Advanced search
Publication Cover
International Journal of Radiation Biology Volume 90, 2014 - Issue 4
Submit an article Journal homepage
141
Views
16
CrossRef citations to date
0
Altmetric
ENHANCEMENT OF RADIATION EFFECTIVENESS

Enhancement of radiation effectiveness by hyperthermia and incorporation of halogenated pyrimidines at low radiation doses as compared with high doses: Implications for mechanisms

Nicolaas A. P. FrankenLaboratory for Experimental Oncology and Radiation Biology, Center for Molecular Medicine, Department of Radiation Oncology, Academic Medical Center, University of Amsterdam, The NetherlandsCorrespondence[email protected]
&
Gerrit W. BarendsenLaboratory for Experimental Oncology and Radiation Biology, Center for Molecular Medicine, Department of Radiation Oncology, Academic Medical Center, University of Amsterdam, The Netherlands
Pages 313-317 | Received 09 Sep 2013, Accepted 15 Jan 2014, Published online: 19 Mar 2014

References

  • Aten JA, Stap J, Krawczyk PM Aten JA, Stap J, Krawczyk PM, van Oven CH, Hoebe RA, Essers J, Kanaar R. 2004. Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains Science 303:92–95.
  • Barendsen GW. 1982. Dose fractionation, dose rate and iso-effect relationships for normal tissue responses. Review. Int J Radiat Oncol Biol Phys 11:1981–1997.
  • Barendsen GW. 1993. Sublethal damage and DNA double strand breaks have similar RBE-LET relationships: Evidence and implications. Int J Radiat Biol 63:325–330.
  • Barendsen GW. 1994a. RBE-LET relationships for different types of lethal radiation damage in mammalian cells: Comparison with DNA DSB and an interpretation of differences in radiosensitivity (review). Int J Radiat Biol 66:433–436.
  • Barendsen GW. 1994b. The relationships between RBE and LET for different types of lethal damage in mammalian cells: Biophysical and molecular mechanisms. Radiat Res 139:257–270.
  • Bergs JW, Krawczyk PM, Borovski T Bergs JW, Krawczyk PM, Borovski T, ten Cate R, Rodermond HM, Stap J, Medema JP, Haveman J, Essers J, van Bree C, Stalpers LJ, Kanaar R, Aten JA, Franken NAP. 2013. Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining. DNA Repair (Amst) 12:38–45.
  • Franken NAP, van Bree C, Kipp JB, Barendsen GW. 1997a. Modification of potentially lethal damage in irradiated Chinese hamster V79 cells after incorporation of halogenated pyrimidines. Int J Radiat Biol 72:101–109.
  • Franken NAP, van Bree C, Streefkerk JO, Kuper IMJA, Rodermond, HM, Kipp JBA, Haveman J, Barendsen GW. 1997b. Radiosensitization by iodo-deoxyuridine in cultured SW-1573 human lung tumor cells: Effects on alpha and beta of the linear-quadratic model. Oncol Rep 4:1073–1076.
  • Franken NAP, van Bree C, Veltmaat MA, Rodermond HM, Haveman J, Barendsen GW. 2001. Radiosensitization by bromodeoxyuridine and hyperthermia: Analysis of linear and quadratic parameters of radiation survival curves of two human tumor cell lines. J Radiat Res 42:179–190.
  • Franken NAP, Rodermond HM, Stap J, Haveman J, van Bree C. 2006. Clonogenic assay of cells in vitro. Nature Protoc 1: 2315–2319.
  • Franken NAP, ten Cate R, Krawczyk PM, Stap J, Haveman J, Aten J, Barendsen GW. 2011. Comparison of RBE values of high-LET α-particles for the induction of DNA-DSBs, chromosome aberrations and cell reproductive death. Radiat Oncol 6:64.
  • Franken NAP, Oei AL, Kok HP, Franken NA, Oei AL, Kok HP, Rodermond HM, Sminia P, Crezee J, Stalpers LJ, Barendsen GW. 2013. Cell survival and radiosensitisation: Modulation of the linear and quadratic parameters of the LQ model (review). Int J Oncol 42:1501–1515.
  • Fujii Y, Genet MD, Roybal EJ, Fujii Y, Genet MD, Roybal EJ, Kubota N, Okayasu R, Miyagawa K, Fujimori A, Kato TA. 2013. Comparison of the bromodeoxyuridine-mediated sensitization effects between low-LET and high-LET ionizing radiation on DNA double-strand breaks. Oncol Rep 29:2133–2139.
  • Krawczyk PM, Borovski T, Stap J, Krawczyk PM, Borovski T, Stap J, Cijsouw T, ten Cate R, Medema JP, Kanaar R, Franken NAP, Aten JA. 2012. Chromatin mobility is increased at sites of DNA double-strand breaks. J Cell Sci 125:2127–2133.
  • Van Bree C, Franken NAP, Bakker PJ, Klomp-Tukker LJ, Barendsen GW, Kipp JB. 1997. Hyperthermia and incorporation of halogenated pyrimidines: Radiosensitization in cultured rodent and human tumor cells. Int J Radiat Oncol, Biol Physics 39:489–496.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.