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Ocular Immunology and Inflammation Volume 3, 1995 - Issue 3
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Original Article

Multiple recurrences in melanin-protein-induced uveitis in the rat

R. M. Broekhuyse Institute of Ophthalmology, University of Nijmegen, Nijmegen, The Netherlands
,
H. J. Winkens Institute of Ophthalmology, University of Nijmegen, Nijmegen, The Netherlands
&
E. D. Kuhlmann Institute of Ophthalmology, University of Nijmegen, Nijmegen, The Netherlands
Pages 149-155 | Accepted 01 Feb 1995, Published online: 08 Jul 2009

References

  • Nussenblatt R B, Palestine A G. Uveitis. Fundamentals and Clinical Practice. Year Book Medical Publishers, Chicago 1989; 164–184
  • McMenamin P G, Broekhuyse R M, Forrester J V. Ultrastructural pathology of experimental autoimmune uveitis: a review. Micron 1993; 24: 521–546
  • Broekhuyse R M, Kuhlmann E D, Winkens H J. Experimental autoimmune anterior uveitis (EAAU): III. Induction by immunization with purified uveal and skin melanins. Exp Eye Res 1993; 575–583
  • Broekhuyse R M, Kuhlmann E D, Winkens H J, Van Vugt A HM. Experimental autoimmune anterior uveitis (EAAU), a new form of experimental uveitis: I. Induction by a detergentinsoluble, intrinsic protein fraction of the retinal pigment epithelium. Exp Eye Res 1991; 52: 465–474
  • Broekhuyse R M, Kuhlmann E D, Winkens H J. Experimental autoimmune anterior uveitis (EAAU): II. Dose-dependent induction and adoptive transfer using a melanin-bound antigen of the retinal pigment epithelium. Exp Eye Res 1992; 55: 401–411
  • Broekhuyse R M, Kuhlmann E D. Experimental autoimmune anterior uveitis. The preparation of uveitogenic ocular melanin. Invest Ophthalmol Vis Sci 1993; 34: 698–700
  • Chan C C, Hikita N, Dastgheib K, Whitcup S M, Gery I, Nussenblatt R B. Experimental melanin-protein-induced uveitis in the Lewis rat: immunopathologic processes. Ophthalmology 1994; 101: 1275–1280
  • Chan C C, Dastgheib K, Hikita N, Walton R C, Nussenblatt R B, Gery I, Broekhuyse R M. Experimental melanin-protein induced uveitis (EMIU, formerly EAAU): immunopathology, susceptibility and therapy. Advances in Ocular Immunology, R B. Nussenblatt, S M. Whitcup, R R. Caspi, I Gery. Excerpta Medica International Congress Series 1068, Elsevier, Amsterdam 1994; 91–94
  • Caspi R R, Chan C C, Wiggert B, Chader G J. The mouse as a model of experimental autoimmune uveoretinitis (EAU). Curr Eye Res 1990; 9(Suppl)169–174
  • Broekhuyse R M, Kuhlmann E D, Winkens H J. Experimental autoimmune anterior uveitis (EAAU): Induction by melanin antigen and suppression by various treatments. Pigment Cell Res 1993; 6: 1–6

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