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PCO

The lack of association between idiopathic hirsutism and metabolic disturbances: Iranian PCOS Prevalence Study

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Pages 821-825 | Received 20 Jan 2013, Accepted 26 Mar 2013, Published online: 19 Jun 2013

References

  • Azziz R, Sanchez LA, Knochenhauer ES, et al. Androgen excess in women: experience with over 1000 consecutive patients. J Clin Endocrinol Metab 2004;89:453–62
  • Zargar AH, Wani AI, Masoodi SR, et al. Epidemiologic and etiologic aspects of hirsutism in Kashmiri women in the Indian subcontinent. Fertil Steril 2002;77:674–8
  • Tehrani FR, Rashidi H, Azizi F. The prevalence of idiopathic hirsutism and polycystic ovary syndrome in the Tehran Lipid and Glucose Study. Reprod Biol Endocrinol 2011;9:144
  • Azziz R, Carmina E, Sawaya ME. Idiopathic hirsutism. Endocr Rev 2000; 21:347–62
  • Barth JH, Catalan J, Cherry CA, Day A. Psychological morbidity in women referred for treatment of hirsutism. J Psychosom Res 1993;37:615–9
  • Sonino N, Fava GA, Mani E, et al. Quality of life of hirsute women. Postgrad Med J 1993;69:186–9
  • Tekin O, Avci Z, Isik B, et al. Hirsutism: common clinical problem or index of serious disease? MedGenMed 2004;6:56--60
  • Serafini P, Lobo RA. Increased 5 alpha-reductase activity in idiopathic hirsutism. Fertil Steril 1985;43:74–8
  • Thiboutot D, Harris G, Iles V, et al. Activity of the type 1 5 alpha-reductase exhibits regional differences in isolated sebaceous glands and whole skin. J Invest Dermatol 1995;105:209–14
  • Legro RS, Shahbahrami B, Lobo RA, et al. Size polymorphisms of the androgen receptor among female Hispanics and correlation with androgenic characteristics. Obstet Gynecol 1994;83:701–6
  • Villuendas G, San Millan JL, Sancho J, et al. The −597 G–>A and −174 G–>C polymorphisms in the promoter of the IL-6 gene are associated with hyperandrogenism. J Clin Endocrinol Metab 2002;87:1134–41
  • Rossi R, Tauchmanova L, Luciano A, et al. Functional hyperandrogenism detected by corticotropin and GnRH-analogue stimulation tests in women affected by apparently idiopathic hirsutism. J Endocrinol Invest 2001;24:491–8
  • Pugeat M, Forest MG, Nisula BC, et al. Evidence of excessive androgen secretion by both the ovary and the adrenal in patients with idiopathic hirsutism. Obstet Gynecol 1982;59:46–51
  • Nichols T, Nugent CA, Tyler FH. Glucocorticoid suppression of urinary testosterone excretion in patients with idiopathic hirsutism. J Clin Endocrinol Metab 1966;26:79–86
  • Ehrmann DA, Rosenfield RL, Barnes RB, et al. Detection of functional ovarian hyperandrogenism in women with androgen excess. N Engl J Med 1992;327:157–62
  • Cebeci F, Onsun N, Mert M. Insulin resistance in women with hirsutism. Arch Med Sci 2012;8:342–6
  • Abdel Fattah NS, Darwish YW. Is there a role for insulin resistance in nonobese patients with idiopathic hirsutism? Br J Dermatol 2009;160:1011–5
  • Sarac F, Saygili F, Ozgen G, et al. Assessment of insulin resistance in the idiopathic hirsutism. Gynecol Obstet Invest 2007;63:126–31
  • Paoletti AM, Cagnacci A, Orru M, et al. Treatment with flutamide improves hyperinsulinemia in women with idiopathic hirsutism. Fertil Steril 1999;72:448–53
  • Ucak S, Basat O, Satir E, et al. Evaluation of various insulin sensitivity indices in lean idiopathic hirsutism patients. Endocr J 2012;59:291–6
  • Tehrani FR, Simbar M, Tohidi M, et al. The prevalence of polycystic ovary syndrome in a community sample of Iranian population: Iranian PCOS prevalence study. Reprod Biol Endocrinol 2011;9:39
  • Azziz R, Waggoner WT, Ochoa T, et al. Idiopathic hirsutism: an uncommon cause of hirsutism in Alabama. Fertil Steril 1998;70:274–8
  • Hatch R, Rosenfield RL, Kim MH, et al. Hirsutism: implications, etiology, and management. Am J Obstet Gynecol 1981;140:815–30
  • Pache TD, Wladimiroff JW, Hop WC, et al. How to discriminate between normal and polycystic ovaries: transvaginal US study. Radiology 1992;183:421–3
  • Chiazze L, Jr Brayer FT, Macisco JJ, Jret al. The length and variability of the human menstrual cycle. JAMA 1968;203:377–80
  • Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009;120:1640–5
  • Delavari A, Forouzanfar MH, Alikhani S, et al. First nationwide study of the prevalence of the metabolic syndrome and optimal cutoff points of waist circumference in the Middle East: the national survey of risk factors for noncommunicable diseases of Iran. Diabetes Care 2009;32:1092–7
  • Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care 2004;27:1487–95
  • Zadeh-Vakili A, Tehrani FR, Hosseinpanah F. Waist circumference and insulin resistance: a community based cross sectional study on reproductive aged Iranian women. Diabetol Metab Syndr 2011;3:18
  • Escobar-Morreale HF, Serrano-Gotarredona J, García-Robles R, et al. Abnormalities in the serum insulin-like growth factor-1 axis in women with hyperandrogenism. Fertil Steril 1998;70:1090–100
  • Shoupe D, Lobo RA. The influence of androgens on insulin resistance. Fertil Steril 1984;41:385–8
  • Reaven GM. Pathophysiology of insulin resistance in human disease. Physiol Rev 1995;75:473–86
  • Unluhizarci K, Karababa Y, Bayram F, Kelestimur F. The investigation of insulin resistance in patients with idiopathic hirsutism. J Clin Endocrinol Metab 2004;89:2741–4
  • Glintborg D, Henriksen JE, Andersen M, et al. Prevalence of endocrine diseases and abnormal glucose tolerance tests in 340 Caucasian premenopausal women with hirsutism as the referral diagnosis. Fertil Steril 2004;82:1570–9
  • Bernasconi D, Del Monte P, Meozzi M, et al. The impact of obesity on hormonal parameters in hirsute and nonhirsute women. Metabolism 1996;45:72–5
  • Toscani M, Migliavacca R, Sisson de Castro JA, Spritzer PM. Estimation of truncal adiposity using waist circumference or the sum of trunk skinfolds: a pilot study for insulin resistance screening in hirsute patients with or without polycystic ovary syndrome. Metabolism 2007;56:992–7
  • Sharp PS, Kiddy DS, Reed MJ, et al. Correlation of plasma insulin and insulin-like growth factor-I with indices of androgen transport and metabolism in women with polycystic ovary syndrome. Clin Endocrinol (Oxf) 1991;35:253–7
  • Eckel RH, Alberti KG, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet 2010;375:181–3
  • Skrha J, Haas T, Sindelka G, et al. Comparison of the insulin action parameters from hyperinsulinemic clamps with homeostasis model assessment and QUICKI indexes in subjects with different endocrine disorders. J Clin Endocrinol Metab 2004;89:135–41
  • Rosner W, Auchus RJ, Azziz R, et al. Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement. J Clin Endocrinol Metab 2007;92:405–13

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