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Original Article

Superficial skin surgery using topical 4% amethocaine gel (Ametop): A comparison with infiltrated lignocaine

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Pages 183-187 | Received 18 Feb 1997, Accepted 26 Jun 1997, Published online: 12 Jul 2009

REFERENCES

  • Monash S. Topical anaesthesia of the unbroken skin. Arch Dermatol 1957; 76: 752–6
  • Juhlin L, Evers H, Broberg F A. A lignocaine-prilacaine cream for superficial skin surgery and painful lesions. Dermatol Scand 1980; 60: 544–6
  • Woolfson A D, McCafferty D F, Boston V. Clinical experiences with a novel percutaneous amethocaine preparation: prevention of pain due to venepuncture in children. Br J Clin Pharmacol 1990; 30: 273–9
  • Small J, Wallace R G, Millar R, et al. Pain-free cutting of split skin graft by application of a percutaneous local anaesthetic cream. Br J Plast Surg 1988; 41: 339–43
  • McCafferty D F, Woolfson A D, Handley J, et al. Effect of percutaneous local anaesthetic on pain reduction during pulsed dye laser treatment of port wine stains. Br J Anaesth 1997; 78(3)286–9
  • European Patent 0175609
  • Geraint M, MacLennan A. A study to compare the speed of onset, degree and duration of anaesthesia produced by Ametop gel, 4% amethocaine Belfast gel, EMLA cream and placebo gel. Amethocaine gel a new development in effective percutaneous anaesthesia, A D Woolfson, D F McCafferty. Royal Society of Medicine Press, London May, 1996; 60–5
  • McCafferty D F, Woolfson A D, Boston V. In vivo assessment of percutaneous local anaesthetic preparation. Br J Anaesth 1989; 2: 17–21
  • Covino B G. Pharmacology of local anaesthetic agents. Br J Anaesth 1986; 58: 701–16
  • Willats D G, Reynolds F. Comparison of the vasoactivity of amide and ester local anaesthetics. Br J Anaesth 1985; 575: 1006–11
  • Mazumdar B, Tomlinson A A, Faulder G C. Preliminary study to assay plasma amethocaine concentrations after topical application of a new local anaesthetic cream containing amethocaine. Br J Anaesth 1991; 7: 432–41

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