Hepatocyte senescence induced by radiation and partial hepatectomy in rat liver

References

• Acosta JC, O’Loghlen A, Banito A, Guijarro MV, Augert A, Raguz S, Fumagalli M, Da Costa M, Brown C, Popov N, et al. 2008. Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell 133:1006–1018.
   PubMed Web of Science ®Google Scholar
• Albrecht JH, Poon RY, Ahonen CL, Rieland BM, Deng C, Crary GS. 1998. Involvement of p21 and p27 in the regulation of CDK activity and cell cycle progression in the regenerating liver. Oncogene 16:2141–2150.
   PubMed Web of Science ®Google Scholar
• Becker AJ, Mc CE, Till JE. 1963. Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature 197:452–454.
   PubMed Web of Science ®Google Scholar
• Christiansen H, Koenig S, Krause P, Hermann RM, Rave-Frank M, Proehl T, Becker H, Hess CF, Schmidberger H. 2006. External-beam radiotherapy as preparative regimen for hepatocyte transplantation after partial hepatectomy. Int J Radiat Oncol Biol Phys 65:509–516.
   PubMed Web of Science ®Google Scholar
• Christiansen H, Sheikh N, Saile B, Reuter F, Rave-Frank M, Hermann RM, Dudas J, Hille A, Hess CF, Ramadori G. 2007. x-Irradiation in rat liver: Consequent upregulation of hepcidin and downregulation of hemojuvelin and ferroportin-1 gene expression. Radiology 242:189–197.
   PubMed Web of Science ®Google Scholar
• Citrin DE, Shankavaram U, Horton JA, Shield W 3rd, Zhao S, Asano H, White A, Sowers A, Thetford A, Chung EJ. 2013. Role of type II pneumocyte senescence in radiation-induced lung fibrosis. J Natl Cancer Inst 105:1474–1484.
   PubMedGoogle Scholar
• Coppe JP, Desprez PY, Krtolica A, Campisi J. 2010. The senescence- associated secretory phenotype: The dark side of tumor suppression. Annu Rev Pathol 5:99–118.
   PubMed Web of Science ®Google Scholar
• Coppe JP, Patil CK, Rodier F, Sun Y, Munoz DP, Goldstein J, Nelson PS, Desprez PY, Campisi J. 2008. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol 6:2853–2868.
   PubMed Web of Science ®Google Scholar
• De Vree JM, Ottenhoff R, Bosma PJ, Smith AJ, Aten J, Oude Elferink RP. 2000. Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis. Gastroenterology 119:1720–1730.
   PubMed Web of Science ®Google Scholar
• Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O, et al. 1995. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92:9363–9367.
   PubMed Web of Science ®Google Scholar
• Guha C, Sharma A, Gupta S, Alfieri A, Gorla GR, Gagandeep S, Sokhi R, Roy-Chowdhury N, Tanaka KE, Vikram B, et al. 1999. Amelioration of radiation-induced liver damage in partially hepatectomized rats by hepatocyte transplantation. Cancer Res 59:5871–5874.
   PubMed Web of Science ®Google Scholar
• Itahana K, Campisi J, Dimri GP. 2007. Methods to detect biomarkers of cellular senescence: The senescence-associated beta-galactosidase assay. Meth Molec Biol 371:21–31.
   PubMedGoogle Scholar
• Karnezis AN, Dorokhov M, Grompe M, Zhu L. 2001. Loss of p27(Kip1) enhances the transplantation efficiency of hepatocytes transferred into diseased livers. J Clin Investigat 108:383–390.
   PubMedGoogle Scholar
• Koenig S, Krause P, Schmidt TK, Rave-Fraenk M, Rothe H, Hermann RM, Becker H, Hess CF, Christiansen H. 2008. Irradiation as preparative regimen for hepatocyte transplantation causes prolonged cell cycle block. Int J Radiat Biol 84:285–298.
   PubMed Web of Science ®Google Scholar
• Kuilman T, Peeper DS. 2009. Senescence-messaging secretome: SMS-ing cellular stress. Nature Rev Cancer 9:81–94.
   PubMed Web of Science ®Google Scholar
• Kuilman T, Michaloglou C, Vredeveld LC, Douma S, van Doorn R, Desmet CJ, Aarden LA, Mooi WJ, Peeper DS. 2008. Oncogene- induced senescence relayed by an interleukin-dependent inflammatory network. Cell 133:1019–1031.
   PubMed Web of Science ®Google Scholar
• Laberge RM, Zhou L, Sarantos MR, Rodier F, Freund A, de Keizer PL, Liu S, Demaria M, Cong YS, Kapahi P, et al. 2012. Glucocorticoids suppress selected components of the senescence-associated secretory phenotype. Aging Cell 11:569–578.
   PubMed Web of Science ®Google Scholar
• Laconi E, Sarma DS, Pani P. 1995. Transplantation of normal hepatocytes modulates the development of chronic liver lesions induced by a pyrrolizidine alkaloid, lasiocarpine. Carcinogenesis 16:139–142.
   PubMed Web of Science ®Google Scholar
• Laconi E, Oren R, Mukhopadhyay DK, Hurston E, Laconi S, Pani P, Dabeva MD, Shafritz DA. 1998. Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine. Am J Pathol 153:319–329.
   PubMed Web of Science ®Google Scholar
• Laconi S, Pillai S, Porcu PP, Shafritz DA, Pani P, Laconi E. 2001. Massive liver replacement by transplanted hepatocytes in the absence of exogenous growth stimuli in rats treated with retrorsine. Am J Pathol 158:771–777.
   PubMedGoogle Scholar
• Laconi S, Curreli F, Diana S, Pasciu D, De Filippo G, Sarma DS, Pani P, Laconi E. 1999. Liver regeneration in response to partial hepatectomy in rats treated with retrorsine: A kinetic study. J Hepatol 31:1069–1074.
   PubMed Web of Science ®Google Scholar
• Lee BY, Han JA, Im JS, Morrone A, Johung K, Goodwin EC, Kleijer WJ, DiMaio D, Hwang ES. 2006. Senescence-associated beta-galactosidase is lysosomal beta-galactosidase. Aging Cell 5: 187–195.
   PubMed Web of Science ®Google Scholar
• Leontieva OV, Gudkov AV, Blagosklonny MV. 2010. Weak p53 permits senescence during cell cycle arrest. Cell Cycle 9:4323–4327.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402–408.
   PubMed Web of Science ®Google Scholar
• Malhi H, Gorla GR, Irani AN, Annamaneni P, Gupta S. 2002. Cell transplantation after oxidative hepatic preconditioning with radiation and ischemia-reperfusion leads to extensive liver repopulation. Proc Natl Acad Sci USA 99:13114–13119.
   PubMed Web of Science ®Google Scholar
• Mignon A, Guidotti JE, Mitchell C, Fabre M, Wernet A, De La Coste A, Soubrane O, Gilgenkrantz H, Kahn A. 1998. Selective repopulation of normal mouse liver by Fas/CD95-resistant hepatocytes. Nat Med 4:1185–1188.
   PubMedGoogle Scholar
• Overturf K, Al-Dhalimy M, Tanguay R, Brantly M, Ou CN, Finegold M, Grompe M. 1996. Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I. Nat Genet 12:266–273.
   PubMed Web of Science ®Google Scholar
• Rhim JA, Sandgren EP, Degen JL, Palmiter RD, Brinster RL. 1994. Replacement of diseased mouse liver by hepatic cell transplantation. Science 263:1149–1152.
   PubMed Web of Science ®Google Scholar
• Rodier F, Campisi J. 2011. Four faces of cellular senescence. J Cell Biol 192:547–456.
   PubMed Web of Science ®Google Scholar
• Salminen A, Kauppinen A, Kaarniranta K. 2012. Emerging role of NF-kappaB signaling in the induction of senescence-associated secretory phenotype (SASP). Cell Signal 24:835–845.
   PubMed Web of Science ®Google Scholar
• Sandgren EP, Palmiter RD, Heckel JL, Daugherty CC, Brinster RL, Degen JL. 1991. Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene. Cell 66:245–256.
   PubMed Web of Science ®Google Scholar
• Seol MA, Jung U, Eom HS, Kim SH, Park HR, Jo SK. 2012. Prolonged expression of senescence markers in mice exposed to gamma- irradiation. J Vet Sci 13:331–338.
   PubMed Web of Science ®Google Scholar
• Serra MP, Marongiu F, Sini M, Laconi E. 2012. Hepatocyte senescence in vivo following preconditioning for liver repopulation. Hepatology 56:760–788.
   PubMedGoogle Scholar
• Sigal SH, Rajvanshi P, Gorla GR, Sokhi RP, Saxena R, Gebhard DR Jr, Reid LM, Gupta S. 1999. Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events. Am J Physiol 276:G1260–1272.
   PubMed Web of Science ®Google Scholar
• Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC. 1985. Measurement of protein using bicinchoninic acid. Anal Biochem 150:76–85.
   PubMed Web of Science ®Google Scholar
• Streetz KL, Luedde T, Manns MP, Trautwein C. 2000. Interleukin 6 and liver regeneration. Gut 47:309–312.
   PubMed Web of Science ®Google Scholar
• Suzuki M, Boothman DA. 2008. Stress-induced premature senescence (SIPS) – influence of SIPS on radiotherapy. J Radiat Res 49:105–112.
   PubMed Web of Science ®Google Scholar
• Wang Y, Scheiber MN, Neumann C, Calin GA, Zhou D. 2011. MicroRNA regulation of ionizing radiation-induced premature senescence. Int J Radiat Oncol Biol Phys 81:839–848.
   PubMed Web of Science ®Google Scholar
• Wang Y, Schulte BA, LaRue AC, Ogawa M, Zhou D. 2006. Total body irradiation selectively induces murine hematopoietic stem cell senescence. Blood 107:358–366.
   PubMed Web of Science ®Google Scholar
• Witek RP, Fisher SH, Petersen BE. 2005. Monocrotaline, an alternative to retrorsine-based hepatocyte transplantation in rodents. Cell Transplant 14:41–47.
   PubMedGoogle Scholar