Whole mouse blood microRNA as biomarkers for exposure to 𝛄-rays and ⁵⁶Fe ions

References

• Amundson SA. 2008. Functional genomics in radiation biology: A gateway to cellular systems-level studies. Radiation and Environmental Biophysics 47:25–31.
   PubMed Web of Science ®Google Scholar
• Bartel DP. 2009. MicroRNAs: Target recognition and regulatory functions. Cell 136:215–233.
   PubMed Web of Science ®Google Scholar
• Benjamini Y, Hochberg Y. 1995. Controlling the false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society B 57:289–300.
   Web of Science ®Google Scholar
• Brengues M, Paap B, Bittner M, Amundson S, Seligmann B, Korn R, Lenigk R, Zenhausern F. 2010. Biodosimetry on small blood volume using gene expression assay. Health Physics 98:179–185.
   PubMed Web of Science ®Google Scholar
• Carthew RW, Sontheimer EJ. 2009. Origins and mechanisms of miRNAs and siRNAs. Cell 136:642–655.
   PubMed Web of Science ®Google Scholar
• Cha HJ, Seong KM, Bae S, Jung JH, Kim CS, Yang KH, Jin YW, An S. 2009a. Identification of specific microRNAs responding to low and high dose gamma-irradiation in the human lymphoblast line IM9. Oncology Reports 22:863–868.
   PubMed Web of Science ®Google Scholar
• Cha HJ, Shin S, Yoo H, Lee EM, Bae S, Yang KH, Lee SJ, ParkIC, Jin YW, An S. 2009b. Identification of ionizing radiation-responsive microRNAs in the IM9 human B lymphoblastic cell line. International Journal of Oncology 34:1661–1668.
   PubMed Web of Science ®Google Scholar
• Chaudhry MA. 2009. Real-time PCR analysis of micro-RNA expression in ionizing radiation-treated cells. Cancer Biotherapy and Radiopharmaceuticals 24:49–56.
   PubMed Web of Science ®Google Scholar
• Croce CM. 2009. Causes and consequences of microRNA dysregulation in cancer. Nature Reviews Genetics 10:704–714.
   PubMed Web of Science ®Google Scholar
• Dainiak N. 2002. Hematologic consequences of exposure to ionizing radiation. Experimental Hematology 30:513–528.
   PubMed Web of Science ®Google Scholar
• Ding LH, Shingyoji M, Chen F, Chatterjee A, Kasai KE, Chen DJ. 2005. Gene expression changes in normal human skin fibroblasts induced by HZE-particle radiation. Radiation Research 164:523–526.
   PubMed Web of Science ®Google Scholar
• Dressman HK, Muramoto GG, Chao NJ, Meadows S, Marshall D, Ginsburg GS, Nevins JR, Chute JP. 2007. Gene expression signatures that predict radiation exposure in mice and humans. PLoS Medicine 4:e106.
   PubMed Web of Science ®Google Scholar
• Durante M, Snigiryova G, Akaeva E, Bogomazova A, Druzhinin S, Fedorenko B, Greco O, Novitskaya N, Rubanovich A, Shevchenko V, et al. 2003. Chromosome aberration dosimetry in cosmonauts after single or multiple space flights. Cytogenetic and Genome Research 103:40–46.
   PubMed Web of Science ®Google Scholar
• Fachin AL, Mello SS, Sandrin-Garcia P, Junta CM, Donadi EA, Passos GA, Sakamoto-Hojo ET. 2007. Gene expression profiles in human lymphocytes irradiated in vitro with low doses of gamma rays. Radiation Research 168:650–665.
   PubMed Web of Science ®Google Scholar
• Fineberg SK, Kosik KS, Davidson BL. 2009. MicroRNAs potentiate neural development. Neuron 64:303–309.
   PubMed Web of Science ®Google Scholar
• Friedman RC, Farh KK, Burge CB, Bartel DP. 2009. Most mammalian mRNAs are conserved targets of microRNAs. Genome Research 19:92–105.
   PubMed Web of Science ®Google Scholar
• George K, Chappell LJ, Cucinotta FA. 2010. Persistence of space radiation induced cytogenetic damage in the blood lymphocytes of astronauts. Mutation Research 701:75–79.
   PubMed Web of Science ®Google Scholar
• Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP. 2007. MicroRNA targeting specificity in mammals: Determinants beyond seed pairing. Molecular Cell 27:91–105.
   PubMed Web of Science ®Google Scholar
• Hunter MP, Ismail N, Zhang X, Aguda BD, Lee EJ, Yu L, Xiao T, Schafer J, Lee ML, Schmittgen TD, et al. 2008. Detection of microRNA expression in human peripheral blood microvesicles. PLoS One 3:e3694.
   PubMed Web of Science ®Google Scholar
• Ishii H, Saito T. 2006. Radiation-induced response of micro RNA expression in murine embryonic stem cells. Medicinal Chemistry 2:555–563.
   PubMedGoogle Scholar
• Josson S, Sung SY, Lao K, Chung LW, Johnstone PA. 2008. Radiation modulation of microRNA in prostate cancer cell lines. Prostate 68:1599–1606.
   PubMedGoogle Scholar
• Kloosterman WP, Plasterk RH. 2006. The diverse functions of microRNAs in animal development and disease. Developmental Cell 11:441–450.
   PubMed Web of Science ®Google Scholar
• Lee ML, Whitmore GA. 2002. Power and sample size for DNA microarray studies. Statistics in Medicine 21:3543–3570.
   PubMed Web of Science ®Google Scholar
• Maes OC, An J, Sarojini H, Wu H, Wang E. 2008. Changes in microRNA expression patterns in human fibroblasts after low-LET radiation. Journal of Cellular Biochemistry 105:824–834.
   PubMed Web of Science ®Google Scholar
• Marsit CJ, Eddy K, Kelsey KT. 2006. MicroRNA responses to cellular stress. Cancer Research 66:10843–10848.
   PubMed Web of Science ®Google Scholar
• Matsumoto Y, Iwakawa M, Furusawa Y, Ishikawa K, Aoki M, Imadome K, Matsumoto I, Tsujii H, Ando K, Imai T. 2008. Gene expression analysis in human malignant melanoma cell lines exposed to carbon beams. International Journal of Radiation Biology 84:299–314.
   PubMed Web of Science ®Google Scholar
• Mattick JS. 2004. RNA regulation: A new genetics? Nature Reviews Genetics 5:316–323.
   PubMed Web of Science ®Google Scholar
• Meadows SK, Dressman HK, Muramoto GG, Himburg H, Salter A, Wei Z, Ginsburg GS, Chao NJ, Nevins JR, Chute JP. 2008. Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. PLoS One 3:e1912.
   PubMed Web of Science ®Google Scholar
• Meadows SK, Dressman HK, Daher P, Himburg H, Russell JL, Doan P, Chao NJ, Lucas J, Nevins JR, Chute JP. 2010. Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles. PLoS One 5:e11535.
   PubMed Web of Science ®Google Scholar
• Mehler MF, Mattick JS. 2007. Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease. Physiological Reviews 87:799–823.
   PubMed Web of Science ®Google Scholar
• Negrini M, Nicoloso MS, Calin GA. 2009. MicroRNAs and cancer – new paradigms in molecular oncology. Current Opinion in Cell Biology 21:470–479.
   PubMed Web of Science ®Google Scholar
• Olsen PH, Ambros V. 1999. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Developmental Biology 216:671–680.
   PubMed Web of Science ®Google Scholar
• Ossetrova NI, Sandgren DJ, Gallego S, Blakely WF. 2010. Combined approach of hematological biomarkers and plasma protein SAA for improvement of radiation dose assessment triage in biodosimetry applications. Health Physics 98:204–208.
   PubMed Web of Science ®Google Scholar
• Paul S, Amundson SA. 2008. Development of gene expression signatures for practical radiation biodosimetry. International Journal of Radiation Oncology Biology Physics 71:1236–1244.
   PubMed Web of Science ®Google Scholar
• Peng Y, Brown N, Finnon R, Warner CL, Liu X, Genik PC, Callan MA, Ray FA, Borak TB, Badie C et al. 2009. Radiation leukemogenesis in mice: loss of PU.1 on chromosome 2 in CBA and C57BL/6 mice after irradiation with 1 GeV/nucleon 56Fe ions, X rays or gamma rays. Part I. Experimental observations. Radiation Research 171:474–483.
   PubMed Web of Science ®Google Scholar
• Pradervand S, Weber J, Lemoine F, Consales F, Paillusson A, Dupasquier M, Thomas J, Richter H, Kaessmann H, Beaudoing E, et al. 2010. Concordance among digital gene expression, microarrays, and qPCR when measuring differential expression of microRNAs. Biotechniques 48:219–222.
   Google Scholar
• QiuW, LeeMLT, WhitmoreGA. 2010. Sample size and power calculation in microarray studies using the sizepower package.
   Google Scholar
• RodriguesAS, OliveiraNG, GilOM, LeonardA, RueffJ. 2005. Use of cytogenetic indicators in radiobiology. Radiation Protection Dosimetry115:455–460.
   PubMed Web of Science ®Google Scholar
• RoyL, GruelG, VaurijouxA. 2009. Cell response to ionising radiation analysed by gene expression patterns. Annali dell Istituto Superiore di Sanita45:272–277.
   PubMed Web of Science ®Google Scholar
• ShinS, ChaHJ, LeeEM, LeeSJ, SeoSK, JinHO, ParkIC, JinYW, AnS. 2009. Alteration of miRNA profiles by ionizing radiation in A549 human non-small cell lung cancer cells. International Journal of Oncology35:81–86.
   PubMed Web of Science ®Google Scholar
• ShkumatavaA, StarkA, SiveH, BartelDP. 2009. Coherent but overlapping expression of microRNAs and their targets during vertebrate development. Genes & Development23:466–481.
   PubMed Web of Science ®Google Scholar
• SimonR, LamA, LiMC, NganM, MenenzesS, ZhaoY. 2007. Analysis of gene expression data using BRB-Array Tools. Cancer Informatics3:11–17.
   PubMedGoogle Scholar
• SimoneNL, SouleBP, LyD, SalehAD, SavageJE, DegraffW, CookJ, HarrisCC, GiusD, MitchellJB. 2009. Ionizing radiation-induced oxidative stress alters miRNA expression. PLoS One4:e6377.
   PubMed Web of Science ®Google Scholar
• SmallEM, FrostRJ, OlsonEN. 2010. MicroRNAs add a new dimension to cardiovascular disease. Circulation121:1022–1032.
   PubMed Web of Science ®Google Scholar
• SmythGK. 2004. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Statistical Applications in Genetics and Molecular Biology3:Article3.
   PubMedGoogle Scholar
• ThomasPD, CampbellMJ, KejariwalA, MiH, KarlakB, DavermanR, DiemerK, MuruganujanA, NarechaniaA. 2003. PANTHER: A library of protein families and subfamilies indexed by function. Genome Research13:2129–2141.
   PubMed Web of Science ®Google Scholar
• UmbachJL, CullenBR. 2009. The role of RNAi and microRNAs in animal virus replication and antiviral immunity. Genes & Development23:1151–1164.
   PubMed Web of Science ®Google Scholar
• YaukCL, Rowan-CarrollA, SteadJD, WilliamsA. 2010. Cross-platform analysis of global microRNA expression technologies. BMC Genomics11:330.
   PubMed Web of Science ®Google Scholar
• ZhangR, BurnsFJ, ChenH, ChenS, WuF. 2006. Alterations in gene expression in rat skin exposed to 56Fe ions and dietary vitamin A acetate. Radiation Research165:570–581.
   PubMed Web of Science ®Google Scholar