Poly(ADP-ribose) polymerase activation mediates synchrotron radiation X-ray-induced damage of rodent testes by exacerbating DNA damage and apoptotic changes

References

• Alano CC, Ying W, Swanson RA. 2004. Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition. J Biol Chem 279:18895–18902.
   PubMed Web of Science ®Google Scholar
• Barth C, Stark G, Wilhelm M. 1993. Inactivation by ionizing radiation of ion channels formed by polyene antibiotics amphotericin B and nystatin in lipid membranes: An inverse dose-rate behavior. Biophys J 64:92–97.
   PubMed Web of Science ®Google Scholar
• Beumer TL, Roepers-Gajadien HL, Gademan IS, van Buul PP, Gil-Gomez G, Rutgers DH, de Rooij DG. 1998. The role of the tumor suppressor p53 in spermatogenesis. Cell Death Differ 5:669–677.
   PubMed Web of Science ®Google Scholar
• Bonfoco E, Krainc D, Ankarcrona M, Nicotera P, Lipton SA. 1995. Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci USA 92:7162–7166.
   PubMed Web of Science ®Google Scholar
• Bouchet A, Lemasson B, Le Duc G, Maisin C, Brauer-Krisch E, Siegbahn EA, Renaud L, Khalil E, Remy C, Poillot C, Bravin A, Laissue JA, Barbier E L, Serduc R. 2010. Preferential effect of synchrotron microbeam radiation therapy on intracerebral 9L gliosarcoma vascular networks. Int J Radiat Oncol Biol Phys 78:1503–1512.
   PubMed Web of Science ®Google Scholar
• Charriaut-Marlangue C, Ben-Ari Y. 1995. A cautionary note on the use of the TUNEL stain to determine apoptosis. Neuroreport 7:61–64.
   PubMed Web of Science ®Google Scholar
• Chen H, He X, Sheng C, Ma Y, Nie H, Xia W, Ying W. 2011. Interactions between synchrotron radiation X-ray and biological tissues – theoretical and clinical significance. Int J Physiol Pathophysiol Pharmacol 3:243–248.
   PubMedGoogle Scholar
• D’Amours D, Desnoyers S, D’Silva I, Poirier GG. 1999. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem J 342:249–268.
   PubMed Web of Science ®Google Scholar
• Haines SJ. 2002. Moving targets and ghosts of the past: Outcome measurement in brain tumour therapy. J Clin Neurosci 9:109–112.
   PubMed Web of Science ®Google Scholar
• Hornsby PJ, Didenko VV. 2011. In situ ligation: A decade and a half of experience. Methods Mol Biol 682:49–63.
   PubMedGoogle Scholar
• Ishizaki K, Hayashi Y, Nakamura H, Yasui Y, Komatsu K, Tachibana A. 2004. No induction of p53 phosphorylation and few focus formation of phosphorylated H2AX suggest efficient repair of DNA damage during chronic low-dose-rate irradiation in human cells. J Radiat Res (Tokyo) 45:521–525.
   PubMed Web of Science ®Google Scholar
• Kidoguchi K, Tamaki M, Mizobe T, Koyama J, Kondoh T, Kohmura E, Sakurai T, Yokono K, Umetani K. 2006. In vivo X-ray angiography in the mouse brain using synchrotron radiation. Stroke 37: 1856–1861.
   PubMed Web of Science ®Google Scholar
• Kotenko KV, Bushmanov AY, Ozerov IV, Guryev DV, Anchishkina NA, Smetanina NM, Arkhangelskaya EY, Vorobyeva NY, Osipov AN. 2013. Changes in the number of double-strand DNA breaks in Chinese hamster V79 cells exposed to gamma-radiation with different dose rates. Int J Mol Sci 14:13719–13726.
   PubMed Web of Science ®Google Scholar
• Koufen P, Brdiczka D, Stark G. 2000. Inverse dose-rate effects at the level of proteins observed in the presence of lipids. Int J Radiat Biol 76:625–631.
   PubMed Web of Science ®Google Scholar
• Luo HR, Hattori H, Hossain MA, Hester L, Huang Y, Lee-Kwon W, Donowitz M, Nagata E, Snyder SH. 2003. Akt as a mediator of cell death. Proc Natl Acad Sci USA 100:11712–11717.
   PubMed Web of Science ®Google Scholar
• Ma Y, Chen H, He X, Nie H, Hong Y, Sheng C, Wang Q, Xia W, Ying W. 2012a. NAD+ metabolism and NAD+-dependent enzymes: Promising therapeutic targets for neurological diseases. Curr Drug Targets 13:222–229.
   PubMed Web of Science ®Google Scholar
• Ma Y, Nie H, Sheng C, Chen H, Wang B, Liu T, Shao J, He X, Zhang T, Zheng C, Xia W, Ying W. 2012b. Roles of oxidative stress in synchrotron radiation X-ray-induced testicular damage of rodents. Int J Physiol Pathophysiol Pharmacol 4:108–114.
   PubMedGoogle Scholar
• Porter AG, Janicke RU. 1999. Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6:99–104.
   PubMed Web of Science ®Google Scholar
• Przybyszewski WM, Widel M, Palyvoda O. 2002. Lipid peroxidation, DNA damage, and cellular morphology of R1 Rhabdomyosarcoma cell line irradiated in vitro by gamma-rays with different dose rates. Teratog Carcinog Mutagen 22:93–102.
   PubMedGoogle Scholar
• Serduc R, Bouchet A, Brauer-Krisch E, Laissue JA, Spiga J, Sarun S, Bravin A, Fonta C, Renaud L, Boutonnat J, Siegbahn EA, Esteve F, Le Duc G. 2009. Synchrotron microbeam radiation therapy for rat brain tumor palliation-influence of the microbeam width at constant valley dose. Phys Med Biol 54:6711–6724.
   PubMed Web of Science ®Google Scholar
• Sheng C, Chen H, Wang B, Liu T, Hong Y, Shao J, He X, Ma Y, Nie H, Liu N, Xia W, Ying, W. 2012. NAD+ administration significantly attenuates synchrotron radiation X-ray-induced DNA damage and structural alterations of rodent testes. Int J Physiol Pathophysiol Pharmacol 4:1–9.
   PubMedGoogle Scholar
• Smilowitz HM, Blattmann H, Brauer-Krisch E, Bravin A, Di Michiel M, Gebbers JO, Hanson AL, Lyubimova N, Slatkin DN, Stepanek J, Laissue JA. 2006. Synergy of gene-mediated immunoprophylaxis and microbeam radiation therapy for advanced intracerebral rat 9L gliosarcomas. J Neurooncol 78:135–143.
   PubMed Web of Science ®Google Scholar
• Stark G. 1991. The effect of ionizing radiation on lipid membranes. Biochim Biophys Acta 1071:103–122.
   PubMed Web of Science ®Google Scholar
• Suortti P, Thomlinson W. 2003. Medical applications of synchrotron radiation. Phys Med Biol 48:R1–35.
   PubMed Web of Science ®Google Scholar
• Walker PR, Carson C, Leblanc J, Sikorska M. 2002. Labeling DNA damage with terminal transferase. Applicability, specificity, and limitations. Methods Mol Biol 203:3–19.
   PubMedGoogle Scholar
• Weaver AN, Yang ES. 2013. Beyond DNA repair: Additional functions of PARP-1 in cancer. Front Oncol 3:290.
   PubMedGoogle Scholar
• Wolvekamp MC, Darby IA, Fuller PJ. 1998. Cautionary note on the use of end-labelling DNA fragments for detection of apoptosis. Pathology 30:267–271.
   PubMed Web of Science ®Google Scholar
• Veuger SJ, Hunter JE, Durkacz BW. 2009. Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance. Oncogene 28:832–842.
   PubMed Web of Science ®Google Scholar
• Virag L, Szabo C. 2002. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 54:375–429.
   PubMed Web of Science ®Google Scholar
• Wang S, Xing Z, Vosler PS, Yin H, Li W, Zhang F, Signore AP, Stetler RA, Gao Y, Chen J. 2008. Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: Role of enhanced DNA repair. Stroke 39:2587–2595.
   PubMed Web of Science ®Google Scholar
• Ying W. 2008. NAD+/NADH and NADP+/NADPH in cellular functions and cell death: Regulation and biological consequences. Antioxid Redox Signal 10:179–206.
   PubMed Web of Science ®Google Scholar
• Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. 2002. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297:259–263.
   PubMed Web of Science ®Google Scholar