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The transcription factor, Lmx1b, promotes a neuronal glutamate phenotype and suppresses a GABA one in the embryonic trigeminal brainstem complex

The transcription factor, Lmx1b, promotes a neuronal glutamate phenotype and suppresses a GABA one in the embryonic trigeminal brainstem complex

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Pages 1-12 | Received 30 Nov 2011, Accepted 30 Nov 2011, Published online: 07 Mar 2012

References

  • Bae YC, Ihn HJ, Park MJ, Ottersen OP, Moritani M, Yoshida A, Shigenaga Y. Identification of signal substances in synapses made between primary afferents and their associated axon terminals in the rat trigeminal sensory nuclei. J Comp Neurol 2000; 418: 299–309
  • Batista MF, Lewis KE. Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons. Dev Biol 2008; 323: 88–97
  • Chaudhry FA, Reimer RJ, Bellocchio EE, Danbolt NC, Osen KK, Edwards RH, Storm-Mathisen J. The vesicular GABA transporter, VGAT, localizes to synaptic vesicles in sets of glycinergic as well as GABAergic neurons. J Neurosci 1998; 18: 9733–9750
  • Chen H, Lun Y, Ovchinnikov D, Kokubo H, Oberg KC, Pepicelli CV, Gan L, Lee B, Johnson RL. Limb and kidney defects in lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome. Nat Genet 1998; 19: 51–55
  • Chen ZF, Rebelo S, White F, Malmberg AB, Baba H, Lima D, Woolf CJ, Basbaum AI, Anderson DJ. The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron 2001; 31: 59–73
  • Cheng L, Arata A, Mizuguchi R, Qian Y, Karunaratne A, Gray PA, Arata S, Shirasawa S, Bouchard M, Luo P, et al. Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci 2004; 7: 510–517
  • Cheng L, Samad OA, Xu Y, Mizuguchi R, Luo P, Shirasawa S, Goulding M, Ma Q. Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes. Nat Neurosci 2005; 8: 1510–1515
  • Clements JR, Beitz AJ. An electron microscopic description of glutamate‐like immunoreactive axon terminals in the rat principal sensory and spinal trigeminal nuclei. J Comp Neurol 1991; 309: 271–280
  • da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han B-X, Wang F. Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-β signaling. Proc Natl Acad Sci USA 2011; 108: 3395–3400
  • Ding YQ, Yin J, Xu HM, Jacquin MF, Chen ZF. Formation of whisker-related principal sensory nucleus‐based lemniscal pathway requires a paired homeodomain transcription factor, Drg11. J Neurosci 2003; 23: 7246–7254
  • Ding YQ, Yin J, Kania A, Zhao ZQ, Johnson RL, Chen ZF. Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord. Development 2004; 131: 3693–3703
  • Dullin JP, Locker M, Robach M, Henningfeld KA, Parain K, Afelik S, Pieler T, Perron M. Ptf1a triggers GABAergic neuronal cell fates in the retina. BMC Dev Biol 2007; 7: 110
  • Erlander MG, Tillakaratne NJ, Feldblum S, Patel N, Tobin AJ. Two genes encode distinct glutamate decarboxylases. Neuron 1991; 7: 91–100
  • Erzurumlu RS, Chen ZF, Jacquin MF. Molecular determinants of the face map development in the trigeminal brainstem. Anat Rec 2006; 288: 121–134
  • Erzurumlu RS, Murakami Y, Rijli FM. Mapping the face in the somatosensory brainstem. Nat Rev Neurosci 2010; 11: 252–263
  • Fremeau RT, Troyer MD, Pahner I, Nygaard GO, Tran CH, Reimer RJ, Bellocchio EE, Fortin D, Storm‐Mathisen J, Edwards RH. The expression of vesicular glutamate transporters defines two classes of excitatory synapse. Neuron 2001; 31: 247–260
  • Furuta T, Timofeeva E, Nakamura K, Okamato‐Furuta K, Togo M, Kaneko T, Deschenes M. Inhibitory gating of vibrissal inputs in the brainstem. J Neurosci 2008; 28: 1789–1797
  • Glasgow SM, Henke RM, Macdonald RJ, Wright CV, Johnson JE. Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development 2005; 132: 5461–5469
  • Gross MK, Dottori M, Goulding M. Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord. Neuron 2002; 34: 535–549
  • Haring JH, Henderson TA, Jacquin MF. Principalis- or parabrachial-projecting spinal trigeminal neurons do not stain for GAD or GABA. Somatosens Mot Res 1990; 7: 391–398
  • Henderson TA, Woolsey TA, Jacquin MF. Infraorbital nerve blockade from birth does not disrupt central trigeminal pattern formation in the rat. Dev Brain Res 1992; 66: 146–152
  • Henderson TA, Jacquin MF. What makes subcortical barrels? Requisite trigeminal circuitry and developmental mechanisms. Barrel cortex: Vol. 11. Cerebral cortex, EG, Jones, IT Diamond. Plenum, New York 1995; 123–187
  • Hevner RF, Hodge RD, Daza RA, Englund C. Transcription factors in glutamatergic neurogenesis: Conserved programs in neocortex, cerebellum, and adult hippocampus. Neurosci Res 2006; 55: 223–233
  • Hoshino M, Nakamura S, Mori K, Kawauchi T, Terao M, Nishimura YV, Fukuda A, Fuse T, Matsuo N, Sone M, et al. Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron 2005; 47: 201–213
  • Jacquin MF, Arends JJA, Xiang C, Shapiro L, Ribak CE, Chen ZF. In Drg11 knockout mice, trigeminal cell death is extensive and does not account for failed brainstem patterning. J Neurosci 2008; 28: 3577–3585
  • Kala K, Haugas M, Lilleväli K, Guimera J, Wurst W, Salminen M, Partanen J. Gata2 is a tissue‐specific post‐mitotic selector gene for midbrain GABAergic neurons. Development 2009; 136: 253–262
  • Kaneko T, Itoh K, Shigemoto R, Mizuno N. Glutaminase-like immunoreactivity in the lower brainstem and cerebellum of the adult rat. Neurosci 1987; 32: 79–98
  • Kerr RC, Maxwell DJ, Todd AJ. GluR1 and GluR2/3 subunits of the AMPA-type glutamate receptor are associated with particular types of neurons in laminae I–III of the spinal dorsal horn of the rat. Eur J Neurosci 1998; 10: 324–333
  • Killackey HP, Fleming K. The role of the principal sensory nucleus in central trigeminal pattern formation. Brain Res 1985; 354: 141–145
  • Magnusson KR, Clements JR, Larson AA, Madl JE, Beitz AJ. Localization of glutamate in trigeminothalamic projection neurons: A combined retrograde transport-immunohistochemical study. Somatosens Res 1987; 4: 177–190
  • Minnery BS, Bruno RM, Simons DJ. Response transformation and receptive field synthesis in the lemniscal trigeminothalamic circuit. J Neurophysiol 2003; 90: 1556–1570
  • Mizuguchi R, Kriks S, Cordes R, Gossler A, Ma Q, Goulding M. Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons. Nat Neurosci 2006; 9: 770–778
  • Mugnaini E, Oertel WH. An atlas of the distribution of GABA‐ergic neurons and terminals in the rat CNS as revealed by GAD immuno‐histochemistry. Handbook of chemical neuroanatomy, A, Bjorklund, T Hokfelt. Elsevier, Amsterdam 1985; 436–608
  • Pillai A, Mansouri A, Behringer R, Westphal H, Goulding M. Lhx1 and Lhx5 maintain the inhibitory‐neurotransmitter status of interneurons in the dorsal spinal cord. Development 2007; 134: 357–366
  • Puelles E, Acampora D, Gogoi R, Tuorto F, Papalia A, Guillemot F, Ang SL, Simeone A. Otx2 controls identity and fate of glutamatergic progenitors of the thalamus by repressing GABAergic differentiation. J Neurosci 2006; 26: 5955–5964
  • Tsunekawa N, Yanagawa Y, Obata K. Development of GABAergic neurons from the ventricular zone in the superior colliculus of the mouse. Neurosci Res 2005; 51: 243–251
  • Woolsey TA. Peripheral alteration and somatosensory development. Development of sensory systems in mammals, JR Coleman. Wiley, New York 1990; 461–516
  • Xiang C, Zhang KH, Yin J, Arends JJA, Erzurumlu RS, Jacquin MF, Chen ZF. The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus‐based lemniscal pathway. Mol Cell Neurosci 2010; 44: 394–403
  • Xu Y, Lopes C, Qian Y, Liu Y, Cheng L, Goulding M, Turner EE, Lima D, Ma Q. Tlx1 and Tlx3 coordinate specification of dorsal horn pain‐modulatory peptidergic neurons. J Neurosci 2008; 28: 4037–4046

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