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Research Article

Family background of Diabetes Mellitus, obesity and hypertension affects the phenotype and first symptom of patients with PCOS

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Pages 1040-1044 | Received 03 Apr 2013, Accepted 24 Jul 2013, Published online: 08 Oct 2013

References

  • Franks S. Polycystic ovary syndrome. N Engl J Med 1995;333:853–61. [Review. Erratum in: N Engl J Med 1995 Nov 23; 333(21):1435]
  • Lunde O, Magnus P, Sandvik L, Høglo S. Familial clustering in the polycystic ovarian syndrome. Gynecol Obstet Invest 1989;28:23–30
  • Govind A, Obhrai MS, Clayton RN. Polycystic ovaries are inherited as an autosomal dominant trait: analysis of 29 polycystic ovary syndrome and 10 control families. J Clin Endocrinol Metab 1999;84:38–43
  • Kahsar-Miller MD, Nixon C, Boots LR, et al. Prevalence of polycystic ovary syndrome (PCOS) in first-degree relatives of patients with PCOS. Fertil Steril 2001;75:53–8
  • Legro RS, Driscoll D, Strauss JF 3rd, et al. Evidence for a genetic basis for hyperandrogenemia in polycystic ovary syndrome. Proc Natl Acad Sci USA 1998;95:14956–60
  • Carey AH, Chan KL, Short F, et al. Evidence for a single gene effect causing polycystic ovaries and male pattern baldness. Clin Endocrinol (Oxf) 1993;38:653–8
  • Franks S, Gharani N, Waterworth D, et al. The genetic basis of polycystic ovary syndrome. Hum Reprod 1997;12:2641–8
  • Sam S, Legro RS, Essah PA, et al. Evidence for metabolic and reproductive phenotypes in mothers of women with polycystic ovary syndrome. Proc Natl Acad Sci USA 2006;103:7030–5
  • Coviello AD, Sam S, Legro RS, Dunaif A. High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity. J Clin Endocrinol Metab 2009;94:4361–6
  • Sir-Petermann T, Angel B, Maliqueo M, et al. Prevalence of Type II diabetes mellitus and insulin resistance in parents of women with polycystic ovary syndrome. Diabetologia 2002;45:959–64
  • Yildiz BO, Yarali H, Oguz H, Bayraktar M. Glucose intolerance, insulin resistance, and Hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome. J Clin Endocrinol Metab 2003;88:2031–6
  • Taylor MC, Reema Kar A, Kunselman AR, et al. Evidence for increased cardiovascular events in the fathers but not mothers of women with polycystic ovary syndrome. Hum Reprod 2011;26:2226–31
  • Dunaif A. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocr Rev 1997;18:774–800
  • Marshall JC, Dunaif A. Should all women with PCOS be treated for insulin resistance? Fertil Steril 2012;97:18–22
  • Chang WY, Knochenhauer ES, Bartolucci AA, Azziz R. Phenotypic spectrum of polycystic ovary syndrome: clinical and biochemical characterization of the three major clinical subgroups. Fertil Steril 2005;83:1717–23
  • González Centeno A, Nahum Hernández P, Mendoza R, Ayala AR. Correlation between menstruation disorders and insulin resistance. Ginecol Obstet Mex 2003;71:312–7
  • Psyrogiannis AJ, Alexopoulos DK, Kyriazopoulou VE, Vagenakis AG. Insulin resistance, hyperinsulinemia, and hypertriglyceridemia in patients with coronary artery disease independent of obesity. Angiology 1998;49:607–12
  • Job FP, Wolfertz J, Meyer R, et al. Hyperinsulinism in patients with coronary artery disease. Coron Artery Dis 1994;5:487–92
  • Uurtuya S, Kotani K, Taniguchi N, et al. Comparative study of atherosclerotic parameters in Mongolian and Japanese patients with hypertension and diabetes mellitus. J Atheroscler Thromb 2010;17:181–8
  • Quadros AS, Sarmento-Leite R, Bertoluci M, et al. Angiographic coronary artery disease is associated with progressively higher levels of fasting plasma glucose. Diabetes Res Clin Pract 2007;75:207–13
  • Benítez R, Sir-Petermann T, Palomino A, et al. Prevalence of metabolic disorders among family members of patients with polycystic ovary syndrome. Rev Med Chil 2001;129:707–12
  • Leibel NI, Baumann EE, Kocherginsky M, Rosenfield RL. Relationship of adolescent polycystic ovary syndrome to parental metabolic syndrome. J Clin Endocrinol Metab 2006;91:1275–83
  • Yilmaz M, Bukan N, Ersoy R, et al. Glucose intolerance, insulin resistance and cardiovascular risk factors in first degree relatives of women with polycystic ovary syndrome. Hum Reprod 2005;20:2414–20
  • Moini A, Eslami B. Familial associations between polycystic ovarian syndrome and common diseases. J Assist Reprod Genet 2009;26:123–7
  • Sam S, Coviello AD, Sung YA, et al. Metabolic phenotype in the brothers of women with polycystic ovary syndrome. Diabetes Care 2008;31:1237–41
  • Praveen EP, Kulshreshtha B, Khurana ML, et al. Obesity and metabolic abnormalities in offspring of subjects with diabetes mellitus. Diabetes Technol Ther 2010;12:723–30
  • Chathurvedi D, Khadgawat R, Kulshrestha B, et al. Type 2 diabetes increases risk for obesity among subsequent generations. Diabetes Technol Ther 2009;11:393–8
  • Praveen EP, Sahoo J, Khurana ML, et al. Insulin sensitivity and β-cell function in normoglycemic offspring of individuals with type 2 diabetes mellitus: impact of line of inheritance. Indian J Endocrinol Metab 2012;16:105–11
  • Chhabra S, Venkatraman S. Menstrual dysfunction in rural young women and the presence of polycystic ovarian syndrome. J Obstet Gynaecol 2010;30:41–5
  • Ibáñez L, Jaramillo A, Enríquez G, et al. Polycystic ovaries after precocious pubarche: relation to prenatal growth. Hum Reprod 2007;22:395–400
  • Ibáñez L, Potau N, Francois I, de Zegher F. Precocious pubarche, hyperinsulinism, and ovarian hyperandrogenism in girls: relation to reduced fetal growth. J Clin Endocrinol Metab 1998;83:3558–62
  • Samuelsson AM, Ohrn I, Dahlgren J, et al. Prenatal exposure to interleukin-6 results in hypertension and increased hypothalamic-pituitary-adrenal axis activity in adult rats. Endocrinology 2004;145:4897–911

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