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Art & Infertility

Involvement of GDF-9, leptin, and IGF1 receptors associated with adipose tissue transplantation on fertility restoration in obese anovulatory mice

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Pages 759-766 | Received 31 Jul 2010, Accepted 18 Oct 2010, Published online: 11 May 2011

References

  • MitchellM, ArmstrongDT, RobkerRL, NormanRJ. Adipokines: implications for female fertility and obesity. Reproduction 2005;130:583–597.
  • ZhangY, ProencaR, MaffeiM, BaroneM, LeopoldL, FriedmanJM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425–432.
  • MantzorosCS. The role of leptin and hypothalamic neuropeptides in energy homeostasis: update on leptin in obesity. Growth Horm IGF Res 2001;11(Suppl A):S85–S89.
  • CeddiaRB, KoistinenHA, ZierathJR, SweeneyG. Analysis of paradoxical observations on the association between leptin and insulin resistance. FASEB J 2002;16:1163–1176.
  • MoschosS, ChanJL, MantzorosCS. Leptin and reproduction: a review. Fertil Steril 2002;77:433–444.
  • ColemanDL. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 1978;14:141–148.
  • HummelKP, DickieMM, ColemanDL. Diabetes, a new mutation in the mouse. Science 1966;153:1127–1128.
  • LanePW, DickieMM. Fertile, obese male mice: relative sterility in obese males corrected by dietary restriction. J Hered 1954;45:56–58.
  • LakeJK, PowerC, ColeTJ. Women's reproductive health: the role of body mass index in early and adult life. Int J Obes Relat Metab Disord 1997;21:432–438.
  • PelleymounterMA, CullenMJ, BakerMB, HechtR, WintersD, BooneT, CollinsF. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 1995;269:540–543.
  • ChehabFF, LimME, LuR. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet 1996;12:318–320.
  • MounzihK, LuR, ChehabFF. Leptin treatment rescues the sterility of genetically obese ob/ob males. Endocrinology 1997;138:1190–1193.
  • GavrilovaO, Marcus-SamuelsB, GrahamD, KimJK, ShulmanGI, CastleAL, VinsonC, EckhausM, ReitmanML. Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice. J Clin Invest 2000;105:271–278.
  • ColomboC, CutsonJJ, YamauchiT, VinsonC, KadowakiT, GavrilovaO, ReitmanML. Transplantation of adipose tissue lacking leptin is unable to reverse the metabolic abnormalities associated with lipoatrophy. Diabetes 2002;51:2727–2733.
  • SennelloJA, FayadR, PiniM, GoveME, FantuzziG. Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin-deficient ob/ob mice. Cytokine 2006;36:261–266.
  • McGrathSA, EsquelaAF, LeeSJ. Oocyte-specific expression of growth/differentiation factor-9. Mol Endocrinol 1995;9:131–136.
  • EckeryDC, WhaleLJ, LawrenceSB, WyldeKA, McNattyKP, JuengelJL. Expression of mRNA encoding growth differentiation factor 9 and bone morphogenetic protein 15 during follicular formation and growth in a marsupial, the brushtail possum (Trichosurus vulpecula). Mol Cell Endocrinol 2002;192:115–126.
  • GougeonA. Regulation of ovarian follicular development in primates: facts and hypotheses. Endocr Rev 1996;17:121–155.
  • AndradePM, SilvaID, BorraRC, LimaGR, BaracatEC. Estrogen and selective estrogen receptor modulator regulation of insulin-like growth factor binding protein 5 in the rat uterus. Gynecol Endocrinol 2002;16:265–270.
  • OnagbesanOM, VleugelsB, BuysN, BruggemanV, SafiM, DecuypereE. Insulin-like growth factors in the regulation of avian ovarian functions. Domest Anim Endocrinol 1999;17:299–313.
  • BakerJ, HardyMP, ZhouJ, BondyC, LupuF, BellveAR, EfstratiadisA. Effects of an Igf1 gene null mutation on mouse reproduction. Mol Endocrinol 1996;10:903–918.
  • ElvinJA, MatzukMM. Mouse models of ovarian failure. Rev Reprod 1998;3:183–195.
  • KutohE, BossO, LevasseurF, GiacobinoJP. Quantification of the full length leptin receptor (OB-Rb) in human brown and white adipose tissue. Life Sci 1998;62:445–451.
  • KitawakiJ, KoshibaH, IshiharaH, KusukiI, TsukamotoK, HonjoH. Expression of leptin receptor in human endometrium and fluctuation during the menstrual cycle. J Clin Endocrinol Metab 2000;85:1946–1950.
  • CioffiJA, Van BlerkomJ, AntczakM, ShaferA, WittmerS, SnodgrassHR. The expression of leptin and its receptors in pre-ovulatory human follicles. Mol Hum Reprod 1997;3:467–472.
  • KlebanovS, AstleCM, DeSimoneO, AblamunitsV, HarrisonDE. Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility. J Endocrinol 2005;186:203–211.
  • GeisthovelF, RabeT. The ESHRE/ASRM consensus on polycystic ovary syndrome (PCOS) – an extended critical analysis. Reprod Biomed Online 2007;14:522–535.
  • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004;81:19–25.
  • SeufertJ. Leptin effects on pancreatic beta-cell gene expression and function. Diabetes 2004;53(Suppl 1):S152–S158.
  • BjorbaekC, KahnBB. Leptin signaling in the central nervous system and the periphery. Recent Prog Horm Res 2004;59:305–331.
  • NagataniS, GuthikondaP, ThompsonRC, TsukamuraH, MaedaKI, FosterDL. Evidence for GnRH regulation by leptin: leptin administration prevents reduced pulsatile LH secretion during fasting. Neuroendocrinology 1998;67:370–376.
  • DuggalPS, Van Der HoekKH, MilnerCR, RyanNK, ArmstrongDT, MagoffinDA, NormanRJ. The in vivo and in vitro effects of exogenous leptin on ovulation in the rat. Endocrinology 2000;141:1971–1976.
  • RasouliN, KernPA. Adipocytokines and the metabolic complications of obesity. J Clin Endocrinol Metab 2008;93:S64–S73.
  • KadowakiT, HaraK, YamauchiT, TerauchiY, TobeK, NagaiR. Molecular mechanism of insulin resistance and obesity. Exp Biol Med (Maywood) 2003;228:1111–1117.
  • JacobiSK, AjuwonKM, WeberTE, KuskeJL, DyerCJ, SpurlockME. Cloning and expression of porcine adiponectin, and its relationship to adiposity, lipogenesis and the acute phase response. J Endocrinol 2004;182:133–144.
  • ASRM. Obesity and reproduction: an educational bulletin. Fertil Steril 2008;90:S21–S29.
  • SpicerLJ, AadPY. Insulin-like growth factor (IGF) 2 stimulates steroidogenesis and mitosis of bovine granulosa cells through the IGF1 receptor: role of follicle-stimulating hormone and IGF2 receptor. Biol Reprod 2007;77:18–27.
  • LeRoithD, WernerH, Beitner-JohnsonD, RobertsCT Jr. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev 1995;16:143–163.
  • QuJ, GodinPA, NisolleM, DonnezJ. Expression of receptors for insulin-like growth factor-I and transforming growth factor-beta in human follicles. Mol Hum Reprod 2000;6:137–145.
  • DupontJ, DunnSE, BarrettJC, LeRoithD. Microarray analysis and identification of novel molecules involved in insulin-like growth factor-1 receptor signaling and gene expression. Recent Prog Horm Res 2003;58:325–342.
  • WoodsDC, JohnsonAL. Regulation of follicle-stimulating hormone-receptor messenger RNA in hen granulosa cells relative to follicle selection. Biol Reprod 2005;72:643–650.
  • WoodsDC, JohnsonAL. Phosphatase activation by epidermal growth factor family ligands regulates extracellular regulated kinase signaling in undifferentiated hen granulosa cells. Endocrinology 2006;147:4931–4940.
  • ToscaL, ChabrolleC, CrochetS, TesseraudS, DupontJ. IGF-1 receptor signaling pathways and effects of AMPK activation on IGF-1-induced progesterone secretion in hen granulosa cells. Domest Anim Endocrinol 2008;34:204–216.
  • DuclosMJ, ChevalierB, WilliamsJ. Insulin-like growth factor-1 binding in the ovary of the domestic hen. Ann N Y Acad Sci 1998;839:510–512.
  • TrayhurnP, HoggardN, MercerJG, RaynerDV. Leptin: fundamental aspects. Int J Obes Relat Metab Disord 1999;23(Suppl 1):22–28.
  • MaamraM, BidlingmaierM, Postel-VinayMC, WuZ, StrasburgerCJ, RossRJ. Generation of human soluble leptin receptor by proteolytic cleavage of membrane-anchored receptors. Endocrinology 2001;142:4389–4393.
  • SeeberRM, SmithJT, WaddellBJ. Plasma leptin-binding activity and hypothalamic leptin receptor expression during pregnancy and lactation in the rat. Biol Reprod 2002;66:1762–1767.
  • LöfflerS, AustG, KohlerU, Spanel-BorowskiK. Evidence of leptin expression in normal and polycystic human ovaries. Mol Hum Reprod 2001;7:1143–1149.
  • Martin-RomeroC, Santos-AlvarezJ, GobernaR, Sanchez-MargaletV. Human leptin enhances activation and proliferation of human circulating T lymphocytes. Cell Immunol 2000;199:15–24.
  • AgarwalSK, VogelK, WeitsmanSR, MagoffinDA. Leptin antagonizes the insulin-like growth factor-I augmentation of steroidogenesis in granulosa and theca cells of the human ovary. J Clin Endocrinol Metab 1999;84:1072–1076.
  • DongJ, AlbertiniDF, NishimoriK, KumarTR, LuN, MatzukMM. Growth differentiation factor-9 is required during early ovarian folliculogenesis. Nature 1996;383:531–535.
  • HanrahanJP, GreganSM, MulsantP, MullenM, DavisGH, PowellR, GallowaySM. Mutations in the genes for oocyte-derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare sheep (Ovis aries). Biol Reprod 2004;70:900–909.
  • McNattyKP, JuengelJL, ReaderKL, LunS, MyllymaaS, LawrenceSB, WesternA, MeerasahibMF, MottersheadDG, GroomeNP, RitvosO, LaitinenMP. Bone morphogenetic protein 15 and growth differentiation factor 9 co-operate to regulate granulosa cell function in ruminants. Reproduction 2005;129:481–487.
  • SilvaJR, van den HurkR, van TolHT, RoelenBA, FigueiredoJR. Expression of growth differentiation factor 9 (GDF9), bone morphogenetic protein 15 (BMP15), and BMP receptors in the ovaries of goats. Mol Reprod Dev 2005;70:11–19.

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