Mol. Cell. Biol. 1993; 13: 7515–7521
  • Durbin J. E., Hackenmiller R., Simon M. C., Levy D. E. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 1996; 84: 443–450
  • Gough N. M., Williams R. L. The pleiotropic actions of leukemia inhibitory factor. Cancer Cells 1989; 1: 77–80
  • Haspel R. L., Salditt-Georgieff M., Darnell J. E. The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. EMBO J. 1996; 15: 6262–6268
  • Hirano T., Kishimoto T. Interleukin-6. Peptide growth factors and their receptors 1, M. B. Sporn, A. B. Roberts. Springer, Berlin 1990; 633–665
  • Igarashi K., Garotta G., Ozmen L., Ziemiecki A., Wilks A. F., Harpur A. G., Lamer A. C., Finbloom D. S. Interferon-γ induces tyrosine phosphorylation of interferon-γ receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor. J. Biol. Chem. 1994; 269: 14333–14336
  • Joos H., Trouliaris S., Helftenbein G., Nieman H., Ta-Mura T. Tyrosine phosphorylation of the juxtamem-brane domain of the v-Fms oncogene product is required for its association with a 55-kDa protein. J. Biol. Chem 1996; 271: 24476–24481
  • Kaushansky K. The mpl ligand: molecular and cellular biology of the critical regulator of megakaryocyte development. Stem Cells (Dayt) 1994; 12(Suppl 1)91–97
  • Koury M. J., Bondurant M. C. The molecular mechanism of erythropoietin action. Eur. J. Biochem. 1992; 210: 649–663
  • Li W., Stanley E. R. Role of dimerization of the CSF-1 receptor in its activation and internalization during the CSF-1 response. EMBO J. 1991; 10: 277–288
  • Lioubin M. N., Myles G. M., Carlberg K., Bowtell D., Rohrschneider L. R. She, Grb2, Sos1 and a 150-kilo-dalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cells. Mol. Cell. Biol. 1994; 14: 5682–5691
  • Meraz M. A., White J. M., Sheehan K. C., Bach E. A., Rodig S. J., Dighe A. S., Kaplan D. H., Riley J. K., Green-Lund A. C., Campbell D., Carver-Moore K., DuBois R. N., Clark R., Aguet M., Schreiber R. D. Targeted disruption of the Stat1 gene in mice reveals unexpected physiological specificity in the JAK-STAT signaling pathway. Cell 1996; 84: 431–442
  • Metcalf D. The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. Nature 1989; 339: 27–30
  • Minami M., Inoue M., Wei S., Takeda K., Matsumoto M., Kishimoto T., Akira S. STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line. Proc. Natl. Acad. Sci. USA 1996; 93: 3963–3966
  • Mizushima S., Nagata S. pEF-BOS, a powerful mammalian expression vector. Nucl. Acids Res. 1990; 18: 5322
  • Nicholson S. E., Starr R., Novak U., Hilton D. J., Lay-Ton J. E. Tyrosine residues in the granulocyte colony-stimulating factor (G-CSF) receptor mediate G-CSF-induced differentiation of murine myeloid leukemic (MI) cells. J. Biol. Chem. 1996; 271: 26947–26953
  • Novak U., Harpur A. G., Paradiso L., Kanagasundaram V., Jaworowski A., Wilks A. F., Hamilton J. A. CSF-1 induced STAT activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts. Blood 1995; 86: 2948–2956
  • Novak U., Nice E., Hamilton J. A., Paradiso L. Requirement for Y706 of the murine (or Y708 of the human) CSF-1 receptor for STAT1 activation in response to CSF-1. Oncogene 1996a; 13: 2607–2613
  • Novak U., Mui A., Miyajima A., Paradiso L. Formation of STAT5 containing DNA binding complexes in response to CSF-1 and PDGF. J. Biol. Chem. 1996b; 271: 18350–18354
  • Pixley F., Lee P. S. W., Dominguez M. G., Einstein D. B., Stanley E. R. A heteromorphic protein tyrosine phosphatase, PTP phi, is regulated by CSF-1 in macrophages. J. Biol Chem. 1995; 270: 27339–27347
  • Reedijk M., Liu X., Van der Geer P., Letwin K., Water-Field M. D., Hunter T., Pawson T. Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI3-kinase SH2 domains: a model for SH2-mediated receptor-target interactions. EMBO J. 1992; 11: 1365–1372
  • Rohrschneider L. R., Metcalf D. Induction of macrophage colony stimulating factor-dependent growth and differentiation after introduction of the murine c-fms gene into FDC-P1 cells. Mol. Cell Biol. 1989; 9: 5081–5092
  • Roussel M. F., Shurtleff S. A., Downing J. R., Sherr C. J. A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidyli-nositol 3-kinase, or induction of c-fos and junB genes. Proc. Natl. Acad. Sci. USA 1990; 87: 6738–6742
  • Schaefer T. S., Sanders L. K., Nathans D. Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3. Proc. Natl Acad. Sci. USA 1995; 92: 9097–9101
  • Shuai K., Schindler C., Prezioso V. R., Darnell J. E. Activation of transcription by IFN-Γ: tyrosine phosphorylation of a 91 kDa DNA binding protein. Science 1992; 261: 1736–1739
  • Stanley E. R., Guilbert L. J., Tushinski R. J., Bartelmez S. H. CSF-1: a mononuclear phagocyte lineage-specific hemopoietic growth factor. J. Cell. Biochem. 1983; 21: 151–159
  • Vadiveloo P. K., Vairo G., Novak U., Royston A. K., Whit-Ty G., Filonzi E. L., Cragoe E. J., Hamilton J. A. Differential regulation of cell cycle machinery by various antiproliferative agents is linked to macrophage arrest at distinct G1 checkpoints. Oncogene 1996; 13: 599–608
  • Van der Geer P., Hunter T. Mutation of Tyr697, a Grb2-binding site, and Tyr721, a PI3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts. EMBO J. 1993; 12: 5161–5172
  • Wagner B. J., Hayes T. E., Hoban C. J., Cochran B. H. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J. 1990; 9: 4477–4484
  • Xu J., Kim S., Rockow S., Yi S. E., Wagner A. J., Hay N., Weichselbaum P. R., Li W. Blockage of early events in mitotic signaling by interferon-γ in macrophages in response to colony-stimulating factor-1. Blood 1995; 86: 2774–2788
  • Yamanaka Y., Nakajima K., Fukada T., Hibi M., Hirano T. Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation. EMBO J. 1996; 15: 1557–1565
  • Yoshikawa A., Murakami H., Nagata S. Distinct signal transduction through the tyrosine-containing domains of the granulocyte colony-stimulating factor receptor. EMBO J. 1995; 14: 5288–5296
  • Wen Z., Zhong Z., Darnell J. E. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 1995; 82: 241–250
  • Zhang X., Blenis J., Li H. C., Schindler C., Cheng-Kiang K. Requirement of serine phosphorylation for formation of STAT-promoter complexes. Science 1995; 267: 1990–1994
  • Zhong Z., Wen Z., Darnell J. E. Stat3 and Stat4: members of the family of signal transducers and activators of transcription. Proc. Natl Acad. Sci. 1994; 91: 4806–4810

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.