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Stress
The International Journal on the Biology of Stress
Volume 18, 2015 - Issue 1
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Original Research Report

Role of the dorsomedial hypothalamus in glucocorticoid-mediated feedback inhibition of the hypothalamic–pituitary–adrenal axis

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Pages 76-87 | Received 25 Jun 2014, Accepted 21 Dec 2014, Published online: 17 Feb 2015

References

  • Anseloni VC, He F, Novikova SI, Turnbach RM, Lidow IA, Ennis M, Lidow MS. (2005). Alterations in stress-associated behaviors and neurochemical markers in adult rats after neonatal short-lasting local inflammatory insult. Neuroscience 131:635–45
  • Bailey TW, DiMicco JA. (2001). Chemical stimulation of the dorsomedial hypothalamus elevates plasma ACTH in conscious rats. Am J Physiol Regul Integr Comp Physiol 280:R8–15
  • Bernardis LL, Bellinger LL. (1998). The dorsomedial hypothalamic nucleus revisited: 1998 update. Proc Soc Exp Biol Med 218:284–306
  • Boudaba C, Szabo K, Tasker JG. (1996). Physiological mapping of local inhibitory inputs to the hypothalamic paraventricular nucleus. J Neurosci 16:7151–60
  • Cnaan A, Laird NM, Slasor P. (1997). Using the general linear mixed model to analyse unbalanced repeated measures and longitudinal data. Stat Med 16:2349–80
  • Cole MA, Kim PJ, Kalman BA, Spencer RL. (2000). Dexamethasone suppression of corticosteroid secretion: evaluation of the site of action by receptor measures and functional studies. Psychoneuroendocrinology 25:151–67
  • Dallman MF, Akana SK, Cascio CS, Darlington DN, Jacobson L, Levin N. (1987). Regulation of ACTH secretion: variations on a theme of B. Recent Prog Horm Res 43:113–73
  • de Bortoli VC, Yamashita PS, Zangrossi H Jr. (2013). 5-HT1A and 5-HT2A receptor control of a panic-like defensive response in the rat dorsomedial hypothalamic nucleus. J Psychopharmacol 27:1116–23
  • DiMicco JA, Samuels BC, Zaretskaia MV, Zaretsky DV. (2002). The dorsomedial hypothalamus and the response to stress: part renaissance, part revolution. Pharmacol Biochem Behav 71:469–80
  • Diorio D, Viau V, Meaney MJ. (1993). The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress. J Neurosci 13:3839–47
  • Dupouy JP, Chatelain A, Godaut M. (1980). Influences of heparin on ACTH distribution and immunoreactivity in plasma of the rat. In vivo and in vitro studies. J Physiol (Paris) 76:631–5
  • Evanson NK, Tasker JG, Hill MN, Hillard CJ, Herman JP. (2010). Fast feedback inhibition of the HPA axis by glucocorticoids is mediated by endocannabinoid signaling. Endocrinology 151:4811–19
  • Feng N, Lowry CA, Lukkes JL, Orchinik M, Forster GL, Renner KJ. (2010). Organic cation transporter inhibition increases medial hypothalamic serotonin under basal conditions and during mild restraint. Brain Res 1326:105–13
  • Feng N, Telefont M, Kelly K, Orchinik M, Forster GL, Renner KJ, Lowry CA. (2009). Local perfusion of corticosterone in the rat medial hypothalamus potentiates D-fenfluramine-induced elevations of extracellular 5-HT concentrations. Horm Behav 56:149–57
  • Fontes MA, Xavier CH, de Menezes RC, DiMicco JA. (2011). The dorsomedial hypothalamus and the central pathways involved in the cardiovascular response to emotional stress. Neuroscience 184:64–74
  • Furay AR, Bruestle AE, Herman JP. (2008). The role of the forebrain glucocorticoid receptor in acute and chronic stress. Endocrinology 149:5482–90
  • Gasser PJ, Lowry CA, Orchinik M. (2006). Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organic cation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci 26:8758–66
  • Gasser PJ, Orchinik M, Raju I, Lowry CA. (2009). Distribution of organic cation transporter 3, a corticosterone-sensitive monoamine transporter, in the rat brain. J Comp Neurol 512:529–55
  • Goebel M, Stengel A, Wang L, Reeve J, Jr Tache Y. (2011). Lipopolysaccharide increases plasma levels of corticotropin-releasing hormone in rats. Neuroendocrinology 93:165–73
  • Grubbs FE. (1969). Procedures for detecting outlying observations in samples. Technometrics 11:1–21
  • Hanley NR, Van de Kar LD. (2003). Serotonin and the neuroendocrine regulation of the hypothalamic–pituitary–adrenal axis in health and disease. Vitam Horm 66:189–255
  • Herman JP, Tasker JG, Ziegler DR, Cullinan WE. (2002). Local circuit regulation of paraventricular nucleus stress integration: glutamate-GABA connections. Pharmacol Biochem Behav 71:457–68
  • Hinz B, Hirschelmann R. (2000). Rapid non-genomic feedback effects of glucocorticoids on CRF-induced ACTH secretion in rats. Pharm Res 17:1273–7
  • Jaferi A, Nowak N, Bhatnagar S. (2003). Negative feedback functions in chronically stressed rats: role of the posterior paraventricular thalamus. Physiol Behav 78:365–73
  • Johnson RF, Johnson AK. (1990). Light/dark cycle modulates food to water intake ratios in rats. Physiol Behav 48:707–11
  • Kaneko M, Hiroshige T. (1978). Site of fast, rate-sensitive feedback inhibition of adrenocorticotropin secretion during stress. Am J Physiol 234:R46–51
  • Keller-Wood M, Dallman MF. (1984). Corticosteroid inhibition of ACTH secretion. Endocr Rev 5:1–24
  • Kitay JI. (1961). Sex differences in adrenal cortical secretion in the rat. Endocrinology 68:818–24
  • Kobayashi N, Machida T, Takahashi T, Takatsu H, Shinkai T, Abe K, Urano S. (2009). Elevation by oxidative stress and aging of hypothalamic-pituitary-adrenal activity in rats and its prevention by vitamin e. J Clin Biochem Nutr 45:207–13
  • Kovacs KJ, Makara GB. (1988). Corticosterone and dexamethasone act at different brain sites to inhibit adrenalectomy-induced adrenocorticotropin hypersecretion. Brain Res 474:205–10
  • Krueger C, Tian L. (2004). A comparison of the general linear mixed model and repeated measures ANOVA using a dataset with multiple missing data points. Biol Res Nurs 6:151–7
  • Lohman RJ, Liu L, Morris M, O'Brien TJ. (2005). Validation of a method for localised microinjection of drugs into thalamic subregions in rats for epilepsy pharmacological studies. J Neurosci Methods 146:191–7
  • Lowry CA, Burke KA, Renner KJ, Moore FL, Orchinik M. (2001). Rapid changes in monoamine levels following administration of corticotropin-releasing factor or corticosterone are localized in the dorsomedial hypothalamus. Horm Behav 39:195–205
  • McEwen BS. (2007). Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev 87:873–904
  • Morin SM, Stotz-Potter EH, DiMicco JA. (2001). Injection of muscimol in dorsomedial hypothalamus and stress-induced Fos expression in paraventricular nucleus. Am J Physiol Regul Integr Comp Physiol 280:R1276–84
  • Ochi M, Tominaga K, Tanaka F, Tanigawa T, Shiba M, Watanabe T, Fujiwara Y, et al. (2008). Effect of chronic stress on gastric emptying and plasma ghrelin levels in rats. Life Sci 82:862–8
  • Park SY, Walker JJ, Johnson NW, Zhao Z, Lightman SL, Spiga F. (2013). Constant light disrupts the circadian rhythm of steroidogenic proteins in the rat adrenal gland. Mol Cell Endocrinol 371:114–23
  • Paxinos G, Watson C. (1998). The rat brain in stereotaxic coordinates, 4th ed. San Diego: Academic Press
  • Petersen RG. (1985). Design and analysis of experiments. New York: Marcel Dekker, Inc
  • Quinn M, Ueno Y, Pae HY, Huang L, Frampton G, Galindo C, Francis H, et al. (2012). Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat. Am J Physiol Gastrointest Liver Physiol 302:G182–93
  • Russell GM, Henley DE, Leendertz J, Douthwaite JA, Wood SA, Stevens A, Woltersdorf WW, et al. (2010). Rapid glucocorticoid receptor-mediated inhibition of hypothalamic-pituitary-adrenal ultradian activity in healthy males. J Neurosci 30:6106–15
  • Samson WK, Taylor MM, Follwell M, Ferguson AV. (2002). Orexin actions in hypothalamic paraventricular nucleus: physiological consequences and cellular correlates. Regul Pept 104:97–103
  • Shekhar A, Katner JS. (1995). Dorsomedial hypothalamic GABA regulates anxiety in the social interaction test. Pharmacol Biochem Behav 50:253–8
  • Shekhar A, Katner JS, Sajdyk TJ, Kohl RR. (2002). Role of norepinephrine in the dorsomedial hypothalamic panic response: an in vivo microdialysis study. Pharmacol Biochem Behav 71:493–500
  • Stotz-Potter EH, Willis LR, DiMicco JA. (1996). Muscimol acts in dorsomedial but not paraventricular hypothalamic nucleus to suppress cardiovascular effects of stress. J Neurosci 16:1173–9
  • Tasker JG, Herman JP. (2011). Mechanisms of rapid glucocorticoid feedback inhibition of the hypothalamic-pituitary-adrenal axis. Stress 14:398–406
  • Thrivikraman KV, Nemeroff CB, Plotsky PM. (2000). Sensitivity to glucocorticoid-mediated fast-feedback regulation of the hypothalamic-pituitary-adrenal axis is dependent upon stressor specific neurocircuitry. Brain Res 870:87–101
  • Tian DR, Li XD, Wang F, Niu DB, He QH, Li YS, Chang JK, et al. (2005). Up-regulation of the expression of cocaine and amphetamine-regulated transcript peptide by electroacupuncture in the arcuate nucleus of diet-induced obese rats. Neurosci Lett 383:17–21
  • Weiser MJ, Osterlund C, Spencer RL. (2011). Inhibitory effects of corticosterone in the hypothalamic paraventricular nucleus (PVN) on stress-induced adrenocorticotrophic hormone secretion and gene expression in the PVN and anterior pituitary. J Neuroendocrinol 23:1231–40
  • Windle RJ, Wood S, Shanks N, Perks P, Conde GL, da Costa AP, Ingram CD, Lightman SL. (1997). Endocrine and behavioural responses to noise stress: comparison of virgin and lactating female rats during non-disrupted maternal activity. J Neuroendocrinol 9:407–14

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