109
Views
2
CrossRef citations to date
0
Altmetric
Research Article

Modeling and optimization of lipase-catalyzed esterification of policosanols with conjugated linoleic acid by response surface methodology

, , , &
Pages 114-122 | Received 22 Oct 2012, Accepted 06 Feb 2013, Published online: 25 Mar 2013

References

  • Adhikari P, Hwang KT, Park JN, Kim CK. 2006. Policosanol content and composition in perilla seeds. J Agr Food Chem 54:5359–5362.
  • Arruzazabala ML, Molina V, Mas R, Fernandez L, Carbajal D, Valdes S, Gladys C. 2002. Antiplatelet effects of policosanol (20 and 40 mg/day) in healthy volunteers and dyslipidaemic patients. Clin Exp Pharmacol Physiol 29: 891–897.
  • Arruzazabala ML, Carbajal D, Mas R, Molina V, Valdes S, Laguna A. 1994. Cholesterol lowering effects of policosanol in rabbits. Biol Res 27:205–208.
  • Blankson H, Stakkestad JA, Fagertun H, Thom E, Wadstein J, Gudmundsen O. 2000. Conjugated linoleic acid reduces body fat mass in overweight and obese humans. J Nutrition 130: 2943–2948.
  • Bocca C, Bozzo F, Cannito S, Colombatto S, Miglietta A. 2010. CLA reduces breast cancer cell growth and invasion through ERalpha and PI3K/Akt pathways. Chem-biol Interact 183: 187–193.
  • Kim BH, Akoh CC. 2007. Modeling and optimization of lipase-catalyzed synthesis of phytosteryl esters of oleic acid by response surface methodology. Food Chem 102: 336–342.
  • Erbeldinger M, Ni X, Halling PJ. 1998. Enzymatic synthesis with mainly undissolved substrates at very high concentrations. Enzyme Microb Tech 23:141–148.
  • Flintoff-Dye NL, Omaye ST. 2005. Antioxidant effects of conjugated linoleic acid isomers in isolated human low-density lipoproteins. Nutr Res 25:1–12.
  • Garcia HS, Keough KJ, Arcos JA, Hill CG. 1999. Continuous interesterification of butteroil and conjugated linoleic acid in a tubular reactor packed with an immobilized lipase. Biotechnol Tech 13:369–373.
  • Gorreta F, Bernasconi R, Galliani G, Salmona M, Tacconi MT, Bianchi R. 2002. Wax esters of n-3 polyunsaturated fatty acids: A new stable formulation as a potential food supplement. 1-Digestion and Absorption in Rats. LWT. Food Sci Tech 35:458–465.
  • Gunawan S, Vali SR, Ju Y-H. 2006. Purification and identification of rice bran oil fatty acid steryl and wax esters. J Am Oil Chem Soc 83:449–456.
  • Harrabi S, Boukhchina S, Mayer PM, Kallel H. 2009. Policosanol distribution and accumulation in developing corn kernels. Food Chem 115:918–923.
  • Hansen IA, Mead JF. 1965. The fate of dietary wax esters in the rat. Proc Soc Exp Biol Med 120:527–532.
  • Hwang KT, Kim JE, Weller CL. 2005. Policosanol contents and compositions in wax-like materials extracted from selected cereals of Korean origin. Cereal Chem 82:242–245.
  • Irmak S, Dunford NT, Milligan J. 2006. Policosanol contents of beeswax, sugar cane and wheat extracts. Food Chem 95:312–318.
  • Kabir Y, Kimura S. 1995. Tissue distribution of (8-14C)- octacosanol in liver and muscle of rats after serial administration. Nutr Metab 39:279–284.
  • Kelly GS. 2001. Conjugated linoleic acid: a review. Altern Med Rev 6:367–382.
  • Stusser R, Batista J, Padron R, Sosa F, Pereztol O. 1998. Long-term therapy with policosanol improves treadmill exercise- ECG testing performance of coronary heart disease patients. Int J Clin Pharmacol Ttherapeut 36:469–473.
  • Taylor JC, Rapport L, Lockwood GB. 2003. Octacosanol in human health. Nutrition 19:192–195.
  • Vali SR, Ju Y-H, Kaimal TNB, Chern Y-T. 2005. A process for the preparation of food-grade rice bran wax and the determination of its composition. J Am Oil Chem Soc 82:57–64.
  • Verschuren PM, Nugteren DH. 1989. Evaluation of jojoba oil as a low-energy fat. 2. Intestinal transit time, stomach emptying and digestibility in short-term feeding studies in rats. Food Chem Toxicol 27:45–48.
  • Wahle KWJ, Heys SD, Rotondo D. 2004. Conjugated linoleic acids: are they beneficial or detrimental to health? Prog Lipid Res 43:553–587.
  • Yaron A, Samoiloff V, Benzioni A. 1982. Absorption and distribution of orally administered jojoba wax in mice. Lipids 17:169–171.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.