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Original Article

Intraocular T-cell Lymphoma: Clinical Presentation, Diagnosis, Treatment, and Outcome

, MD, , MD, , MD, , MD, PhD, , MD, , MD, PhD, , MD, PhD, , MD, PhD, , MD, , MD, , MD, , MD & , MD show all
Pages 644-653 | Received 09 Aug 2015, Accepted 05 Jan 2016, Published online: 22 Mar 2016

REFERENCES

  • Coupland SE, Damato B. Understanding intraocular lymphomas. Clin Experiment Ophthalmol. 2008;36:564–578.
  • Foester HC. Mycosis fungoides with intraocular involvement. Trans Am Acad Ophthalmol Otolaryngol. 1960;64:308–313.
  • Keltner JL, Fritsch E, Cykiert RC, et al. Mycosis fungoides. Intraocular and central nervous system involvement. Arch Ophthalmol. 1977;95:645–650.
  • Saga T, Ohno S, Matsuda H, et al. Ocular involvement by a peripheral T-cell lymphoma. Arch Ophthalmol. 1984;102:399–402.
  • Char DH, Ljung BM, Miller T, et al. Primary intraocular lymphoma (ocular reticulum cell sarcoma) diagnosis and management. Ophthalmology. 1988;95:625–630.
  • Goldey SH, Stern GA, Oblon DJ, et al. Immunophenotypic characterization of an unusual T-cell lymphoma presenting as anterior uveitis. A clinicopathologic case report. Arch Ophthalmol. 1989;107:1349–1353.
  • Erny BC, Egbert PR, Peat IM, et al. Intraocular involvement with subretinal pigment epithelium infiltrates by mycosis fungoides . Br J Ophthalmol. 1991;75:698–701. Erratum in Br J Ophthalmol. 1992;76:128.
  • Leitch RJ, Rennie IG, Parsons MA. Ocular involvement in mycosis fungoides. Br J Ophthalmol. 1993;77:126–127.
  • Jensen OA, Johansen S, Kiss K. Intraocular T-cell lymphoma mimicking a ring melanoma. First manifestation of systemic disease. Report of a case and survey of the literature. Graefes Arch Clin Exp Ophthalmol. 1994;232:148–152.
  • Kumar SR, Gill PS, Wagner DG, et al. Human T-cell lymphotropic virus type I-associated retinal lymphoma. A clinicopathologic report. Arch Ophthalmol. 1994;112:954–959.
  • Davis JL, Viciana AL, Ruiz P. Diagnosis of intraocular lymphoma by flow cytometry. Am J Ophthalmol. 1997;124:362–372.
  • Shibata K, Shimamoto Y, Nishimura T, et al. Ocular manifestations in adult T-cell leukemia/lymphoma. Ann Hematol. 1997;74:163–168.
  • Wylen EL, Williams RB, Nanda A. Cutaneous T-cell lymphoma with intracerebral and bilateral intraocular spread. Neurol Res. 1998;20:307–312.
  • Coupland SE, Foss HD, Assaf C, et al. T-cell and T/natural killer-cell lymphomas involving ocular and ocular adnexal tissues: a clinicopathologic, immunohistochemical, and molecular study of seven cases. Ophthalmology. 1999;106:2109–2120.
  • Goeminne JC, Brouillard A, Jaumain P, et al. Bilateral granulomatous panuveitis as initial presentation of diffuse systemic T cell lymphoma. Ophthalmologica. 1999;213:323–326.
  • White VA, Gascoyne RD, Paton KE. Use of the polymerase chain reaction to detect B- and T-cell gene rearrangements in vitreous specimens from patients with intraocular lymphoma. Arch Ophthalmol. 1999;117:761–765.
  • Yeh KH, Lien HC, Hsu SM, et al. Quiescent nasal T/NK cell lymphoma manifested as primary central nervous system lymphoma. Am J Hematol. 1999;60:161–163.
  • Lois N, Hiscott PS, Nash J, et al. Immunophenotypic shift in a case of mycosis fungoides with vitreous invasion. Arch Ophthalmol. 2000; 118:1692–1694.
  • Hunyor AP, Harper CA, O’Day J, et al. Ocular-central nervous system lymphoma mimicking posterior scleritis with exudative retinal detachment. Ophthalmology. 2000; 107:1955–1959.
  • Williams GC, Holz E, Lee AG, et al. T-cell lymphoproliferative disorder of vitreous associated with mycosis fungoides. Arch Ophthalmol. 2000;118:278–280.
  • Yahalom C, Cohen Y, Averbukh E, et al. Bilateral iridociliary T-cell lymphoma. Arch Ophthalmol. 2002;120:204–207.
  • Levy-Clarke GA, Buggage RR, Shen D, et al. Human T-cell lymphotropic virus type-1 associated t-cell leukemia/lymphoma masquerading as necrotizing retinal vasculitis. Ophthalmology. 2002; 109:1717–1722.
  • Hoffman PM, McKelvie P, Hall AJ, et al. Intraocular lymphoma: a series of 14 patients with clinicopathological features and treatment outcomes. Eye (Lond). 2003;17:513–521.
  • Lobo A, Larkin G, Clark BJ, et al. Pseudo-hypopyon as the presenting feature in B-cell and T-cell intraocular lymphoma. Clin Experiment Ophthalmol. 2003;31:155–158.
  • Coupland SE, Anastassiou G, Bornfeld N, et al. Primary intraocular lymphoma of T-cell type: report of a case and review of the literature. Graefes Arch Clin Exp Ophthalmol. 2005;243:189–197.
  • Levy-Clarke GA, Greenman D, Sieving PC, et al. Ophthalmic manifestations, cytology, immunohistochemistry, and molecular analysis of intraocular metastatic T-cell lymphoma: report of a case and review of the literature. Surv Ophthalmol. 2008;53:285–295.
  • Mudhar HS, Fernando M, Rennie IG, et al. Enteropathy-associated T-cell lymphoma, lacking MHC class II, with immune-privileged site recurrence, presenting as bilateral ocular vitreous humour involvement – a case report. Histopathology. 2012;61:1227–1230.
  • Alqahtani A, Touitou V, Cassoux N, et al. More Than a Masquerade Syndrome: Atypical Presentations of Vitreoretinal Lymphomas. Ocul Immunol Inflamm. 2014;22:189–196.
  • Cimino L, Chan CC, Shen D, et al. Ocular involvement in nasal natural killer T-cell lymphoma. Int Ophthalmol. 2009;29:275–279.
  • Reddy R, Kim SJ. Intraocular T-cell lymphoma due to mycosis fungoides and response to intravitreal methotrexate. Ocul Immunol Inflamm. 2011;19:234–236.
  • Siegel MJ, Dalton J, Friedman AH, et al. Ten-year experience with primary ocular ‘reticulum cell sarcoma’ (large cell non-Hodgkin’s lymphoma). Br J Ophthalmol. 1989;73:342–346.
  • Givner I. Malignant lymphoma with ocular involvement. A clinicopathologic report. Am J Ophthalmol. 1955;39:29–32.
  • Neault RW, Van Scoy RE, Okazaki H, et al. Uveitis associated with isolated reticulum cell sarcoma of the brain. Am J Ophthalmol. 1972;73:431–436.
  • Michelson JB, Michelson PE, Bordin GM, et al. Ocular reticulum cell sarcoma. Presentation as retinal detachment with demonstration of monoclonal immunoglobulin light chains on the vitreous cells. Arch Ophthalmol. 1981;99:1409–1411.
  • Gass JD, Sever RJ, Grizzard WS, et al. Multifocal pigment epithelial detachments by reticulum cell sarcoma: a characteristic funduscopic picture. Retina. 1984;4:135–143.
  • Corriveau C, Easterbrook M, Payne D. Lymphoma simulating uveitis (masquerade syndrome). Can J Ophthalmol. 1986;21:144–149.
  • Fredrick DR, Char DH, Ljung BM, et al. Solitary intraocular lymphoma as an initial presentation of widespread disease. Arch Ophthalmol. 1989;107:395–397.
  • Wender A, Adar A, Maor E, et al. Primary B-cell lymphoma of the eyes and brain in a 3-year-old boy. Arch Ophthalmol. 1994;112:450–451.
  • Gill MK, Jampol LM. Variations in the presentation of primary intraocular lymphoma: case reports and a review. Surv Ophthalmol. 2001;45:463–471.
  • Freeman LN, Schachat AP, Knox DL, et al. Clinical features, laboratory investigations, and survival in ocular reticulum cell sarcoma. Ophthalmology. 1987; 94:1631–1639.
  • Mochizuki M, Singh AD. Epidemiology and clinical features of intraocular lymphoma. Ocul Immunol Inflamm. 2009;17:69–72.
  • Fardeau C, Lee CP, Merle-Béral H, et al. Retinal fluorescein, indocyanine green angiography, and optic coherence tomography in non-Hodgkin primary intraocular lymphoma. Am J Ophthalmol. 2009;147:886–894.
  • Coupland SE, Chan CC, Smith J. Pathophysiology of retinal lymphoma. Ocul Immunol Inflamm. 2009;17:227–237.
  • Whitcup SM, de Smet MD, Rubin BI, et al. Intraocular lymphoma. Clinical and histopathologic diagnosis. Ophthalmology. 1993;100:1399–1406.
  • Ozcan AA, Paydas S, Soylu M, et al. Bilateral choroidal infiltration from indolent non-Hodgkin’s lymphoma: a rapid course with poor prognosis. Leuk Lymphoma. 2005;46:615–617.
  • Velez G, de Smet MD, Whitcup SM, et al. Iris involvement in primary intraocular lymphoma: report of two cases and review of the literature. Surv Ophthalmol. 2000;44:518–526.
  • Ursea R, Heinemann MH, Silverman RH, et al. Ophthalmic, ultrasonographic findings in primary central nervous system lymphoma with ocular involvement. Retina. 1997;17:118–123.
  • Surawicz TS, McCarthy BJ, Kupelian V, et al. Descriptive epidemiology of primary brain and CNS tumors: results from the Central Brain Tumor Registry of the United States, 1990–1994. Neuro Oncol. 1999;1:14–25.
  • Grimm SA, Pulido JS, Jahnke K, et al. Primary intraocular lymphoma: an International Primary Central Nervous System Lymphoma Collaborative Group Report. Ann Oncol. 2007; 18:1851–1855.
  • Hong JT, Chae JB, Lee JY, et al. Ocular involvement in patients with primary CNS lymphoma. J Neurooncol. 2011;102:139–145.
  • DeAngelis LM, Yahalom J, Thaler HT, et al. Combined modality therapy for primary CNS lymphoma. J Clin Oncol. 1992;10:635–643.
  • Peterson K, Gordon KB, Heinemann MH, et al. The clinical spectrum of ocular lymphoma. Cancer. 1993;72:843–849.
  • Kimura K, Usui Y, Goto H; Japanese Intraocular Lymphoma Study Group. Clinical features and diagnostic significance of the intraocular fluid of 217 patients with intraocular lymphoma. Jpn J Ophthalmol. 2012;56:383–389.
  • Cao X, Shen D, Callanan DG, et al. Diagnosis of systemic metastatic retinal lymphoma. Acta Ophthalmol. 2011;89:149–154.
  • Chan CC, Wallace DJ. Intraocular lymphoma: update on diagnosis and management. Cancer Control. 2004;11:285–295.
  • Mudhar HS, Sheard R. Diagnostic cellular yield is superior with full pars plana vitrectomy compared with core vitreous biopsy. Eye (Lond). 2013;27:50–55.
  • Davis JL. Diagnosis of intraocular lymphoma. Ocul Immunol Inflamm. 2004;12:7–16.
  • Chan CC, Whitcup SM, Solomon D, et al. Interleukin-10 in the vitreous of patients with primary intraocular lymphoma. Am J Ophthalmol. 1995;120:671–673.
  • Whitcup SM, Stark-Vancs V, Wittes RE, et al. Association of interleukin 10 in the vitreous and cerebrospinal fluid and primary central nervous system lymphoma. Arch Ophthalmol. 1997;115:1157–1160.
  • Smith JR, Rosenbaum JT, Wilson DJ, et al. Role of intravitreal methotrexate in the management of primary central nervous system lymphoma with ocular involvement. Ophthalmology. 2002;109:1709–1716.