1,406
Views
43
CrossRef citations to date
0
Altmetric
Research Article

The substrate specificity of the human ADP/ATP carrier AAC1

, , , , , & show all
Pages 160-168 | Received 30 Aug 2012, Accepted 17 Oct 2012, Published online: 23 Nov 2012

References

  • Andersen HC. 1983. A “velocity” version of the Shake algorithm for molecular dynamics calculations. J Comput Phys 52:24–34.
  • Brustovetsky N, Bamberg E, Gropp T, Klingenberg M. 1997. Biochemical and physical parameters of the electrical currents measured with the ADP/ATP carrier by photolysis of caged ADP and ATP. Biochemistry 36:13865–13872.
  • Brustovetsky N, Becker A, Klingenberg M, Bamberg E. 1996. Electrical currents associated with nucleotide transport by the reconstituted mitochondrial ADP/ATP carrier. Proc Natl Acad Sci USA 93:664–668.
  • Dalbon P, Brandolin G, Boulay F, Hoppe J, Vignais PV. 1988. Mapping of the nucleotide-binding sites in the ADP/ATP carrier of beef heart mitochondria by photolabeling with 2-azido[alpha-32P]adenosine diphosphate. Biochemistry 27:5141–5149.
  • Darden T, York D, Pederson L. 1993. Article mesh Ewald: An Nlog(N) method for Ewald sums in large systems. J Chem Phys 98:10089–10092.
  • De Marcos Lousa C, Trézéguet V, Dianoux AC, Brandolin G, Lauquin GJ. 2002. The human mitochondrial ADP/ATP carriers: Kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae. Biochemistry 41:14412–14420.
  • Dehez F, Pebay-Peyroula E, Chipot C. 2008. Binding of ADP in the mitochondrial ADP/ATP carrier is driven by an electrostatic funnel. J Am Chem Soc 130:12725–12733.
  • Dianoux AC, Noel F, Fiore C, Trézéguet V, Kieffer S, Jaquinod M, 2000. Two distinct regions of the yeast mitochondrial ADP/ATP carrier are photolabeled by a new ADP analogue: 2-azido-3′-O-naphthoyl-[beta-32P]ADP. Identification of the binding segments by mass spectrometry. Biochemistry 39:11477–11487.
  • Dolce V, Scarcia P, Iacopetta D, Palmieri F. 2005. A fourth ADP/ATP carrier isoform in man: Identification, bacterial expression, functional characterization and tissue distribution. FEBS Lett 579:633–637.
  • Driessen AJ, de Vrij W, Konings WN. 1985. Incorporation of beef heart cytochrome c oxidase as a proton-motive force-generating mechanism in bacterial membrane vesicles. Proc Natl Acad Sci USA 82:7555–7559.
  • Duée ED, Vignais PV. 1968. Atracyloside-sensitive translocation of phosphonic acid analogues of adenine nucleotides in mitochondria. Biochem Biophys Res Commun 30:546–553.
  • Feller SE, Mackerell AD Jr. 2000. All-atom empirical force field for nucleic acids: I. Parameter optimization based on small molecule and condensed phase macromolecular target data. J Phys Chem B104:7510–7515.
  • Heidkamper D, Müller V, Nelson DR, Klingenberg M. 1996. Probing the role of positive residues in the ADP/ATP carrier from yeast. The effect of six arginine mutations on transport and the four ATP versus ADP exchange modes. Biochemistry 35:16144–16152.
  • Hénin J, Shinoda W, Klein ML. 2008. United-atom acyl chains for CHARMM phospholipids. J Phys Chem B 112:7008–7015.
  • Humphrey W, Dalke A, Schulten K. 1996. VMD – visual molecular dynamics. J Mol Graphics 97:25–27.
  • Jasien P, Fitzgerald G. 1990. Molecular dipole moments and polarizabilities from local density functional calculations: Application to DNA base pairs. J Chem Phys 93:2554.
  • Klingenberg M. 2008. The ADP and ATP transport in mitochondria and its carrier. Biochim Biophys Acta 1778:1978–2021.
  • Krämer R, Klingenberg M. 1980. Enhancement of reconstituted ADP, ATP exchange activity by phosphatidylethanolamine and by anionic phospholipids. FEBS Lett 119:257–260.
  • Krammer EM, Ravaud S, Dehez F, Frelet-Barrand A, Pebay-Peyroula E, Chipot C. 2009. High-chloride concentrations abolish the binding of adenine nucleotides in the mitochondrial ADP/ATP carrier family. Biophys J 97:L25–L27.
  • Kunji ER. 2004. The role and structure of mitochondrial carriers. FEBS Lett 564:239–244.
  • Kunji ER, Slotboom DJ, Poolman B. 2003. Lactococcus lactis as host for overproduction of functional membrane proteins. Biochim Biophys Acta 1610:97–108.
  • Mackerell AD Jr, Bashford D, Bellott M, Dunbrack RL, Evanseck JD, Field MJ, 1998. All-atom empirical potential for molecular modeling and dynamics studies of proteins. J Phys Chem B102:3586–3616.
  • Mackerell AD Jr, Feig M, Brooks CL 3rd. 2004. Extending the treatment of backbone energetics in protein force fields: Limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations. J Comput Chem 25:1400–1415.
  • Miroux B, Walker JE. 1996. Over-production of proteins in Escherichia coli: Mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels. J Mol Biol 260:289–298.
  • Monne M, Chan KW, Slotboom DJ, Kunji ER. 2005. Functional expression of eukaryotic membrane proteins in Lactococcus lactis. Protein Sci 14:3048–3056.
  • Müller V, Heidkamper D, Nelson DR, Klingenberg M. 1997. Mutagenesis of some positive and negative residues occurring in repeat triad residues in the ADP/ATP carrier from yeast. Biochemistry 36:16008–16018.
  • Nury H, Dahout-Gonzalez C, Trézéguet V, Lauquin GJ, Brandolin G, Pebay-Peyroula E. 2006. Relations between structure and function of the mitochondrial ADP/ATP carrier. Annu Rev Biochem 75:713–741.
  • Palmieri F. 2004. The mitochondrial transporter family (SLC25): Physiological and pathological implications. Pflugers Arch 447:689–709.
  • Pebay-Peyroula E, Dahout-Gonzalez C, Kahn R, Trézéguet V, Lauquin GJ, Brandolin G. 2003. Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature 426:39–44.
  • Pfaff E, Klingenberg M. 1968. Adenine nucleotide translocation of mitochondria. 1. Specificity and control. Eur J Biochem 6:66–79.
  • Phillips JC, Braun R, Wang W, Gumbart J, Tajkhorshid E, Villa E, 2005. Scalable molecular dynamics with NAMD. J Comput Chem 26:1781–1802.
  • Ravaud S, Bidon-Chanal A, Blesneac I, Machillot P, Juillan-Binard C, Dehez F, 2012. Impaired transport of nucleotides in a mitochondrial carrier explains severe human genetic diseases. ACS Chem Biol 7:1164–1169.
  • Robinson AJ, Kunji ER. 2006. Mitochondrial carriers in the cytoplasmic state have a common substrate binding site. Proc Natl Acad Sci USA 103:2617–2622.
  • Robinson AJ, Overy C, Kunji ER. 2008. The mechanism of transport by mitochondrial carriers based on analysis of symmetry. Proc Natl Acad Sci USA 105:17766–17771.
  • Tuckerman M, Berne BJ, Martyna GJ. 1992. Reversible multiple time scale molecular dynamics. J Chem Phys 97:1990–1999.
  • Wang Y, Tajkhorshid E. 2008. Electrostatic funneling of substrate in mitochondrial inner membrane carriers. Proc Natl Acad Sci USA 105:9598–9603.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.