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Short Communication

Systemic and intrahippocampal administrations of the glucocorticoid receptor antagonist RU38486 impairs fear memory reconsolidation in rats

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Pages 459-464 | Received 13 Aug 2010, Accepted 10 Dec 2010, Published online: 27 Mar 2011

References

  • Abrari K, Rashidy-Pour A, Semnanian S, Fathollahi Y. 2008. Administration of corticosterone after memory reactivation disrupts subsequent retrieval of a contextual conditioned fear memory: Dependence upon training intensity. Neurobiol Learn Mem. 89:178–184.
  • Alberini CM. 2005. Mechanisms of memory stabilization: Are consolidation and reconsolidation similar or distinct processes?. Trends Neurosci. 28:51–56.
  • Amaral OB, Luft T, Cammarota M, Izquierdo I, Roesler R. 2007. Temporary inactivation of the dorsal hippocampus induces a transient impairment in retrieval of aversive memory. Behav Brain Res. 180:113–118.
  • Debiec J, LeDoux JE, Nader K. 2002. Cellular and systems reconsolidation in the Hippocampus. Neuron. 36:527–538.
  • De Kloet ER, Vreugdenhil E, Oitzl MS, Joëls M. 1998. Brain corticosteroid receptor balance in health and disease. Endocr Rev. 19:269–301.
  • Duvarci S, Nader K. 2004. Characterization of fear memory reconsolidation. J Neurosci. 24:9269–9275.
  • Eisenberg M, Kobilo T, Berman DE, Dudai Y. 2003. Stability of retrieved memory: Inverse correlation with trace dominance. Science. 301:1102–1104.
  • Joels M, de Kloet ER. 1992. Control of neuronal excitability by corticosteroid hormones. Trends Neurosci. 15:25–30.
  • Khaksari M, Rashidy-Pour A, Vafaei AA. 2007. Central mineralocorticoid receptors are indispensable for corticosterone-induced impairment of memory retrieval in rats. Neuroscience. 149:729–738.
  • Kindt M, Soeter M, Vervliet B. 2009. Beyond extinction: Erasing human fear responses and preventing the return of fear. Nat Neurosci. 12:256–258.
  • Luft T, Amaral OB, Schwartsmann G, Roesler R. 2008. Transient disruption of fear-related memory by post-retrieval inactivation of gastrin-releasing peptide or N-methyl-d-aspartate receptors in the hippocampus. Curr Neurovasc Res. 5:21–27.
  • Mao J, Regelson W, Kalimi M. 1992. Molecular mechanisms of RU 486 action: A review. Mol Cell Biol. 109:1–8.
  • McGaugh JL. 2000. Memory-a century of consolidation. Science. 287:248–251.
  • Nader K, Einarsson EO. 2010. Memory reconsolidation: An update. Ann NY Acad Sci. 1191:27–41.
  • Oitzl MS, de Kloet ER. 1992. Selective corticosteroid antagonists modulates specific aspects of spatial orientation learning. Behav Neurosci. 106:62–71.
  • Pakdel R, Rashidy-Pour A. 2006. Glucocorticoid-induced impairment of long-term memory retrieval in rats: An interaction with dopamine D2 receptors. Neurobiol Learn Mem. 85:300–306.
  • Paxinos G, Watson C. 1998. The rat brain in stereotaxic coordinates . 4th ed. Orlando, FL: Academic Press.
  • Paxinos G, Watson C. 2005. The rat brain in stereotaxic coordinates . 5th ed. Orlando, FL: Academic Press.
  • Quevedo J, Vianna MRM, Roesler R, de Paris F, Izquierdo I, Rose SPR. 1999. Two time windows of anisomycin-induced amnesia for inhibitory avoidance training in rats: Protection from amnesia by pretraining but not pre-exposure to the task apparatus. Learn Mem. 6:600–607.
  • Roozendaal B. 2000. Glucocorticoids and regulation of memory consolidation. Psychoneuroendocrinology. 25:213–238.
  • Roozendaal B, McGaugh JL. 1997. Glucocorticoid receptor agonist and antagonist administration into the basolateral but not central amygdala modulates memory storage. Neurobiol Learn Mem. 67:176–179.
  • Sajadi AA, Samaei SA, Rashidy-Pour A. 2006. Intra-hippocampal microinjections of anisomycin did not block glucocorticoid-induced impairment of memory retrieval in rats: An evidence for non-genomic effects of glucocorticoids. Behav Brain Res. 173:158–162.
  • Schelling G, Roozendaal B, de Quervain DJ. 2004. Can posttraumatic stress disorder prevented with glucocorticoids?. Ann NY Acad Sci. 1032:158–166.
  • Suzuki A, Josselyn SA, Frankland P, Masushige S, Silva AJ, Kida S. 2004. Memory reconsolidation and extinction have distinct temporal and biochemical signatures. J Neurosci. 24:4787–4795.
  • Taubenfeld SM, Riceberg JS, New AS, Alberini CM. 2009. Preclinical assessment for selectively disrupting a traumatic memory via postretrieval inhibition of glucocorticoid receptors. Biol Psychiatry. 65:249–257.
  • Tronel S, Alberini CM. 2007. Persistent disruption of a traumatic memory by post-retrieval inactivation of glucocorticoid receptors in the amygdala. Biol Psychiatry. 62:33–39.
  • Yudt MR, Cidlowski JA. 2002. The glucocorticoid receptor: Coding a diversity of proteins and responses through a single gene. Mol Endocrinol. 16:1719–1726.

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