“Short” thrombelastography as a test of platelet reactivity in response to antiplatelet therapy: Validation and reproducibility

References

• Gori A, Marcucci R, Migliorini A, Valenti R, Moschi G, Paniccia R, et al. Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents. J Am Coll Cardiol 2008; 52: 734–739
   PubMed Web of Science ®Google Scholar
• Bliden K, DiChiara J, Tantry U, Bassi A, Chaganti S, Gurbel P. Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention. Is the current antiplatelet therapy adequate?. J Am Coll Cardiol 2007; 49: 657–666
   PubMed Web of Science ®Google Scholar
• Buonamici P, Marcucci R, Migliorini A, Gensini G, Santini A, Paniccia R, et al. Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis. J Am Coll Cardiol 2007; 49: 2312–2317
   PubMed Web of Science ®Google Scholar
• Lev E, Patel R, Maresh K, Guthikonda S, Granada J, DeLao T, et al. Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention. The role of dual drug resistance. J Am Coll Cardiol 2006; 47: 27–33
   PubMed Web of Science ®Google Scholar
• Hochholzer W, Trenk D, Bestehorn HP, Fischer B, Valina C, Ferenc M, et al. Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement. J Am Coll Cardiol 2006; 48: 1742–1750
   PubMed Web of Science ®Google Scholar
• Wenaweser P, Dörffler-Melly J, Imboden K, Windecker S, Togni M, Meier B, et al. Stent thrombosis is associated with an impaired response to antiplatelet therapy. J Am Coll Cardiol 2005; 45: 1748–1752
   PubMed Web of Science ®Google Scholar
• Gum PA, Kottke-Marchant K, Welsh PA, White J, Topol E. A prospective blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol 2003; 41: 961–965
   PubMed Web of Science ®Google Scholar
• Hartert H. Thrombelastography, a method for physical analysis of blood coagulation. Z Gesampte Exp Med 1951; 117: 189–203
   PubMedGoogle Scholar
• Luddington RJ. Thrombelastography/thrombelastometry. Clin Lab Haem 2005; 27: 81–90
   PubMedGoogle Scholar
• Shore-Lesserson L, Manspeizer HE, DePerio M, Francis S, Vela-Cantos F, Ergin MA. Thrombelastography-guided transfusion algorithm reduces transfusion complex cardiac surgery. Anesth Analg 1999; 88: 312–319
   PubMed Web of Science ®Google Scholar
• Kelly GA, Tuddenham EG. Haemostatic problems in liver disease. Gut 1986; 27: 339–349
   PubMed Web of Science ®Google Scholar
• Kang YG, Martin DJ, Marquez J, Bugbee AC, Iwatsuki S, Griffith BP, et al. Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation. Anesth Analg 1985; 64: 888–896
   PubMed Web of Science ®Google Scholar
• Tantry U, Bliden K, Gurbel P. Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachidonic acid stimulation. J Am Coll Cardiol 2005; 46: 1705–1709
   PubMed Web of Science ®Google Scholar
• Gurbel PA, Bliden KP, Gruger K, Cho PW, Zaman KA, Kreutz PR, et al. Platelet Reactivity in Patients and Recurrent Events Post-Stenting: Results of the PREPARE Post-Stenting Study. J Am Coll Cardiol 2005; 46: 1820–1826
   PubMed Web of Science ®Google Scholar
• Craft RM, Chavez JJ, Bresee SY, Wortham DC, Cohen E, Caroll RC. A novel modification of the Thrombelastograph assay, isolating platelet function, correlates with optical platelet aggregation. J Lab Clin Med 2004; 143: 301–309
   PubMed Web of Science ®Google Scholar
• McGrath DJ, Ceboni E, Frumento RJ, Hirsh AL, Bennett GE. Thrombelastography maximum amplitude predicts postoperative thrombotic complications including myocardial infarction. Anesth Analg 2005; 100: 1576–1583
   PubMedGoogle Scholar
• Hobson A, Petley G, Dawkins K, Curzen N. A novel 15 minute test for assessment of individual time-dependent clotting responses to aspirin and clopidogrel using modified Thrombelastography. Platelets 2007; 18: 497–505
   PubMed Web of Science ®Google Scholar
• Swallow R, Agarwala R, Dawkins K, Curzen N. Thrombelastography: a novel bedside tool to assess the effects of antiplatelet therapy?. Platelets 2006; 17: 385–392
   PubMed Web of Science ®Google Scholar
• Hobson A, Agarwala R, Swallow R, Dawkins K, Curzen N. Thrombelastography: Current clinical applications and its potential role in interventional cardiology. Platelets 2006; 17: 509–518
   PubMed Web of Science ®Google Scholar
• Hobson A, Petley G, Morton G, Dawkins K, Curzen N. Point-of-care platelet function assays demonstrate reduced responsiveness to clopidogrel, but not aspirin, in patients with drug-eluting stent thrombosis whilst on dual antiplatelet therapy. Thromb J 2008; 21: 1–6
   Google Scholar
• Hobson A, Dawkins K, Curzen N. Antiplatelet effects of licking an aspirin tablet can be detected by thrombelastography. Acute Card Care 2008; 10: 62–63
   Google Scholar
• Hobson A, Curzen N. Improving outcomes with antiplatelet therapies in percutaneous coronary intervention and stenting. Thromb Haemost 2009; 101: 23–30
   Google Scholar
• Hobson A, Qureshi Z, Banks P, Petley G, Curzen N. Gender and responses to aspirin and clopidogrel: Insights using short thrombelastography. Cardiovasc Ther 2009; 27: 246–252
   PubMed Web of Science ®Google Scholar
• Cotton JM, Worrall AM, Hobson AR, Smallwood A, Amoah V, Dunmore S, et al. Individualised assessment of response to clopidogrel in patients presenting with acute coronary syndromes: a role for short thrombelastography?. Cardiovasc Ther 2010; 28: 139–46
   PubMed Web of Science ®Google Scholar
• Bochsen L, Winberg B, Kjelgaard-Hansen M, Steinbruchel DA, Johansson PI. Evaluation of the TEG platelet mapping assay in blood donors. Thromb J 2007; 5: 3
   PubMedGoogle Scholar
• Hobson A, Quereshi Z, Banks P, Curzen NP. Effects of clopidogrel on “aspirin specific” pathways of platelet inhibition. Platelets 2009; 20: 386–390
   PubMed Web of Science ®Google Scholar
• Marcucci R, Gori AM, Paniccia R, Giusti B, Valente S, Giglioli C, et al. Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: A 12-month follow up. Circulation 2009; 119: 237–242
   PubMed Web of Science ®Google Scholar
• Price MJ, Endemann S, Gollapudi RR, Valencia R, Stinis CT, Levisay JP, et al. Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation. Eur Heart J 2008; 29: 992–1000
   PubMed Web of Science ®Google Scholar
• Cuisset T, Hamilos M, Sarma J, Sarno G, Wyffels E, Vanderheyden M, et al. Relation of low response to clopidogrel assessed with point-of-care assay to periprocedural myonecrosis in patients undergoing elective coronary stenting for stable angina pectoris. Am J Cardiol 2008; 101: 1700–1703
   PubMed Web of Science ®Google Scholar
• Blindt R, Stellbrink K, de Taeye A, Müller R, Kiefer P, Yagmur E, et al. The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis. Thromb Haemost 2007; 98: 1329–1334
   PubMed Web of Science ®Google Scholar
• Gurbel PA, Bliden KP, Samara W, Yoho JA, Hayes K, Fissha MZ, Tantry US. Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study. J Am Coll Cardiol 2005; 46: 1827–1832
   PubMed Web of Science ®Google Scholar
• Chen WH, Lee PY, Ng W, Tse HF, Lau CP. Aspirin resistance is associated with a high incidence of myonecrosis after non-urgent percutaneous intervention despite clopidogrel pre-treatment. J Am Coll Cardiol 2004; 43: 1122–1126
   PubMed Web of Science ®Google Scholar
• Barragan P, Bouvier JL, Roquebert PO, Macaluso G, Commeau P, Comet B, et al. Resistance to thienopyridines: clinical detection of coronary stent thrombosis by monitoring of Vasodilator-Stimulated Phosphoprotein Phosphorylation. Catheter Cardiovasc Interv 2003; 59: 295–302
   PubMed Web of Science ®Google Scholar
• Cattaneo M. Update on antithrombotic therapy. New P2Y12 inhibitors. Circulation 2010; 121: 171–179
   PubMed Web of Science ®Google Scholar
• Bonello L, Camoin-Jau L, Armero S, Com O, Arques S, Burignat-Bonello C, et al. Tailored clopidogrel loading dose according to platelet reactivity monitoring to prevent acute and sub-acute stent thrombosis. Am J Cardiol 2009; 103: 5–10
   PubMed Web of Science ®Google Scholar
• Englyst N, Horsfield G, Kwan J, Byrne CD. Aspirin resistance is more common in lacunar strokes than embolic strokes and is related to stroke severity. J Cereb Blood Flow Metab 2008; 28: 1196–1203
   PubMed Web of Science ®Google Scholar
• Armstrong PCJ, Dhanji A-RA, Tucker AT, Mitchell JA, Warner TD. Reduction of platelet Thromboxane A2 production ex vivo and in vivo by clopidogrel therapy. J Thromb Haemost 2010; 8: 613–615
   PubMed Web of Science ®Google Scholar