Effects of adding luteinizing hormone activity to gonadotropin releasing hormone antagonist protocols may differ according to age

References

• Speroff L, Fritz MA. Clinical Gynecologic Endocrinology and Infertility, 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2005.
   Google Scholar
• Weghofer A, Munne S, Brannath W, Chen S, Tomkin G, Cekleniak N, Garrisi M, Barad D, Cohen J, Gleicher N. The impact of LH-containing gonadotropins on diploidy rates in preimplantation embryos: long protocol stimulation. Hum Reprod 2008;23:499–503.
   PubMed Web of Science ®Google Scholar
• Kovacs P, Kovats T, Kaali SG. Results with early follicular phase recombinant luteinizing hormone supplementation during stimulation for in vitro fertilization. Fertil Steril 2009 (E-Pub).
   Web of Science ®Google Scholar
• Ku SY, Suh CS, Kim SH, Choi YM, Kim JG, Moon SY. A pilot study of the use of low dose human menopausal gonadotropin in ovulation induction. Eur J Obstet Gynecol Reprod Biol 2003;109:55–59.
   PubMed Web of Science ®Google Scholar
• Cedrin-Durnerin I, Grange-Dujardin D, Laffy A, Parneix I, Massin N, Galey J, Theron L, Wolf JP, Conord C, Clement P, Jayot S, Hugues JN. Recombinant human LH supplementation during GnRH antagonist administration in IVF/ICSI cycles: a prospective randomized study. Hum Reprod 2004;19:1979–1984.
   PubMed Web of Science ®Google Scholar
• Ludwig M. Does the addition of luteinizing hormone in ovarian stimulation protocols improve the outcome? Treat Endocrinol 2003;2:305–313.
   PubMedGoogle Scholar
• Mochtar MH, Van der V, Ziech M, van Wely M. Recombinant luteinizing hormone (rLH) for controlled ovarian hyperstimulation in assisted reproductive cycles. Cochrane Database Syst Rev 2007: CD005070.
   PubMed Web of Science ®Google Scholar
• Kolibianakis EM, Kalogeropoulou L, Griesinger G, Papanikolaou EG, Papadimas J, Bontis J, Tarlatzis BC. Among patients treated with FSH and GnRH analogues for in vitro fertilization, is the addition of recombinant LH associated with the probability of live birth? A systematic review and meta-analysis. Hum Reprod Update 2007;13:445–452.
   PubMed Web of Science ®Google Scholar
• Baruffi RL, Mauri AL, Petersen CG, Felipe V, Martins AM, Cornicelli J, Cavagna M, Oliveira JB, Franco JG, Jr. Recombinant LH supplementation to recombinant FSH during induced ovarian stimulation in the GnRH-antagonist protocol: a meta-analysis. Reprod Biomed Online 2007;14:14–25.
   PubMed Web of Science ®Google Scholar
• Martin-Johnston M, Beltsos AN, Grotjan HE, Uhler ML. Adding human menopausal gonadotrophin to antagonist protocols – is there a benefit? Reprod Biomed Online 2007;15:161–168.
   PubMed Web of Science ®Google Scholar
• Chung K, Krey L, Katz J, Noyes N. Evaluating the role of exogenous luteinizing hormone in poor responders undergoing in vitro fertilization with gonadotropin-releasing hormone antagonists. Fertil Steril 2005;84:313–318.
   PubMed Web of Science ®Google Scholar
• Weghofer A, Munne S, Brannath W, Chen S, Barad D, Cohen J, Gleicher N. The impact of LH-containing gonadotropin stimulation on euploidy rates in preimplantation embryos: antagonist cycles. Fertil Steril 2008 (E-Pub).
   Google Scholar
• Acevedo B, Sanchez M, Gomez JL, Cuadros J, Ricciarelli E, Hernandez ER. Luteinizing hormone supplementation increases pregnancy rates in gonadotropin-releasing hormone antagonist donor cycles. Fertil Steril 2004;82:343–347.
   PubMed Web of Science ®Google Scholar
• Sauer MV, Thornton MH, IInd, Schoolcraft W, Frishman GN. Comparative efficacy and safety of cetrorelix with or without mid-cycle recombinant LH and leuprolide acetate for inhibition of premature LH surges in assisted reproduction. Reprod Biomed Online 2004;9:487–493.
   PubMed Web of Science ®Google Scholar
• Griesinger G, Schultze-Mosgau A, Dafopoulos K, Schroeder A, Schroer A, von Otte S, Hornung D, Diedrich K, Felberbaum R. Recombinant luteinizing hormone supplementation to recombinant follicle-stimulating hormone induced ovarian hyperstimulation in the GnRH-antagonist multiple-dose protocol. Hum Reprod 2005;20:1200–1206.
   PubMed Web of Science ®Google Scholar
• Levi-Setti PE, Cavagna M, Bulletti C. Recombinant gonadotrophins associated with GnRH antagonist (cetrorelix) in ovarian stimulation for ICSI: comparison of r-FSH alone and in combination with r-LH. Eur J Obstet Gynecol Reprod Biol 2006;126:212–216.
   PubMed Web of Science ®Google Scholar
• Ku SY, Choi YS, Jee BC, Suh CS, Choi YM, Kim JG, Moon SY, Kim SH. A preliminary study on reduced dose (33 or 25 microg) gonadotropin-releasing hormone agonist long protocol for multifollicular ovarian stimulation in patients with high basal serum follicle-stimulating hormone levels undergoing in vitro fertilization-embryo transfer. Gynecol Endocrinol 2005;21:227–231.
   PubMed Web of Science ®Google Scholar
• Lee JR, Kim SH, Kim SM, Jee BC, Ku SY, Suh CS, Choi YM, Kim JG, Moon SY. Follicular fluid anti-mullerian hormone and inhibin b concentrations: comparison between gonadotropin-releasing hormone (GnRH) agonist and GnRH antagonist cycles. Fertil Steril 2008;89:860–867.
   PubMed Web of Science ®Google Scholar
• Moon SY, Choi YS, Ku SY, Kim SH, Choi YM, Kang IS, Kim CH. Comparison of the efficacy and safety of a new recombinant human follicle-stimulating hormone (DA-3801) with follitropin-α (Gonal-F) in women undergoing controlled ovarian hyperstimulation for assisted reproductive technology. J Obstet Gynaecol Res 2007;33:305–315.
   PubMed Web of Science ®Google Scholar
• Veeck LL. Fertilization and early embryonic development. Curr Opin Obstet Gynecol 1992;4:702–711.
   PubMed Web of Science ®Google Scholar
• Recombinant human luteinizing hormone (LH) to support recombinant human follicle-stimulating hormone (FSH)-induced follicular development in LH- and FSH-deficient anovulatory women: a dose-finding study. The European Recombinant Human LH Study Group. J Clin Endocrinol Metab 1998;83:1507–1514.
   PubMedGoogle Scholar
• Kolibianakis EM, Collins J, Tarlatzis B, Papanikolaou E, Devroey P. Are endogenous LH levels during ovarian stimulation for IVF using GnRH analogues associated with the probability of ongoing pregnancy? A systematic review. Hum Reprod Update 2006;12:3–12.
   PubMed Web of Science ®Google Scholar
• Ruvolo G, Bosco L, Pane A, Morici G, Cittadini E, Roccheri MC. Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures. Fertil Steril 2007;87:542–546.
   PubMed Web of Science ®Google Scholar