320
Views
7
CrossRef citations to date
0
Altmetric
PAPERS

Inclusion of a single-tail amino acid-based amphiphile in a lipoplex formulation: Effects on transfection efficiency and physicochemical properties

, , , , &
Pages 42-53 | Received 07 May 2010, Accepted 06 Jul 2010, Published online: 11 Jan 2011

References

  • Batra RK, Wangjohanning F, Wagner E, Garver RI, Curiel DT. 1994. Receptor-mediated gene delivery employing lectin-binding specificity. Gene Ther 1:255–260.
  • Bellare JR, Davis HT, Scriven LE, Talmon Y. 1988. Controlled environment vitrification system – an improved sample preparation technique. J Electron Microscopy Techn 10:87–111.
  • Choi JS, Nam K, Park J, Kim JB, Lee JK, Park J. 2004. Enhanced transfection efficiency of PAMAM dendrimer by surface modification with L-arginine. J Controlled Release 99:445–456.
  • Conner SD, Schmid SL. 2003. Regulated portals of entry into the cell. Nature 422:37–44.
  • Crystal RG. 1995. Transfer of genes to humans – early lessons and obstacles to success. Science 270:404–410.
  • Cui H, Hodgdon TK, Kaler EW, Abezgauz L, Danino D, Lubovsky M, Talmon Y, Pochan DJ. 2007. Elucidating the assembled structure of amphiphiles in solution via cryogenic transmission electron microscopy. Soft Matter 3:945.
  • de Lima MCP, Simoes S, Pires P, Faneca H, Duzgunes N. 2001. Cationic lipid-DNA complexes in gene delivery: From biophysics to biological applications. Adv Drug Del Rev 47:277–294.
  • Edelstein ML, Abedi MR, Wixon J. 2007. Gene therapy clinical trials worldwide to 2007 – an update. J Gene Med 9:833–842.
  • Faneca H, Faustino A, De Lima MCP. 2008. Synergistic antitumoral effect of vinblastine and HSV-Tk/GCV gene therapy mediated by albumin-associated cationic liposomes. J Contr Release 126:175–184.
  • Faneca H, Simoes S, de Lima MCP. 2004. Association of albumin or protamine to lipoplexes: Enhancement of transfection and resistance to serum. J Gene Med 6:681.
  • Felgner JH, Kumar R, Sridhar CN, Wheeler CJ, Tsai YJ, Border R, Ramsey P, Martin M, Felgner PL. 1994. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem 269:2550–2561.
  • Fonseca SB, Pereira MP, Kelley SO. 2009. Recent advances in the use of cell-penetrating peptides for medical and biological applications. Adv Drug Del Rev 61:953–964.
  • Gustafsson J, Orädd G, Almgren M. 1997a. Disintegration of the lecithin lamellar phase by cationic surfactants. Langmuir 13:6956–6963.
  • Gustafsson J, Orädd G, Lindblom G, Olsson U, Almgren M. 1997b. A defective swelling lamellar phase. Langmuir 13:852–860.
  • Huebner S, Battersby BJ, Grimm R, Cevc G. 1999. Lipid-DNA complex formation: Reorganization and rupture of lipid vesicles in the presence of DNA as observed by cryoelectron microscopy. Biophys J 76:3158–3166.
  • Israelachvili JN, Mitchell DJ, Ninham BW. 1976. Theory of self-assembly of hydrocarbon amphiphiles into micelles and bilayers. J Chem Soc Faraday Trans II 72:1525–1568.
  • Koltover I, Salditt T, Radler JO, Safinya CR. 1998. An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery. Science 281:78–81.
  • Konopka K, Pretzer E, Felgner PL, Duzgunes N. 1996. Human immunodeficiency virus type-1 (HIV-1) infection increases the sensitivity of macrophages and THP-1 cells to cytotoxicity by cationic liposomes. Biochim Biophys Acta – Molec Cell Res 1312:186–196.
  • Koynova R, MacDonald RC. 2007. Natural lipid extracts and biomembrane-mimicking lipid compositions are disposed to form nonlamellar phases, and they release DNA from lipoplexes most efficiently. Biochim Biophys Acta – Biomembranes 1768:2373–2382.
  • Koynova R, Wang L, MacDonald RC. 2006. An intracellular lamellar-nonlamellar phase transition rationalizes the superior performance of some cationic lipid transfection agents. Proc Nat Acad Sci USA 103:14373–14378.
  • Koynova R, Wang L, Tarahovsky Y, MacDonald RC. 2005. Lipid phase control of DNA delivery. Bioconjugate Chem 16:1335–1339.
  • Lasic DD, Strey H, Stuart MCA, Podgornik R, Frederik PM. 1997. The structure of DNA-liposome complexes. J Am Chem Soc 119:832–833.
  • Lasic DD, Templeton NS. 1996. Liposomes in gene therapy. Adv Drug Deliv Rev 20:221–266.
  • Lechardeur D, Verkman AS, Lukacs GL. 2005. Intracellular routing of plasmid DNA during non-viral gene transfer. Adv Drug Del Rev 57:755–767.
  • Lundberg D, Ljusberg-Wahren H, Norlin A, Holmberg K. 2004. Studies on dodecyl betainate in combination with its degradation products or with phosphatidyl choline-phase behavior and hemolytic activity. J Colloid Interface Sci 278:478–487.
  • Morán C, Clapes P, Comelles F, Garcia T, Perez L, Vinardell P, Mitjans M, Infante MR. 2001. Chemical structure/property relationship in single-chain arginine surfactants. Langmuir 17:5071–5075.
  • Patel LN, Zaro JL, Shen WC. 2007. Cell penetrating peptides: Intracellular pathways and pharmaceutical perspectives. Pharm Res 24:1977–1992.
  • Patil SD, Rhodes DG, Burgess DJ. 2005. DNA-based therapeutics and DNA delivery systems: A comprehensive review. AAPS J 7:E61–77.
  • Pinnaduwage P, Schmitt L, Huang L. 1989. Use of a quaternary ammonium detergent in liposome mediated DNA transfection of mouse L-cells. Biochim Biophys Acta 985:33–37.
  • Pozzi D, Caracciolo G, Caminiti R, De Sanctis SC, Amenitsch H, Marchini C, Montani M, Amici A. 2009. Toward the rational design of lipid gene vectors: Shape coupling between lipoplex and anionic cellular lipids controls the phase evolution of lipoplexes and the efficiency of DNA release. ACS Appl Mater Interfaces 1:2237–2249.
  • Provencher SW. 1979. Inverse problems in polymer characterization – direct analysis of polydispersity with photon correlation spectroscopy. Macromol Chem Phys 180:201–209.
  • Provencher SW. 1982. Contin – a general-purpose constrained regularization program for inverting noisy linear algebraic and integral-equations. Comp Phys Comm 27:229–242.
  • Rädler JO, Koltover I, Salditt T, Safinya CR. 1997. Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science 275:810–814.
  • Reddy JA, Low PS. 2000. Enhanced folate receptor mediated gene therapy using a novel pH-sensitive lipid formulation. J Contr Release 64:27–37.
  • Rejman J, Oberle V, Zuhorn IS, Hoekstra D. 2004. Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis. Biochem J 377:159–169.
  • Rosa M, Penacho N, Simoes S, Lima MCP, Lindman B, Miguel MG. 2008. DNA pre-condensation with an amino acid-based cationic amphiphile. A viable approach for liposome-based gene delivery. Mol Membr Biol 25:23–34.
  • Rubanyi GM. 2001. The future of human gene therapy. Mol Aspects Med 22:113–142.
  • Schmutz M, Durand D, Debin A, Palvadeau Y, Etienne A, Thierry AR. 1999. DNA packing in stable lipid complexes designed for gene transfer imitates DNA compaction in bacteriophage. Proc Nat Acad Sci USA 96:12293–12298.
  • Scott GD, Kilgour DM. 1969. Density of random close packing of spheres. J Phys D-Appl Phys 2:863–866.
  • Simberg D, Danino D, Talmon Y, Minsky A, Ferrari ME, Wheeler CJ, Barenholz Y. 2001. Phase behavior, DNA ordering, and size instability of cationic lipoplexes – relevance to optimal transfection activity. J Biol Chem 276:47453–47459.
  • Simões S, Filipe A, Faneca H, Mano M, Penacho N, Düzgünes N, de Lima MCP. 2005. Cationic liposomes for gene delivery. Expert Opin Drug Deliv 2:237–254.
  • Simões S, Pires P, Duzgunes N, de Lima MCP. 1999. Cationic liposomes as gene transfer vectors: Barriers to successful application in gene therapy. Curr Opin Mol Ther 1:147–157.
  • Simoes S, Slepushkin V, Duzgunes N, de Lima MCP. 2001. On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes. Biochim Biophys Acta – Biomembranes 1515:23–37.
  • Simões S, Slepushkin V, Pires P, Gaspar R, de Lima MCP, Duzgunes N. 1999. Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides. Gene Ther 6:1798.
  • Smisterova J, Wagenaar A, Stuart MCA, Polushkin E, ten Brinke G, Hulst R, Engberts JBFN, Hoekstra D. 2001. Molecular shape of the cationic lipid controls the structure of cationic lipid/dioleylphosphatidylethanolamine-DNA complexes and the efficiency of gene delivery. J Biol Chem 276:47615–47622.
  • Štěpánek P. 1993. In: Brown W, editor. Dynamic light scattering: The method and some applications. Oxford, UK: Oxford University Press.
  • Stewart KM, Horton KL, Kelley SO. 2008. Cell-penetrating peptides as delivery vehicles for biology and medicine. Org Biomol Chem 6:2242–2255.
  • Templeton NS, Lasic DD. 1999. New directions in liposome gene delivery. Mol Biotechnol 11:175–180.
  • Thompson RA, Allenmark S. 1989. Effects of molecular association on the rates of hydrolysis of long-chain alkyl betainates (alkoxycarbonyl-N,N,N-trialkylmethanaminium halides). Acta Chem Scand 43:690–693.
  • Ulmius J, Wennerström H. 1977. Proton NMR bandshapes for large aggregates – micellar solutions of hexadecyltrimethylammonium bromide. J Magn Reson 28:309.
  • Ulrich AS. 2002. Biophysical aspects of using liposomes as delivery vehicles. Biosci Rep 22:129–150.
  • Wagner E, Curiel D, Cotten M. 1994. Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis. Adv Drug Del Rev 14:113–135.
  • Wiethoff CM, Middaugh CR. 2003. Barriers to nonviral gene delivery. J Pharmaceut Sci 92:203–217.
  • Xu YH, Hui SW, Frederik P, Szoka FC. 1999. Physicochemical characterization and purification of cationic lipoplexes. Biophys J 77:341–353.
  • Zuhorn IS, Bakowsky U, Polushkin E, Visser WH, Stuart MCA, Engberts JBFN, Hoekstra D. 2005. Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection efficiency. Mol Ther 11:801–810.
  • Zuhorn IS, Engberts JBFN, Hoekstra D. 2007. Gene delivery by cationic lipid vectors: Overcoming cellular barriers. Eur Biophys J 36:349–362.
  • Zuhorn IS, Hoekstra D. 2002. On the mechanism of cationic amphiphile-mediated transfection. To fuse or not to fuse: Is that the question? J Membr Biol 189:167–179.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.