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Point-of-use micronutrient fortification: lessons learned in implementing a preschool-based pilot trial in South Africa

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Pages 1-16 | Published online: 12 Aug 2010

References

  • Andersson M, Thankachan P, Muthayya S, Goud RB, Kurpad AV, Hurrell RF, Zimmermann MB. 2008. Dual fortification of salt with iodine and iron: a randomized, double-blind, controlled trial of micronized ferric pyrophosphate and encapsulated ferrous fumarate in southern India. Am J Clin Nutr. 88 5: 1378–1387.
  • Ayoya MA, Spiekermann-Brouwer GM, Traoré AK, Stoltzfus RJ, Habicht JP, Garza C. 2009. Multiple micronutrients including iron are not more effective than iron alone for improving hemoglobin and iron status of Malian school children. J Nutr. 139 10: 1972–1979.
  • Behrman JR, Glewwe P, Miguel Eeditors. 2007. Methodologies to Evaluate Early Childhood Development ProgramsWashington, DC: World Bank.
  • Benton D, Brett V, Brain P. 1987. Glucose improves attention and reaction to frustration in children. Biol Psychol. 24 2: 95–100.
  • Benton D, Ruffin MP, Lassel T, Nabb S, Messaoudi M, Vinoy S, Desor D, Lang V. 2003. The delivery rate of dietary carbohydrates affects cognitive performance in both rats and humans. Psychopharmacology. 166 1: 86–90.
  • Black RE, Morris SS, Bryce J. 2003. Where and why are 10 million children dying every year?. Lancet. 361 9376: 2226–2234.
  • Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, Mathers C, Rivera J, Maternal and Child Undernutrition Study Group. 2008. Maternal and child undernutrition: Global and regional exposures and health consequences. Lancet. 371 9608: 243–260.
  • Bonnet E, Touyarot K, Alfos S, Pallet V, Higueret P, Abrous DN. 2008. Retinoic acid restores adult hippocampal neurogenesis and reverses spatial memory deficit in vitamin A deprived rats. PloS One. 3 10: e3487.
  • Bourre JM. 2006. Effects of nutrients (in food) on the structure and function of the nervous system: Update on dietary requirements for brain. part 1: micronutrients. J Nutr Health Aging. 10 5: 377–385.
  • Cicchetti DV. 1994. Guidelines, criteria, and rules of thumb for evaluating normed and standardized assessment instruments in psychology. Psychol Assess. 6 4: 284–290.
  • Cohen J. 1988. Statistical Power Analysis for Behavioural Sciences. Hillsdale, NJ: Lawrence Earlbaum Associates.
  • Corniola RS, Tassabehji NM, Hare J, Sharma G, Levenson CW. 2008. Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms. Brain Res. 27 1237: 52–61.
  • De Pee S, Kraemer K, van den Briel T, Boy E, Grasset C, Moench-Pfanner R, Zlotkin S, Bloem MW, World Food Programme, Sprinkles Global Health Initiative. 2008. Quality criteria for micronutrient powder products: Report of a meeting organized by the world food programme and sprinkles global health initiative. Food Nutr Bull. 29 3: 232–241.
  • Ellis SM, Steyn HS. 2003. Practical significance (effect sizes) versus or in combination with statistical significance (p-values). Manage Dynamics. 12 4: 51–53.
  • Faber M, Kvalsvig JD, Lombard CJ, Benade AJ. 2005. Effect of a fortified maize-meal porridge on anemia, micronutrient status, and motor development of infants. Am J Clin Nutr. 82 5: 1032–1039.
  • Fletcher-Janzen E, Daniel MH. 2006. Socio-economic Status Research. AGS Publishing: Pearson Assessments. Available online at: http://www.ags.pearsonassessments.com (accessed 6 March 2008).
  • Frederickson CJ. 1989. Neurobiology of zinc and zinc-containing neurons. Int Rev Neurobiol. 31:145–238.
  • Gardner G, Gardner A, MacLellan L, Osborne S. 2003. Reconceptualising the objectives of a pilot study for clinical research. Int J Nurs Stud. 40 7: 719–724.
  • Giedd JN, Blumenthal J, Jeffries NO, Castellanos FX, Liu H, Zijdenbos A, Paus T, Evans AC, Rapoport JL. 1999. Brain development during childhood and adolescence: A longitudinal MRI study. Nat Neurosci. 2 10: 861–863.
  • Gilsenan MB, De Bruin EA, Dye L. 2009. The influence of carbohydrate on cognitive performance: A critical evaluation from the perspective of glycaemic load. Br J Nutr. 101 7: 941–949.
  • Giovannini M, Sala D, Usuelli M, Livio L, Francescato G, Braga M, Radaelli G, Riva E. 2006. Double-blind, placebo-controlled trial comparing effects of supplementation with two different combinations of micronutrients delivered as sprinkles on growth, anemia, and iron deficiency in Cambodian infants. J Pediatr Gastroenterol Nutr. 42 3: 306–312.
  • Gordon RC, Rose MC, Skeaff SA, Gray AR, Morgan KMD, Ruffman T. 2009. Iodine supplementation improves cognition in mildly iodine-deficienct children. Am J Clin Nutr. 90 5: 1264–1271.
  • Grantham-McGregor S, Cheung YB, Cueto S, Glewwe P, Richter L, Strupp B, International Child Development Steering Group. 2007. Developmental potential in the first 5 years for children in developing countries. Lancet. 369 9555: 60–70.
  • Hallberg L, Brune M, Erlandsson M, Sandberg AS, Rossanderhulten L. 1991. Calcium—effect of different amounts on nonheme-iron and heme-iron absorption in humans. Am J Clin Nutr. 53:112–119.
  • Haskell CF, Scholey AB, Jackson PA, Elliot JM, Defeyter MA, Greer J, Robertson BC, Bauchanan T, Tiplady B, Kennedy DO. 2008. Cognitive and mood effects in healthy children during 12 weeks' supplementation with multi-vitamin/minerals. Br J Nutr. 100 5: 1086–1096.
  • Hurrell RF. 2007. Iron fortification: its efficacy and safety in relation to infections. Food Nutr Bull. 28 4 Suppl: S585–S594.
  • International Society for the Advancement of Kinanthropometry. 2001. International Standards for Anthropometric Assessment. Potchefstroom, South Africa: ISAK.
  • Isaacs E, Oates J, ILSI Europe a.i.s.b.l.. 2008. Nutrition and cognition: Assessing cognitive abilities in children and young people. Eur J Nutr. 47 Suppl 3: 4–24.
  • Kalman DS, Lou L, Schwartz HI, Feldman S, Krieger DR. 2009. A pilot trial comparing the availability of vitamins C, B(6), and B(12) from a vitamin-fortified water and food source in humans. Int J Food Sci Nutr. 60 Suppl 5: S114–S124.
  • Kaufman AS, Lichtenberger EO, Fletcher-Janzen E, Kaufman NL. 2005. Essentials of KABC-II Assessment. Hoboken, NJ: John Wiley & Sons, Inc.
  • Kenward MG, Carpenter J. 2007. Multiple imputation: Current perspectives. Stat Methods Med Res. 16 3: 199–218.
  • Kong AS, Sussman AL, Negrete S, Patterson N, Mittleman R, Hough R. 2009. Implementation of a walking school bus: Lessons learned. J Sch Health. 79 7: 319–325.
  • Kordas K, Stoltzfus RJ. 2004. New evidence of iron and zinc interplay at the enterocyte and neural tissues. J Nutr. 134 6: 1295–1298.
  • Labadarios D, Swart R, Maunder E, Kruger HS, Gericke G, Kuzwayo PMN, Ntsie PR, Steyn NP, Schloss I, . 2008. Executive summary of the national food consumption survey-fortification baseline (NFCS-FB-I): South Africa, 2005. South Afr J Clin Nutr. 21 3: 245–300 (Suppl 2).
  • Lancaster GA, Dodd S, Williamson PR. 2004. Design and analysis of pilot studies: Recommendations for good practice. J Eval Clin Pract. 10 2: 307–312.
  • Lind T, Lönnerdal B, Stenlund H, Ismail D, Seswandhana R, Ekström EC, Persson LA. 2003. A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: Interactions between iron and zinc. Am J Clin Nutr. 77 4: 883–890.
  • Loechl CU, Menon P, Arimond M, Ruel MT, Pelto G, Habicht JP, Michaud L. 2009. Using programme theory to assess the feasibility of delivering micronutrient sprinkles through a food-assisted maternal and child health and nutrition programme in rural haiti. Matern Child Nutr. 5 1: 33–48.
  • Lopriore C, Guidoum Y, Briend A, Branca F. 2004. Spread fortified with vitamins and minerals induces catch-up growth and eradicates severe anemia in stunted refugee children aged 3–6 years. Am J Clin Nutr. 80 4: 973–981.
  • Lozoff B, Georgieff MK. 2006. Iron deficiency and brain development. Seminars Pediatr Neurol. 13 3: 158–165.
  • Mahoney CR, Taylor HA, Kanarek RB, Samuel P. 2005. Effect of breakfast composition on cognitive processes in elementary school children. Physiol Behav. 85 5: 635–645.
  • Manger MS, Mckenzie JE, Winichagoon P, Gray A, Chavasit V, Pongcharoen T, Gowachirapant S, Ryan B, Wasantwisut E, Gibson RS. 2008. A micronutrient-fortified seasoning powder reduces morbidity and improves short-term cognitive function, but has no effect on anthropometric measures in primary school children in northeast Thailand: A randomized controlled trial. Am J Clin Nutr. 87 6: 1715–1722.
  • Menon P, Ruel MT, Loechl CU, Arimond M, Habicht JP, Pelto G, Michaud L. 2007. Micronutrient sprinkles reduce anemia among 9- to 24-mo-old children when delivered through an integrated health and nutrition program in rural haiti. J Nutr. 137 4: 1023–1030.
  • Metallinos-Katsaras E, Valassi-Adam E, Dewey KG, Lonnerdal B, Stamoulakatou A, Pollitt E. 2004. Effect of iron supplementation on cognition in Greek preschoolers. Eur J Clin Nutr. 58 11: 1532–1542.
  • Moher D, Schulz KF, Altman DG. 2001. The CONSORT statement: Revised recommendations for improving the quality of reports of parallel-group randomised trials. Lancet. 357 9263: 1191–1194.
  • Murphy SP, Gewa C, Liang L, Grillenberger M, Bwibo NO, Neumann CG. 2003. School Snacks containing animal source foods improve dietary quality for children in rural Kenya. J Nutr. 133 11 Suppl 2: 3950S–3956S.
  • Muthayya S, Eilander A, Transler C, Thomas T, van der Knaap HC, Srinivasan K, van Klinken BJ, Osendarp SJ, Kurpad AV. 2009. Effect of fortification with multiple micronutrients and n-3 fatty acids on growth and cognitive performance in Indian schoolchildren: The CHAMPION (Children's Health and Mental Performance Influenced by Optimal Nutrition) Study. Am J Clin Nutr. 89 6: 1766–1775.
  • Robert RC, Gittelsohn J, Creed-Kanashiro HM, Penny ME, Caulfield LE, Narro MR, Black RE. 2006. Process evaluation determines the pathway of success for a health center-delivered, nutrition education intervention for infants in Trujillo, Peru. J Nutr. 136 3: 634–641.
  • Rossi PH, Lipsey MW, Freeman HE. 2004. Evaluation: A Systematic Approach. Thousand Oaks, CA: Sage.
  • Schenker Y, Wang F, Selig SJ, Ng R, Fernandez A. 2007. The impact of language barriers on documentation of informed consent at a hospital with on-site interpreter services. J Gen Intern Med. 22 Suppl 2: 294–299.
  • Sharieff W, Yin SA, Wu M, Yang Q, Schauer C, Tomlinson G, Zlotkin S. 2006. Short-term daily or weekly administration of micronutrient Sprinkles has high compliance and does not cause iron overload in Chinese schoolchildren: A cluster-randomised trial. Public Health Nutr. 9 3: 336–344.
  • Smuts CM, Dhansay MA, Faber M, Van Stuijvenberg ME, Swanevelder S, Gross R, Benadé AJ. 2005. Efficacy of multiple micronutrient supplementation for improving anemia, micronutrient status, and growth in South African infants. J Nutr. 135 3: 653S–659S.
  • Steyn NP, Marais D. 2002. Children have a right to meals of good nutritional quality at state-subsidised crèches. South Afr J Clin Nutr. 15 2: 3.
  • Stoltzfus RJ, Kvalsvig JD, Chwaya HM, Montresor A, Albonico M, Tielsch JM, Savioli L, Pollitt E. 2001. Effects of iron supplementation and anthelmintic treatment on motor and language development of preschool children in Zanzibar: Double blind, placebo controlled study. BMJ. 323 7326: 1389–1393.
  • Stoltzfus RJ, Chway HM, Montresor A, Tielsch JM, Jape JK, Albonico M, Savioli L. 2004. Low dose daily iron supplementation improves iron status and appetite but not anemia, whereas quarterly anthelminthic treatment improves growth, appetite and anemia in Zanzibari preschool children. J Nutr. 134 2: 348–356.
  • Toroyan T, Oakley A, Laing G, Roberts I, Mugford M, Turner J. 2004. The impact of day care on socially disadvantaged families: An example of the use of process evaluation within a randomized controlled trial. Child Care Health Dev. 30 6: 691–698.
  • Van Jaarsveld PJ, Faber M, Tanumihardjo SA, Nestel P, Lombard CJ, Benade AJ. 2005. Beta-carotene-rich orange-fleshed sweet potato improves the vitamin A status of primary school children assessed with the modified-relative-dose-response test. Am J Clin Nutr. 81 5: 1080–1087.
  • Van Stuijvenberg ME, Kvalsvig JD, Faber M, Kruger M, Kenoyer DG, Benade AJ. 1999. Effect of iron-, iodine-, and beta-carotene-fortified biscuits on the micronutrient status of primary school children: A randomized controlled trial. Am J Clin Nutr. 69 3: 497–503.
  • Van Stuijvenberg ME, Dhansay MA, Smuts CM, Lombard CJ, Jogessar VB, Benade AJ. 2001. Long-term evaluation of a micronutrient-fortified biscuit used for addressing micronutrient deficiencies in primary school children. Public Health Nutr. 4 6: 1201–1209.
  • Van Stuijvenberg ME, Smuts CM, Lombard CJ, Dhansay MA. 2008. Fortifying brown bread with sodium iron EDTA, ferrous fumarate, or electrolytic iron does not affect iron status in South African schoolchildren. J Nutr. 138 4: 782–786.
  • Van Teijlingen ER, Rennie AM, Hundley V, Graham W. 2001. The importance of conducting and reporting pilot studies: The example of the Scottish births survey. J Adv Nurs. 34 3: 289–295.
  • Venter CS, MacIntyre UE, Vorster HH. 2000. The development and testing of a food portion photograph book for use in an African population. J Hum Nutr Diet. 13 3: 205–218.
  • Victora CG, Habicht JP, Bryce J. 2004. Evidence-based public health: Moving beyond randomized trials. Am J Public Health. 94 3: 400–405.
  • Wegmuller R, Camara F, Zimmermann MB, Adou P, Hurrell F. 2006. Salt dual-fortified with iodine and micronized ground ferric pyrophosphate affects iron status but not haemoglobin in children in Cote d'Ivoire. J Nutr. 136 7: 1814–1820.
  • Williams CL, Strobino BA, Brotanek J. 2007. Weight control among obese adolescents: A pilot study. Int J Food Sci Nutr. 58 3: 217–230.
  • World Health Organization. 2007. WHOAnthro for personal computers, version 2, 2007 Manual: Software for assessing growth and development of the world's children. Geneva: WHO. http://www.who.int/childgrowth/software/en/ (accessed 13 June 2009).
  • World Health Organization. 2009. WHOAnthroPlus for Personal Computers Manual: Software for Assessing Growth of the World's Children and Adolescents. Geneva: WHO. Available online at: http://www.who.int/growthref/tools/en/ (accessed 13 June 2009).
  • Zimmermann MB. 2008. Methods to assess iron and iodine status. Br J Nutr. 99 Suppl 3: S2–S9.
  • Zimmermann MB, Connolly K, Bozo M, Bridson J, Rohner F, Grimci L. 2006. Iodine supplementation improves cognition in iodine-deficient schoolchildren in Albania: A randomized, controlled, double-blind study. Am J Clin Nutr. 83 1: 108–114.
  • Zlotkin SH, Tondeur M. 2007. Successful approaches: Sprinkles. In: Kraemer K, Zimmermann MB. editors. Nutritional Anemia. Basel, Switzerland: Sight and Life Press. p 269–283.

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