181
Views
11
CrossRef citations to date
0
Altmetric
Research Article

The involvement of serum serotonin levels producing radiation-induced bystander effects for an in vivo assay with fractionated high dose-rate (HDR) brachytherapy

, , , , , & show all
Pages 791-797 | Received 07 Jun 2012, Accepted 20 Jul 2012, Published online: 01 Aug 2012

References

  • Azzam EI, de Toledo SM, Little John B. 2003. Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect. Oncogene 22:7050–7057.
  • Bearcroft CP, Perrett D, Farthing MJG. 1998.Postprandial plasma 5-hydroxytryptamine in diarrhoea predominant irritable bowel syndrome: A pilot study.Gut42:42–46.
  • Blyth BJ, Sykes PJ. 2011. Radiation-induced bystander effects: what are they, and how relevant are they to human radiation exposures? Radiation Research 176:139–157.
  • Bodó K, Benkö G. 1987. Alterations in monoamine oxidase activity of the mouse brain and liver after mixed neutron-gamma irradiation. Acta Physiologica Hungarica 69:181–188.
  • Crompton NE, . 1997. Theory and practice of predictive assays in radiation therapy. Strahlentherapie Und Onkologie: Organ Der Deutschen Röntgengesellschaft.[et al] 173:58–67.
  • Devlin PM, editor. 2006. Brachytherapy: Applications and Techniques. 1st ed. Philadelphia, PA: Lippincott Williams, Wilkins.
  • Feldman JM. 1986. Urinary serotonin in the diagnosis of carcinoid tumors. Clinical Chemistry 32:840–844.
  • Gustafsson BI, . 2005. Long-term serotonin administration induces heart valve disease in rats. Circulation 111:1517–1522.
  • Hansen MB, Skadhauge E. 1997. Signal transduction pathways for serotonin as an intestinal secretagogue. Comparative Biochemistry and Physiology Part A: Physiology 118:283–290.
  • Hei TK, . 2008. Mechanism of radiation-induced bystander effects: A unifying model. The Journal of Pharmacy and Pharmacology 60:943–950.
  • Holland NT, . 2003. Biological sample collection and processing for molecular epidemiological studies. Mutation Research/Reviews in Mutation Research 543:217–234.
  • Kadhim MA, . 2010. Genomic instability after targeted irradiation of human lymphocytes: Evidence for inter-individual differences under bystander conditions. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 688:91–94.
  • Keszthelyi D, Troost FJ, Masclee AAM. 2009. Understanding the role of tryptophan and serotonin metabolism in gastrointestinal function. Neurogastroenterology and Motility: The Official Journal of the European Gastrointestinal Motility Society 21:1239–1249.
  • Masand PS, Gupta S. 1999. Selective serotonin-reuptake inhibitors: an update. Harvard Review of Psychiatry 7:69–84.
  • Morgan WF. 2003. Non-targeted and delayed effects of exposure to ionizing radiation: I. radiation-induced genomic instability and bystander effects in vitro. Radiation Research 159:567–580.
  • Mothersill C, Seymour C. 2001. Radiation-induced bystander effects: Past history and future directions. Radiation Research 155:759–767.
  • Mothersill C, Seymour CB. 1998. Cell-cell contact during gamma irradiation is not required to induce a bystander effect in normal human keratinocytes: Evidence for release during irradiation of a signal controlling survival into the medium. Radiation Research 149:256–262.
  • Mothersill C, . 2006. Communication of radiation-induced stress or bystander signals between fish in vivo. Environmental Science & Technology 40:6859–6864.
  • MotherSill C, Seymour C. 2012. Changing paradigms in radiobiology . Mutation Research/Reviews in Mutation Research 750:85–95.
  • Mothersill C, Moriarty M, Seymour CB. 2004. Radiotherapy and the potential exploitation of bystander effects. International Journal of Radiation Oncology Biology Physics 58:575–579.
  • Mothersill C, . 2001. Individual variation in the production of a ‘bystander Signal’ Following irradiation of primary cultures of normal human urothelium. Carcinogenesis 22:1465–1471.
  • Mothersill C, . 2010. Serum serotonin levels determine the magnitude and type of bystander effects in medium transfer experiments. Radiation Research 174:119–123.
  • Mothersill C, Seymour C. 2003. Radiation-induced bystander effects, carcinogenesis and models. Oncogene 22:7028–7033.
  • Munro AJ. 2009. Bystander effects and their implications for clinical radiotherapy. Journal of Radiological Protection: Official Journal of the Society for Radiological Protection 29:A133–142.
  • Nagasawa H, Little JB. 1992. Induction of sister chromatid exchanges by extremely low doses of alpha-particles. Cancer Research 52: 6394–6396.
  • Pirisi L, . 1988. Continuous cell lines with altered growth and differentiation properties originate after transfection of human keratinocytes with human papillomavirus type 16 DNA. Carcinogenesis 9:1573–1579.
  • Poon RCC, . 2007. Bystander effects of ionizing radiation can be modulated by signaling amines. Environmental Research 105:200–211.
  • Prise KM, . 1998. Studies of bystander effects in human fibroblasts using a charged particle microbeam. International Journal of Radiation Biology 74:793–798.
  • Saroya R, . 2009. Injection of resperpine into zebrafish, prevents fish to fish communication of radiation-induced bystander signals: Confirmation in vivo of a role for serotonin in the mechanism. Dose-Response 8:317–330.
  • Schnarr K, . 2007. Individual radiosensitivity and its relevance to health physics. Dose-Response 5:333–348.
  • Seymour CB, Mothersill C. 1997. Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment. Radiation Oncology Investigations 5:106–110.
  • Seymour C, Mothersill C. 2006. Development of an in vivo assay for detection of non-targeted radiation effects. Dose-Response: A Publication of International Hormesis Society 4:277–282.
  • Sur RK, . 1998. Fractionated high dose rate intraluminal brachytherapy in palliation of advanced esophageal cancer. International Journal of Radiation Oncology, Biology, Physics 40:447–453.
  • Widel M, . 2003. Radiation-induced micronucleus frequency in peripheral blood lymphocytes is correlated with normal tissue damage in patients with cervical carcinoma undergoing radiotherapy. Radiation Research 159:713–721.
  • Zhou H, . 2009. Consequences of cytoplasmic irradiation: studies from microbeam. Journal of radiation research 50(Suppl A): A59–65.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.