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Original Article

Differential Ability of SOCS Proteins to Regulate IL-6 and CSF-1 Induced Macrophage Differentiation

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Pages 305-314 | Received 23 Oct 1998, Published online: 11 Jul 2009

References

  • Alexander W. S., Maurer A., Novak U., Harrison-Smith M. Tyrosine-599 of the c-Mpl receptor is required for She phosphorylation and the induction of cellular differentiation. EMBO J. 1996; 15: 6531–6541
  • Alonso G., Koegl M., Mazurenko N., Courtneidge S. A. Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors. J. Biol. Chem. 1995; 270: 9840–9848
  • Bourette R. P., Myles G. M., Carlberg K., Chen A. R., Rohrschneider L. R. Uncoupling of the proliferation and differentiation signals mediated by the murine macrophage colony-stimulating factor receptor expressed in myeloid FDC-P1 cells. Cell Growth Differ. 1995; 6: 631–645
  • Bourette R. P., Myles G. M., Choi J. L., Rohrschneider L. R. Sequential activation of phosphotidylinositol 3-kinase and phospholipase C-gamma2 by the M-CSF receptor is necessary for differentiation signalling. EMBO J. 1997; 16: 5880–5893
  • Chaturvedi P., Reddy M. V.R., Reddy E. P. Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation. Oncogene 1998; 16: 1749–1758
  • Cirri P., Chiarugi P., Marra F., Raugei G., Camici G., Manao G., Ramponi G. c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells. Biochem. Biophys. Res. Commun. 1997; 239: 493–497
  • Courtneidge S. A., Dhand R., Pilat D., Twamley G. M., Waterfield M. D., Roussel M. F. Activation of Src family kinases by colony stimulating factor-1 and their association with its receptor. EMBO J. 1993; 12: 943–950
  • Darnell J. E., Kerr I. M., Stark G. R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994; 264: 1415–1421
  • Endo T. A., Masuhara M., Yokouchi M., Suzuki R., Sakamoto H., Mitsui K., Matsumoto A., Tanimura S., Ohtsubo M., Misawa H., Miyazaki T., Leonor N., Taniguchi T., Komiya S., Yoshimura A. A new protein containing an SH2 domain that inhibits JAK kinases. Nature 1997; 387: 921–924
  • Hilton D. J., Richards R. T., Alexander W. S., Viney E. M., Wilson T. A., Sprigg N. S., Starr R., Nicholson S. E., Metcalf D., Nicola N. A. Twenty proteins containing a C-terminal SOCS box form five structural classes. Proc. Natl. Acad. Sci. USA 1998; 95: 114–119
  • Jaworowski A., Christy E., Yusoff P., Hamilton J. A. Differences in the kinetics of activation of protein kinases and extracellular signal-related protein kinase 1 in colony-stimulating factor-1 stimulated and lipopolysaccharide-stimulated macrophages. Biochem. J. 1996; 320: 1011–1016
  • Mancini A., Niedenthal R., Joos H., Koch A., Trouliaris S., Niemann H., Tamura T. Identification of a second Grb2 binding site in the vfms tyrosine kinase. Oncogene 1997; 15: 1565–1572
  • Matsumoto A., Masuhara M., Mitsui K., Yokouichi M., Ohtsubo M., Misawa H., Miyajima A., Yoshimura A. CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. Blood 1997; 89: 3148–3154
  • Minami M., Inoue M., Wei S., Takeda K., Matsumoto M., Kishimoto T., Akira S. STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line. Proc. Natl Acad. Sci. USA 1996; 93: 3963–3966
  • Minamoto S., Ikegame K., Ueno K., Narazaki M., Naka T., Yamamoto H., Matsumoto T., Saito H., Hosoe S., Kishimoto T. Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3. Biochem. Biophys. Res. Commun. 1997; 237: 79–83
  • Mizushima S., Nagata S. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 1990; 18: 5322
  • Naka T., Narazaki M., Hirata M., Matsumoto T., Minamoto S., Aono A., Nishimoto N., Kajita T., Kishimoto T. Structure and function of a new STAT-induced STAT inhibitor. Nature 1997; 387: 924–929
  • Nicholson S. E., Starr R., Novak U., Hilton D. J., Layton J. E. Tyrosine residues in the granulocyte colony-stimulating factor (G-CSF) receptor mediate G-CSF-induced differentiation of murine myeloid leukemic (M1) cells. J. Biol. Chem. 1996; 271: 26947–26953
  • Novak U., Harpur A. G., Paradiso L., Kanagasundaram V., Jaworowski A., Wilks A. F., Hamilton J. A. CSF-1 induced STAT activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts. Blood 1995; 86: 2948–2956
  • Novak U., Nice E., Hamilton J. A., Paradiso L. Requirement for Y706 of the murine (or Y708 of the human) CSF-1 receptor for STAT1 activation in response to CSF-1. Oncogene 1996; 13: 2607–2613
  • Novak U., Nicholson S., Bourette R. P., Rohrschneider L. R., Alexander W., Paradiso L. CSF-1 and interferon-γ act synergistically to promote differentiation of FDC-P1 cells into macrophages. Growth Factors 1998; 15: 159–171
  • Ohya K., Kajigaya S., Yamashita Y., Miyazato A., Hatake K., Miura Y., Ikeda U., Shimada K., Ozawa K., Mano H. SOCS-1/JAB/SSI-1 can bind to and suppress Tec protein-tyrosine kinase. J. Biol. Chem. 1997; 272: 27178–27182
  • Reedijk M., Liu X., van der Geer P., Letwin K., Waterfield M. D., Hunter T., Pawson T. Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3′-kinase SH2 domains: a model for SH2-mediated receptor-target interactions. EMBO J. 1992; 11: 1365–1372
  • Starr R., Wilson T. A., Viney E. M., Murray L. J.L., Rayner J. R., Jenkins B. J., Gonda T. J., Alexander W. S., Meltcalf D., Nicola N. A., Hilton D. J. A family of cytokine-inducible inhibitors of signaling. Nature 1997; 387: 917–921
  • Van der Geer P., Hunter T. Tyrosine 706 and 807 phosphorylation site mutants in the murine colony-stimulating factor-1 receptor are unaffected in their ability to bind or phosphorylate phosphatidylinositol-3 kinase but show differential defects in their ability to induce early response gene transcription. Mol. Cell. Biol. 1991; 11: 4698–4709
  • Van der Geer P., Hunter T. Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts. EMBO J. 1993; 12: 5161
  • Yamanaka Y., Nakajima K., Fukada T., Hibi M., Hirano T. Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation. EMBO J. 1996; 15: 1557–1565
  • Yoshimura A. T., Ohkubo T., Kiguchi N. A., Jenkins D. J., Gilbert N. G., Copeland T., Hara M., Miyajima A. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin-3 and erythropoietin receptors. EMBO J. 1995; 14: 2816–2826

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