Insulin-like growth factor-I (IGF-I) Stimulates regrowth of the damaged intestine in rats, when administered following, but not concurrent with, methotrexate

References

• Bastian S. E. P., Walton P. E., Wallace J. C., Ballard F. J. Plasma clearance and tissue distribution of labelled insulin-like growth factor-I (IGF-I) and an analogue LR3IGF-I in pregnant rats. J. Endocrinol. 1993; 138: 327–336
   PubMed Web of Science ®Google Scholar
• Baxter R. C., Martin J. L. Binding proteins for the insulin-like growth factors, structure, regulation and function. Prog. Growth Factor Res 1989a; 1: 49–68
   PubMedGoogle Scholar
• Baxter R. C., Martin J. L. Structure of the M1, 140,000 growth hormone-dependent insulin-like growth factor binding protein complex determination by reconstitution and affinity labelling. Proc. Nat. Acad. Sci. USA 1989b; 86: 6898–6902
   PubMed Web of Science ®Google Scholar
• Corazza G. R., Frazzoni M., Dixon M. F., Gasbarrini G. Quantitative assessment of the mucosal architecture of jejunal biopsy specimens: comparison between linear measurement, stereology, and computer aided microscopy. J. Clin. Pathol. 1985; 8: 765–770
   Google Scholar
• Davies S. C., Wass J. A. H., Ross R. J. M., Cotterill A. M., Buchanan C. R., Coulson V. J., Holly J. M. P. The induction of a specific protease for insulin-like growth factor binding protein-3 in the circulation during severe illness. J. Endocrinol. 1991; 130: 469–473
   PubMed Web of Science ®Google Scholar
• Hirano M., Iwakiri R., Fujimoto K., Sakata H., Ohyama T., Sakai T., Joh T., Itch M. Epidermal growth factor enhances repair of rat intestinal mucosa damaged by oral administration of methotrexate. J. Gastroenterology 1995; 30(2)169–176
   Google Scholar
• Hossenlopp P., Segovia B., Lassarre C., Roghani M., Bredon M., Bonoux M. Evidence of enzymatic degradation of insulin-like growth factor binding proteins in the 150K complex during pregnancy. J Clin. Endocrinol. Metab 1990; 71: 797–805
   PubMed Web of Science ®Google Scholar
• Howarth G. S., Francis G. L., Cool J. C., Xu X., Byard R. W., Read L. C. Milk growth factors enriched from cheese whey ameliorate intestinal damage by methotrexate when administered orally to rats. J. Nutrition 1996; 126(10)2519–2530
   PubMed Web of Science ®Google Scholar
• Jolivet J., Cowan J. H., Curt G. A., Clendennin N. J., Charner B. A. The pharmacology and clinical use of methotrexate. N. Engl. J. Med. 1983; 309: 1094–1104
   PubMed Web of Science ®Google Scholar
• Lemmey A. B., Martin A. A., Read L. C., Tomas F. M., Owens P. C., Ballard F. J. IGF-1 and the truncated analogue des-(1–3) IGF-I enhance growth in rats after gut resection. Am J Physiol. 1991; 260: E213–219
   PubMedGoogle Scholar
• McCormack E. S., Borzillo G. V., Ambrosino C., Mak G., Hamablet L., Qu G. Y., Haley J. D. Transforming growth factor-beta 3 protection of epithelial cells from cycle-selective chemotherapy in vitro. Biochem-Pharmacol. 1997; 53(8)1149–1159
   Google Scholar
• Owens P. C., Johnson R. J., Campbell R. G., Ballard F. J. Growth hormone increases insulin-like growth factor-I (IGF-I) and decreases IGF-II in plasma of growing pigs. J. Endocrinol. 1990; 124: 269–275
   PubMed Web of Science ®Google Scholar
• Petschow B. W., Carter D. L., Hutton G. D. Influence of orally administered epidermal growth factor on normal and damaged intestinal mucosa in rats. J. Pediatric. Gastroent. Nutr 1993; 17: 49–58
   PubMedGoogle Scholar
• Read L. C., Tomas F. M., Howarth G. S., Martin A. A., Edson K. J., Gillespie C. M., Ballard F. J. Insulin-like growth factor-1 and its N-terminal modified analogues induce gut growth in dexamethasone-treated rats. J. Endocrinol 1992; 133(3)421–431
   Google Scholar
• Saxena S. K., Thompson J. S., Sharp J. G. Role of epidermal growth factor in intestinal regeneration. Surgery 1992; 111: 318–325
   PubMed Web of Science ®Google Scholar
• Sonis S. T., Costa J. W., Jr, Evitts S. M., Lindquist L. E., Nicholson M. Effect of epidermal growth factor on ulcerative mucositis in hamsters that receive chemotherapy. Oral Surg. Oral Med. Oral Pathol 1992; 74: 749–755
   PubMedGoogle Scholar
• Sonis S. T., Lindquist L., Van-Vugt A., Stewart A. A., Stam K., Qu G. Y., Iwata K. K., Haley J. D. Prevention of chemotherapy-induced ulcerative mucositis by transforming growth factor beta 3. Cancer Res. 1994; 54(5)1135–1138
   PubMed Web of Science ®Google Scholar
• Sonis S. T., Van-Vugt A. G., Brien J. P., Muska A. D., Bruskin A. M., Rose A., Haley J. D. Transforming growth factor-beta 3 mediated modulation of cell cycling and attenuation of 5-fluorouracil induced oral mucositis. Oral Oncol. 1997; 33(1)47–54
   PubMed Web of Science ®Google Scholar
• Steeb C.-B., Trahair J. F., Tomas F. M., Read L. C. Prolonged administration of IGF peptides enhances growth of gastrointestinal tissues in normal rats. Am. J. Physiol. 1994; 266: G1090–1098, (6 Pt 1)
   PubMed Web of Science ®Google Scholar
• Steeb C.-B., Trahair J. F., Read L. C. Administration of insulin-like growth factor-I (IGF-I) peptides for three days stimulates proliferation of the small intestinal epithelium in rats. Gut 1995; 37: 630–638
   PubMed Web of Science ®Google Scholar
• Tomas F. M., Knowles S. E., Owens P. C., Read L. C., Chandler C. S., Gargosky S. E., Ballard F. J. Increased weight gain, nitrogen retention and muscle protein synthesis following treatment of diabetic rats with insulin-like growth factor-I and des(1–3) IGF-I. Biochem. J. 1991a; 276(2)547–554
   Google Scholar
• Tomas F. M., Knowles S. E., Owens P. C., Read L. C., Chandler C. S., Gargosky S. E., Ballard F. J. Effects of full-length and truncted insulin-like growth factor-I on nitrogen balance and mudcle metabolism in nitrogen-restricted rats. J. Endocrinol 1991b; 128: 97–105
   PubMed Web of Science ®Google Scholar
• Tomas F. M., Knowles S. E., Owens P. C., Chandler C. S., Francis G. L., Read L. C., Ballard F. J. Insulin-like growth factor-1 (IGF-I) and especially variants are anabolic in dexamethasone-treated rats. J. Biochem. 1992; 282: 91–97
   Google Scholar
• Young S. C. J., Underwood L. E., Celinker A., Clemmons D. R. Effects of recombinant insulin-like growth factor-I (IGF-I) and growth hormone on serum IGF-binding proteins in calorically restricted adults. J Clin Endocrinol Metab 1992; 75: 603–608
   PubMed Web of Science ®Google Scholar
• Vanderhoof J. A., Park J. H., Mohammadpour H., Black-Wood D. Effects of dietary lipids on recovery from mucosal injury. Gastroenterology 1990; 8: 1226–1231
   Google Scholar
• Zapf J., Hauri C., Waldvagel M., Futo E., Häsler H., Binz K., Guler H. P., Schmid C., Froesch E. R. Recombinant human insulin-like growth factor I induces its own specific carrier protein in hypophysectomized and diabetic rats. Proc. Natl. Acad. Sci. U.S.A. 1989; 86: 3813–3817
   Google Scholar