Chromosome analysis of the differential radiosensitivity of an Epstein-Barr virus (EBV)-transformed B cell line and B and T lymphocytes from the same blood donor

References

• Baeyens A, Thierens H, Vandenbulcke K, De Ridder L, Vral A. 2004. The use of EBV-transformed cell lines of breast cancer patients to measure chromosomal radiosensitivity. Mutagenesis 19:285–290.
   PubMed Web of Science ®Google Scholar
• Bauchinger M, Schmid E. 1998. LET dependence of yield ratios of radiation-induced intra- and inter-chromosomal aberrations in human lymphocytes. International Journal of Radiation Biology 74:17–25.
   PubMed Web of Science ®Google Scholar
• Committee on the Biological Effects of Ionizing Radiation (BEIR). 2006. Health risks from exposure to low levels of ionizing radiation. BEIR VII report. Washington, DC: National Research Council of the National Academies.
   Google Scholar
• Clement LT, Dagg MK, Lehmeyer JE, Kiyotaki M. 1983. Two phenotypically distinct suppressor T cell subpopulations inhibit the induction of B cell differentiation by phytohaemagglutinin. Journal of Immunology 131:1214–1217.
   PubMedGoogle Scholar
• Conrad S, Nixdorff K, Nasonova E, Ritter S. 2006. Induction of chromosomal aberrations in human primary B lymphocytes by ionizing irradiation. GSI Scientific Report 2005, RAD-BIOPHYSICS-10, p 372.
   Google Scholar
• Göggelmann W, Jacobsen C, Panzer W, Walsh L, Roos H, Schmid E. 2003. Re-evaluation of the RBE of 29 kV X-rays (mammography X-rays) relative to 220 kV X-rays using neoplastic transformation. Radiation and Environmental Biophysics 42:175–182.
   PubMedGoogle Scholar
• Högstedt B, Karlsson A, Holmen A. 1988. Frequencies of micronuclei in human peripheral blood lymphocytes stimulated in vitro by phytohemagglutinin and pokeweed mitogen. Hereditas 109:53–55.
   PubMedGoogle Scholar
• Högstedt B, Karlsson A, Bratt I, Holmen A. 1993. Micronucleus induction in human B and T lymphocytes separated by an immunomagnetic technique. Hereditas 119:99–103.
   PubMedGoogle Scholar
• Holmen A, Karlsson A, Bratt I, Högstedt B. 1994. Micronuclei and mitotic index in B-, T4- and T8-cells treated with mitomycin C and γ-irradiation. Mutation Research 309:93–99.
   PubMed Web of Science ®Google Scholar
• International Atomic Energy Agency (IAEA). 1986. Biological dosimetry: Chromosomal aberration analysis for dose assessment. Technical Reports No. 260. Vienna: IAEA.
   Google Scholar
• International Commission on Radiological Protection (ICRP). 2003. Relative biological effectiveness (RBE), quality factor (Q), and radiation weighting factor (w_R). Publication 92. New York: Elsevier Inc.
   Google Scholar
• Kanda R, Jiang T, Hayata I, Kobayashi S. 1994. Effects of colcemid concentration on chromosome aberration analysis in human lymphocytes. Journal of Radiation Research 35:41–47.
   PubMed Web of Science ®Google Scholar
• Kaplan ME, Clark C. 1974. An improved resetting assay for detection of human T lymphocytes. Journal of Immunological Methods 5:131–135.
   PubMed Web of Science ®Google Scholar
• Kellerer AM. 2003. Error bands for the linear-quadratic dose-effect relation. Radiation and Environmental Biophysics 42:77–85.
   PubMedGoogle Scholar
• Krumrey M, Ulm G, Schmid E. 2004. Dicentric chromosomes in monolayers of human lymphocytes produced by monochromatized synchrotron radiation with photon energies from 1.83 keV to 17.4 keV. Radiation and Environmental Biophysics 43:1–6.
   PubMed Web of Science ®Google Scholar
• Neitzel H. 1986. A routine method for the establishment of permanent growing lymphoblastoid cell lines. Human Genetics 73:320–326.
   PubMed Web of Science ®Google Scholar
• Nolte R, Mühlbradt KH, Moulders JP, Stephan G, Haney M, Schmid E. 2005. RBE of quasi-monoenergetic 60 MeV neutron radiation for induction of dicentric chromosomes in human lymphocytes. Radiation and Environmental Biophysics 44:201–209.
   PubMedGoogle Scholar
• O'Donovan MR, Freemantle MR, Hull G, Bell DA, Arlett CF, Cole J. 1995a. Extended-term cultures of human T lymphocytes: A practical alternative to primary human lymphocytes for use in genotoxicity testing. Mutagenesis 10:189–201.
   PubMed Web of Science ®Google Scholar
• O'Donovan MR, Johns S, Wilcox P. 1995b. The effect of PHA stimulation on lymphocyte sub-populations in whole blood cultures. Mutagenesis 10:371–374.
   PubMed Web of Science ®Google Scholar
• Schmid E, Braselmann H, Nahrstedt U. 1995. Comparison of gamma-ray induced dicentric yields in human lymphocytes measured by conventional analysis and FISH. Mutation Research 348:125–130.
   PubMedGoogle Scholar
• Schmid E, Hieber L, Heinzmann U, Roos H, Kellerer AM. 1996. Analysis of chromosome aberrations in human peripheral lymphocytes induced by vitro α-particle irradiation. Radiation and Environmental Biophysics 35:179–184.
   PubMed Web of Science ®Google Scholar
• Schmid E, Krumrey M, Ulm G, Roos H, Regulla D. 2003. The maximum low-dose RBE of 17.4 and 40 keV monochromatic X-rays for the induction of dicentric chromosomes in human peripheral lymphocytes. Radiation Research 160:499–504.
   PubMed Web of Science ®Google Scholar
• Schmid E, Regulla D, Kramer HM, Harder D. 2002. The effect of 29 kV X rays on the dose-response of chromosome aberrations in human lymphocytes. Radiation Research 158:771–777.
   PubMed Web of Science ®Google Scholar
• Schmid E, Selbach HJ, Voth M, Pinkert J, Gildehaus FJ, Klett R, Haney M. 2006. The effect of the β-emitting yttrium-90 citrate on the dose-response of dicentric chromosomes in human lymphocytes: A basis for biological dosimetry after radiosynoviorthesis. Radiation and Environmental Biophysics 45:93–98.
   PubMedGoogle Scholar
• Schwartz JL, Gaulden ME. 1980. The relative contributions of B and T lymphocytes in the human peripheral blood mutagen test system as determined by cell survival, mitogenic stimulation, and induction of chromosome aberrations by radiation. Environmental Mutagenesis 2:473–485.
   PubMedGoogle Scholar
• Vral A, Louagie H, Thierens H, Philippe J, Cornelissen M, De Ridder L. 1998. Micronucleus frequencies in cytokinesis-blocked human B lymphocytes after low dose γ-irradiation. International Journal of Radiation Biology 73:549–555.
   PubMed Web of Science ®Google Scholar
• Vral A, Thierens H, Bryant P, De Ridder L. 2001. A higher micronucleus yield in B- versus T-cells after low-dose γ-irradiation is not linked with defective Ku86 protein. International Journal of Radiation Biology 77:329–339.
   PubMed Web of Science ®Google Scholar
• Wagner R, Schmid E, Bauchinger M. 1983. Application of conventional and FPG-staining for the analysis of chromosome aberrations induced by low levels of dose in human lymphocytes. Mutation Research 109:65–71.
   PubMedGoogle Scholar
• Weng H, Morimoto K. 2009. Differential responses to mutagens among human lymphocyte subpopulations. Mutation Research 672:1–9.
   PubMedGoogle Scholar
• Winchester RJ, Ross G. 1976. Methods for enumerating lymphocyte populations. In: Rose NR, Friedman H, editors. Manual of clinical immunology. American Society for Microbiology. pp 64–76.
   Google Scholar