Enhanced 2-phenylethanol production from L-phenylalanine via in situ product adsorption

References

• Albertazzi E, Cardillo R, Servi S, Zucchi G. 1994. Biogeneration of 2-phenylethanol and 2-phenylethylacetate important aroma components. Biotechnol Lett 16:491–496.
   Google Scholar
• Bruce LJ, Daugulis AJ. 1991. Solvent selection strategies for extractive biocatalysis. Biotechnol Progr 7:116–124.
   PubMed Web of Science ®Google Scholar
• Ehrlich F. 1907. Über die Bedingungen der Fuselölbildung und über ihren Zusammenhang mit dem Eiweiβaufbau der Hefe. Ber Dtsch Chem Ges 40:1027–1047.
   Google Scholar
• Eshkol N, Sendovski M, Bahalul M, Katz-Ezov T, Kashi Y, Fishman A. 2009. Production of 2-phenylethanol from L-phenylalanine by a stress tolerant Saccharomyces cerevisiae strain. J Appl Microbiol 106:534–542.
   PubMed Web of Science ®Google Scholar
• Etschmann MMW, Bluemke W, Sell D, Schrader J. 2002. Biotechnological production of 2-phenylethanol. Appl Microbiol Biotechnol 59:1–8.
   PubMed Web of Science ®Google Scholar
• Etschmann MMW, Schrader J. 2006. An aqueous-organic two-phase bioprocess for efficient production of the natural aroma chemicals 2-phenylethanol and 2-phenylethylacetate with yeast. Appl Microbiol Biotechnol 71:440–443.
   PubMed Web of Science ®Google Scholar
• Etschmann MMW, Sell D, Schrader J. 2003. Screening of yeasts for the production of the aroma compound 2-phenylethanol in a molasses-based medium. Biotechnol Lett 25:531–536.
   PubMed Web of Science ®Google Scholar
• Etschmann MMW, Sell D, Schrader J. 2004. Medium optimization for the production of the aroma compound 2-phenylethanol using a genetic algorithm. J Mol Catal B: Enzymatic 29:187–193.
   Google Scholar
• Fabre CE, Blanc PJ, Goma G. 1998. Production of 2-phenylethyl alcohol by Kluyveromyces marxianus. Biotechnol Prog 14:270–274.
   PubMed Web of Science ®Google Scholar
• Gao F, Daugulis AJ. 2009. Bioproduction of the aroma compound 2-phenylethanol in a solid-liquid two-phase partitioning bioreactor system by Kluyveromyces marxianus. Biotechnol Bioeng 104:332–339.
   PubMed Web of Science ®Google Scholar
• Garavaglia J, Flôres SH, Pizzolato TM, Peralba MC, Ayub MAZ. 2007. Bioconversion of L-phenylalanine into 2-phenylethanol by Kluyveromyces marxianus in grape must cultures. World J Microbiol Biotechnol 23:1273–1279.
   Web of Science ®Google Scholar
• Hua DL, Ma CQ, Lin S, Song LF, Deng ZX, Maomy Z, Zhang ZB, Yu B, Xu P. 2007a. Biotransformation of isoeugenol to vanillin by a newly isolated Bacillus pumilus strain: identification of major metabolites. J Biotechnol 130:463–470.
   PubMed Web of Science ®Google Scholar
• Hua DL, Ma CQ, Song LF, Lin S, Zhang ZB, Deng ZX, Xu P. 2007b. Enhanced vanillin production from ferulic acid using adsorbent resin. Appl Microbiol Biotechnol 74:783–790.
   PubMed Web of Science ®Google Scholar
• Huang CJ, Lee SL, Chou CC. 2000. Production and molar yield of 2-phenylethanol by Pichia fermentans L-5 as affected by some medium components. J Biosci Bioeng 90:142–147.
   PubMed Web of Science ®Google Scholar
• Huang CJ, Lee SL, Chou CC. 2001. Production of 2-phenylethanol, a flavor ingredient, by Pichia fermentans L-5 under various culture conditions. Food Res Int 34:277–282.
   Web of Science ®Google Scholar
• Lester G. 1965. Inhibition of growth, synthesis, and permeability in Neurospora crassa by phenethyl alcohol. J Bacteriol 90:29–37.
   Google Scholar
• Lu J, Zhang WG. 2008. Production of 2-phenylethanol from L-phenylalanine by bioconversion in biphasic system. Chem Ind Eng Progr 27:417–420.
   Google Scholar
• Mei JF, Min H, Lü ZM. 2009. Enhanced biotransformation of L-phenylalanine to 2-phenylethanol using an in situ product adsorption technique. Process Biochem 44:886–890.
   Web of Science ®Google Scholar
• Serp D, von Stockar U, Marison IW. 2003. Enhancement of 2-phenylethanol productivity by Saccharomyces cerevisiae in two-phase fed-batch fermentation using solvent immobilization. Biotechnol Bioeng 82:103–110.
   PubMed Web of Science ®Google Scholar
• Seward R, Willetts JM, Dinsdale MG, Lloyd D. 1996. The effects of ethanol, hexan-1-ol, and 2-phenylethanol on cider yeast growth, viability, and energy status; synergistic inhibition. J Inst Brew 102:439–443.
   Google Scholar
• Stark D, Münch T, Sonnleitner B, Marison IW, von Stockar U. 2002. Extractive bioconversion of 2-phenylethanol from L-phenylalanine by Saccharomyces cerevisiae. Biotechnol Progr 18:514–523.
   PubMed Web of Science ®Google Scholar
• Stark D, Zala D, Münch T, Sonnleitner B, Marison IW, von Stockar U. 2003. Inhibition aspects of the bioconversion of L-phenylalanine to 2-phenylethanol by Saccharomyces cerevisiae. Enzym Microbial Technol 32:212–223.
   Web of Science ®Google Scholar
• Wittmann C, Hans M, Bluemke W. 2002. Metabolic physiology of aroma-producing Kluyveromyces marxianus. Yeast 19:1351–1363.
   PubMed Web of Science ®Google Scholar
• Xu P, Hua DL, Ma CQ. 2007a. Microbial transformation of propenylbenzenes for natural flavour production. Trends Biotechnol 25:571–576.
   PubMed Web of Science ®Google Scholar
• Xu P, Qiu JH, Zhang YN, Chen J, Wang PG, Yan B, Song J, Xi RM, Deng ZX, Ma CQ. 2007b. Efficient whole-cell biocatalytic synthesis of N-acetyl-D-neuraminic acid. Adv Synth Catal 349:1614–1618.
   Web of Science ®Google Scholar
• Yoon SH, Lee EG, Das A, Lee SH, Li C, Ryu HK, Choi MS, Seo WT, Kim SW. 2008. Enhanced vanillin production from recombinant E. coli using NTG mutagenesis and adsorbent resin. Biotechnol Progr 23:1143–1148.
   Google Scholar