Transfection efficiency of lipoplexes for site-directed delivery

References

• Branden, L. J., Mohamed, A. J., Smith, C. I. (1999). A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA. Nat Biotechnol 17:784–787.
   PubMed Web of Science ®Google Scholar
• Brunner, S., Sauer, T., Carotta, S., Cotten, M., Saltik, M., Wagner, E. (2000). Cell cycle dependence of gene transfer by lipoplex, polyplex, and recombinant adenovirus. Gene Ther 7:401–407.
   PubMed Web of Science ®Google Scholar
• Clark, P. R., Hersch, E. M. (1999). Cationic lipid-mediated gene transfer: current concepts. Curr Opin Mol Ther 1:158–176.
   PubMed Web of Science ®Google Scholar
• Cohen, R. N., van der Aa, M. A., Macaraeg, N., Lee, A. P., Szoka, F. C., Jr. (2009). Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection. J Contr Rel 135:166–174.
   PubMed Web of Science ®Google Scholar
• Dowty, M. E., Williams, P., Zhang, G., Hagstrom, J. E., Wolff, J. A. (1995). Plasmid DNA entry into postmitotic nuclei of primary rat myotubes. Proc Natl Acad Sci U S A 92:4572–4576.
   PubMed Web of Science ®Google Scholar
• El Ouahabi A., Thiry, M., Pector, V., Fuks, R., Ruysschaert, J. M., Vandenbranden, M. (1997). The role of endosome destabilizing activity in the gene transfer process mediated by cationic lipids. FEBS Lett 414:187–192.
   PubMed Web of Science ®Google Scholar
• Fang, Y., Yang, J. (1997). Two-dimensional condensation of DNA molecules on cationic lipid membranes. J Phys Chem B 101:441–449.
   Web of Science ®Google Scholar
• Farhood, H., Serbina, N., Huang, L. (1995). The role of dioleoyl phosphatidylethanolamine in cationic-liposome–mediated gene transfer. Biochim Biophys Acta 1235:289–295.
   PubMed Web of Science ®Google Scholar
• Fasbender, A., Marshall, J., Moninger, T. O., Grunst, T., Cheng, S., Welsh, M. J. (1997). Effect of co-lipids in enhancing cationic lipid-mediated gene transfer in vitro and in vivo. Gene Ther 4:716–725.
   PubMed Web of Science ®Google Scholar
• Felgner, P. L., Ringold, G. M. (1989). Cationic liposome-mediated transfection. Nature 337:387–388.
   PubMed Web of Science ®Google Scholar
• Frederik, P. M., Hubert, D. H. (2005). Cryoelectron microscopy of liposomes. Meth Enzymol 391:431–448.
   PubMed Web of Science ®Google Scholar
• Hafez, I. M., Maurer, N., Cullis, P. R. (2001). On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids. Gene Ther 8:1188–1196.
   PubMed Web of Science ®Google Scholar
• Hoekstra, D., Rejman, J., Wasungu, L., Shi, F., Zuhorn, I. (2007). Gene delivery by cationic lipids: in and out of an endosome. Biochem Soc Trans 35(Pt 1):68–71.
   PubMed Web of Science ®Google Scholar
• Jahn, A., Reiner, J. E., Vreeland, W. N., DeVoe, D. L., Locascio, L. E., Gaitan, M. (2008). Preparation of nanoparticles by continuous-flow microfluidics. J Nanopart Res 10:925–934.
   Web of Science ®Google Scholar
• Kenworthy, A. K., Hristova, K., Needham, D., McIntosh, T. J. (1995). Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol). Biophys J 68:1921–1936.
   PubMed Web of Science ®Google Scholar
• Klopfenstein, D. R., Vale, R. D., Rogers, S. L. (2000). Motor protein receptors: moonlighting on other jobs. Cell 103:537–540.
   PubMed Web of Science ®Google Scholar
• Lasic, D. (1997a). Liposomes in gene delivery. New York: CCR Press.
   Google Scholar
• Lasic, D. D. (1997b). Colloid chemistry. Liposomes within liposomes. Nature 387:26–27.
   PubMed Web of Science ®Google Scholar
• Lasic, D. D., Vallner, J. J., Working, P. K. (1999). Sterically stabilized liposomes in cancer therapy and gene delivery. Curr Opin Mol Ther 1:177–185.
   PubMed Web of Science ®Google Scholar
• Laskey, R. A. (1998). CIBA medal lecture. Regulatory roles of the nuclear membrane. Biochem Soc Trans 26:561–567.
   PubMed Web of Science ®Google Scholar
• Lechardeur, D., Lukacs, G. L. (2002). Intracellular barriers to nonviral gene transfer. Curr Gene Ther 2:183–194.
   PubMedGoogle Scholar
• Lechardeur, D., Lukacs, G. L. (2006). Nucleocytoplasmic transport of plasmid DNA: a perilous journey from the cytoplasm to the nucleus. Hum Gene Ther 17:882–889.
   PubMed Web of Science ®Google Scholar
• Lechardeur, D., Sohn, K. J., Haardt, M., Joshi, P. B., Monck, M., Graham, R. W., et al. (1999). Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer. Gene Ther 6:482–497.
   PubMed Web of Science ®Google Scholar
• Leonetti, J. P., Mechti, N., Degols, G., Gagnor, C., Lebleu, B. (1991). Intracellular distribution of microinjected antisense oligonucleotides. Proc Natl Acad Sci U S A 88:2702–2706.
   PubMed Web of Science ®Google Scholar
• Li, W., Huang, Z., MacKay, J. A., Grube, S., Szoka, F. C., Jr. (2005). Low-pH–sensitive poly(ethylene glycol) (PEG)-stabilized plasmid nanolipoparticles: effects of PEG chain length, lipid composition, and assembly conditions on gene delivery. J Gene Med 7:67–79.
   PubMed Web of Science ®Google Scholar
• Luby-Phelps, K. (2000). Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area. Int Rev Cytol 192:189–221.
   PubMed Web of Science ®Google Scholar
• Ludtke, J. J., Zhang, G., Sebestyen, M. G., Wolff, J. A. (1999). A nuclear localization signal can enhance both the nuclear transport and expression of 1-kb DNA. J Cell Sci 112( Pt 12):2033–2041.
   PubMed Web of Science ®Google Scholar
• Lukacs, G. L., Haggie, P., Seksek, O., Lechardeur, D., Freedman, N., Verkman, A. S. (2000). Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem 275:1625–1629.
   PubMed Web of Science ®Google Scholar
• Meyer, K., Uyechi, L. S., and Szoka, F. C. J. (1997). Manipulating the intracellular trafficking of nucleic acids. New York, Marcel Dekker Inc.
   Google Scholar
• Needham, D., McIntosh, T. J., Lasic, D. D. (1992). Repulsive interactions and mechanical stability of polymer-grafted lipid membranes. Biochim Biophys Acta 1108:40–48.
   PubMed Web of Science ®Google Scholar
• Pante, N., Kann, M. (2002). Nuclear pore complex is able to transport macromolecules with diameters of about 39 nm. Mol Biol Cell 13:425–434.
   PubMed Web of Science ®Google Scholar
• Pollard, H., Toumaniantz, G., Amos, J. L., Avet-Loiseau, H., Guihard, G., Behr, J. P., et al. (2001). Ca2+-sensitive cytosolic nucleases prevent efficient delivery to the nucleus of injected plasmids. J Gene Med 3:153–164.
   PubMed Web of Science ®Google Scholar
• Ross, G. F., Bruno, M. D., Uyeda, M., Suzuki, K., Nagao, K., Whitsett, J. A., et al. (1998). Enhanced reporter gene expression in cells transfected in the presence of DMI-2, an acid nuclease inhibitor. Gene Ther 5:1244–1250.
   PubMed Web of Science ®Google Scholar
• Rouzina, I., Bloomfield, V. A. (1998). DNA bending by small, mobile multivalent cations. Biophys J 74:3152–3164.
   PubMed Web of Science ®Google Scholar
• Shi, F., Wasungu, L., Nomden, A., Stuart, M. C., Polushkin, E., Engberts, J. B., et al. (2002). Interference of poly(ethylene glycol)-lipid analogues with cationic-lipid–mediated delivery of oligonucleotides: role of lipid exchangeability and nonlamellar transitions. Biochem J 366(Pt 1):333–341.
   PubMed Web of Science ®Google Scholar
• Talcott, B., Moore, M. S. (1999). Getting across the nuclear pore complex. Trends Cell Biol 9:312–318.
   PubMed Web of Science ®Google Scholar
• Templeton, N. S., Lasic, D. D., Frederik, P. M., Strey, H. H., Roberts, D. D., Pavlakis, G. N. (1997). Improved DNA: liposome complexes for increased systemic delivery and gene expression. Nat Biotechnol 15:647–652.
   PubMed Web of Science ®Google Scholar
• Wagner, E., Plank, C., Zatloukal, K., Cotten, M., Birnstiel, M. L. (1992a). Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci U S A 89:7934–7938.
   PubMed Web of Science ®Google Scholar
• Wagner, E., Zatloukal, K., Cotten, M., Kirlappos, H., Mechtler, K., Curiel, D. T., et al. (1992b). Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. Proc Natl Acad Sci U S A 89:6099–6103.
   PubMed Web of Science ®Google Scholar
• Walker, G. F., Fella, C., Pelisek, J., Fahrmeir, J., Boeckle, S., Ogris, M., et al. (2005). Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo. Mol Ther 11:418–425.
   PubMed Web of Science ®Google Scholar
• Wattiaux, R., Laurent, N., Wattiaux-De Coninck, S., Jadot, M. (2000). Endosomes, lysosomes: their implication in gene transfer. Adv Drug Deliv Rev 41:201–208.
   PubMed Web of Science ®Google Scholar
• Xu, Y., Szoka, F. C., Jr. (1996). Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 35:5616–5623.
   PubMed Web of Science ®Google Scholar
• Zabner, J., Fasbender, A. J., Moninger, T., Poellinger, K. A., Welsh, M. J. (1995). Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem 270:18997–19007.
   PubMed Web of Science ®Google Scholar
• Zelphati, O., Szoka, F. C., Jr. (1996). Mechanism of oligonucleotide release from cationic liposomes. Proc Natl Acad Sci U S A 93:11493–11498.
   PubMed Web of Science ®Google Scholar
• Zhou, X., Huang, L. (1994). DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action. Biochim Biophys Acta 1189:195–203.
   PubMed Web of Science ®Google Scholar