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Review Article

Bone and joint infections by Mucorales, Scedosporium, Fusarium and even rarer fungi

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Pages 158-171 | Received 07 Feb 2014, Accepted 30 Mar 2014, Published online: 09 May 2014

References

  • Alastruey-Izquierdo A, Cuenca-Estrella M, Monzon A, et al. (2008). Antifungal susceptibility profile of clinical Fusarium spp. isolates identified by molecular methods. J Antimicrob Chemother 61:805–9
  • Angelini A, Drago G, Ruggieri P. (2013). Post-tsunami primary Scedosporium apiospermum osteomyelitis of the knee in an immunocompetent patient. Int J Infect Dis 17:e646–9
  • Arockiaraj J, Balaji G, Ashok A, Kokil G. (2012). Amphotericin B cement beads: a good adjunctive treatment for musculoskeletal mucormycosis. Indian J Orthop 46:369–72
  • Auluck A. (2007). Maxillary necrosis by mucormycosis: a case report and literature review. Med Oral Patol Oral Cir Bucal 12:E360–4
  • Beaudreuil S, Buchler M, Al Najjar A, et al. (2003). Acute septic arthritis after kidney transplantation due to Acremonium. Nephrol Dial Transplant 18:850–1
  • Boelaert JR, De Locht M, Van Cutsem J, et al. (1993). Mucormycosis during deferoxamine therapy is a siderophore-mediated infection. In vitro and in vivo animal studies. J Clin Invest 91:1979–86
  • Bourgeois GP, Cafardi JA, Sellheyer K, Andea AA. (2010). Disseminated Fusarium infection originating from paronychia in a neutropenic patient: a case report and review of the literature. Cutis 85:191–4
  • Boutati EI, Anaissie EJ. (1997). Fusarium, a significant emerging pathogen in patients with hematologic malignancy: ten years' experience at a cancer center and implications for management. Blood 90:999–1008
  • Brown OE, Finn R. (1986). Mucormycosis of the mandible. J Oral Maxillofac Surg 44:132–6
  • Brown RB, Lau SK. (2001). Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 3-2001. A 59-year-old diabetic man with unilateral visual loss and oculomotor-nerve palsy. N Engl J Med 344:286–93
  • Buelow DR, Gu Z, Walsh TJ, Hayden RT. (2012). Evaluation of multiplexed PCR and liquid-phase array for identification of respiratory fungal pathogens. Med Mycol 50:775–80
  • Buruma OJ, Craane H, Kunst MW. (1979). Vertebral osteomyelitis and epidural abcess due to mucormycosis, a case report. Clin Neurol Neurosurg 81:39–44
  • Cetrulo CL Jr, Leto Barone AA, Jordan K, et al. (2012). A multi-disciplinary approach to the management of fungal osteomyelitis: current concepts in post-traumatic lower extremity reconstruction: a case report. Microsurgery 32:144–7
  • Chan LL, Singh S, Jones D, et al. (2000). Imaging of mucormycosis skull base osteomyelitis. Am J Neuroradiol 21:828–31
  • Chaudhuri R, Mckeown B, Harrington D, et al. (1992). Mucormycosis osteomyelitis causing avascular necrosis of the cuboid bone: MR imaging findings. Am J Roentgenol 159: 1035–7
  • Chayakulkeeree M, Ghannoum MA, Perfect JR. (2006). Zygomycosis: the re-emerging fungal infection. Eur J Clin Microbiol Infect Dis 25:215–29
  • Chen F, Lu G, Kang Y, et al. (2006). Mucormycosis spondylodiscitis after lumbar disc puncture. Eur Spine J 15:370–6
  • Chowdhary A, Meis JF, Guarro J, et al. (2014). ESCMID/ECMM joint clinical guidelines for the diagnosis and management of systemic phaeohyphomycosis: diseases caused by black fungi. Clin Microbiol Infect 20:47–75
  • Cohen-Abbo A, Edwards KM. (1995). Multifocal osteomyelitis caused by Paecilomyces varioti in a patient with chronic granulomatous disease. Infection 23:55–7
  • Cornely OA. (2008). Aspergillus to Zygomycetes: causes, risk factors, prevention, and treatment of invasive fungal infections. Infection 36:296–313
  • Cornely OA, Arikan-Akdagli S, Dannaoui E, et al. (2014). ESCMID and ECMM joint clinical guidelines for the diagnosis and management of mucormycosis 2013. Clin Microbiol Infect 20:5–26
  • Cornely OA, Vehreschild JJ, Ruping MJ. (2009). Current experience in treating invasive zygomycosis with posaconazole. Clin Microbiol Infect 15:77–81
  • Cortez KJ, Roilides E, Quiroz-Telles F, et al. (2008). Infections caused by Scedosporium spp. Clin Microbiol Rev 21:157–97
  • Dalton PA, Munckhof WJ, Walters DW. (2006). Scedosporium prolificans: an uncommon cause of septic arthritis. ANZ J Surg 76:661–3
  • Dan M, Yossepowitch O, Hendel D, et al. (2006). Phialemonium curvatum arthritis of the knee following intra-articular injection of a corticosteroid. Med Mycol 44:571–4
  • Dannaoui E, Schwarz P, Slany M, et al. (2010). Molecular detection and identification of zygomycetes species from paraffin-embedded tissues in a murine model of disseminated zygomycosis: a collaborative European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Fungal Infection Study Group (EFISG) evaluation. J Clin Microbiol 48:2043–6
  • De Pauw B, Walsh TJ, Donnelly JP, et al. (2008). Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin Infect Dis 46:1813–21
  • Deboni MC, Pozzani VR, Lisboa T, et al. (2006). Mucormycosis in an immunocompetent patient: follow-up of 1 year after treatment. Acta Otolaryngol 126:993–6
  • Eaton ME, Padhye AA, Schwartz DA, Steinberg JP. (1994). Osteomyelitis of the sternum caused by Apophysomyces elegans. J Clin Microbiol 32:2827–8
  • Eckburg PB, Zolopa AR, Montoya JG. (1999). Invasive fungal sinusitis due to Scedosporium apiospermum in a patient with AIDS. Clin Infect Dis 29:212–3
  • Edupuganti S, Rouphael N, Mehta A, et al. (2011). Fusarium falciforme vertebral abscess and osteomyelitis: case report and molecular classification. J Clin Microbiol 49:2350–3
  • Fishman JA, Rubin RH. (1998). Infection in organ-transplant recipients. N Engl J Med 338:1741–51
  • Fogarty C, Regennitter F, Viozzi CF. (2006). Invasive fungal infection of the maxilla following dental extractions in a patient with chronic obstructive pulmonary disease. J Can Dent Assoc 72:149–52
  • Garcia-Vidal C, Cabellos C, Ayats J, et al. (2009). Fungal postoperative spondylodiscitis due to Scedosporium prolificans. Spine J 9:e1–7
  • Gomes MZ, Lewis RE, Kontoyiannis DP. (2011). Mucormycosis caused by unusual mucormycetes, non-Rhizopus, -Mucor, and -Lichtheimia species. Clin Microbiol Rev 24:411–45
  • Gonzalez CE, Rinaldi MG, Sugar AM. (2002). Zygomycosis. Infect Dis Clin North Am 16:895–914, vi
  • Gottesman-Yekutieli T, Shwartz O, Edelman A, et al. (2011). Pseudallescheria boydii infection of a prosthetic hip joint – an uncommon infection in a rare location. Am J Med Sci 342:250–3
  • Guarro J. (2013). Fusariosis, a complex infection caused by a high diversity of fungal species refractory to treatment. Eur J Clin Microbiol Infect Dis 32:1491–500
  • Guarro J, Nucci M, Akiti T, Gene J. (2000). Mixed infection caused by two species of Fusarium in a human immunodeficiency virus-positive patient. J Clin Microbiol 38:3460–2
  • Heath CH, Slavin MA, Sorrell TC, et al. (2009). Population-based surveillance for scedosporiosis in Australia: epidemiology, disease manifestations and emergence of Scedosporium aurantiacum infection. Clin Microbiol Infect 15:689–93
  • Hell M, Neureiter J, Wojna A, et al. (2011). Post-traumatic Pseudallescheria apiosperma osteomyelitis: positive outcome of a young immunocompetent male patient due to surgical intervention and voriconazole therapy. Mycoses 54:43–7
  • Husain S, Munoz P, Forrest G, et al. (2005). Infections due to Scedosporium apiospermum and Scedosporium prolificans in transplant recipients: clinical characteristics and impact of antifungal agent therapy on outcome. Clin Infect Dis 40:89–99
  • Ibrahim AS, Kontoyiannis DP. (2013). Update on mucormycosis pathogenesis. Curr Opin Infect Dis 26:508–15
  • Ibrahim AS, Spellberg B, Walsh TJ, Kontoyiannis DP. (2012). Pathogenesis of mucormycosis. Clin Infect Dis 54:S16–22
  • Islam MN, Cohen DM, Celestina LJ, et al. (2007). Rhinocerebral zygomycosis: an increasingly frequent challenge: update and favorable outcomes in two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:e28–34
  • Jones NF, Shin EK, Eo S, Starzl TE. (2008). Successful salvage of mucormycosis infection of the forearm and osteomyelitis of the ulna. Hand (NY) 3:332–6
  • Jung N, Seifert H, Siewe J, Fatkenheuer G. (2013). Vertebral osteomyelitis. Internist (Berl) 54:945–53
  • Kainer MA, Reagan DR, Nguyen DB, et al. (2012). Fungal infections associated with contaminated methylprednisolone in Tennessee. N Engl J Med 367:2194–203
  • Katragkou A, Walsh TJ, Roilides E. (2013). Why is mucormycosis more difficult to cure than more common mycoses? Clin Microbiol Infect. doi: 10.1111/1469-0691.12466. [Epub ahead of print]
  • Kesson AM, Bellemore MC, O'mara TJ, et al. (2009). Scedosporium prolificans osteomyelitis in an immunocompetent child treated with a novel agent, hexadecylphospocholine (miltefosine), in combination with terbinafine and voriconazole: a case report. Clin Infect Dis 48:1257–61
  • Keynan Y, Sprecher H, Weber G. (2007). Acremonium vertebral osteomyelitis: molecular diagnosis and response to voriconazole. Clin Infect Dis 45:e5–6
  • Kimura M, Maenishi O, Ito H, Ohkusu K. (2010). Unique histological characteristics of Scedosporium that could aid in its identification. Pathol Int 60:131–6
  • Koehler P, Tacke D, Cornely OA. (2014). Aspergillosis of bones and joints – a review from 2002 until today. Mycoses. doi: 10.1111/myc.12165. [Epub ahead of print]
  • Kooijman CM, Kampinga GA, De Hoog GS, et al. (2007). Successful treatment of Scedosporium aurantiacum osteomyelitis in an immunocompetent patient. Surg Infect (Larchmt) 8:605–10
  • Kumashi PR, Safdar A, Chamilos G, et al. (2006). Fungal osteoarticular infections in patients treated at a comprehensive cancer centre: a 10-year retrospective review. Clin Microbiol Infect 12:621–6
  • Lackner M, De Man FH, Eygendaal D, et al. (2011). Severe prosthetic joint infection in an immunocompetent male patient due to a therapy refractory Pseudallescheria apiosperma. Mycoses 54:22–7
  • Levine NB, Kurokawa R, Fichtenbaum CJ, et al. (2002). An immunocompetent patient with primary Scedosporium apiospermum vertebral osteomyelitis. J Spinal Disord Tech 15:425–30
  • Li JY, Yong TY, Grove DI, Coates PT. (2008). Successful control of Scedosporium prolificans septic arthritis and probable osteomyelitis without radical surgery in a long-term renal transplant recipient. Transpl Infect Dis 10:63–5
  • Lionakis MS, Kontoyiannis DP. (2004). Fusarium infections in critically ill patients. Semin Respir Crit Care Med 25:159–69
  • Magnon KC, Jalbert M, Padhye AA. (1993). Osteolytic phaeohyphomycosis caused by Phialemonium obovatum. Arch Pathol Lab Med 117:841–3
  • Mahfouz T, Anaissie E. (2003). Prevention of fungal infections in the immunocompromised host. Curr Opin Investig Drugs 4:974–90
  • Malcolm TR, Chin-Hong PV. (2013). Endemic mycoses in immunocompromised hosts. Curr Infect Dis Rep 15:536–43
  • Marinach-Patrice C, Lethuillier A, Marly A, et al. (2009). Use of mass spectrometry to identify clinical Fusarium isolates. Clin Microbiol Infect 15:634–42
  • Matlani M, Kaur R, Shweta. (2013). A case of scedosporium prolificans osteomyelitis in an immunocompetent child, misdiagnosed as tubercular osteomyelitis. Indian J Dermatol 58:80–1
  • Meis JF, Kullberg BJ, Pruszczynski M, Veth RP. (1994). Severe osteomyelitis due to the zygomycete Apophysomyces elegans. J Clin Microbiol 32:3078–81
  • Mesfin FB, Tobin E, Adamo MA, Dirisio D. (2008). Fungal vertebral osteomyelitis due to Scedosporium apiospermum after near-drowning. J Neurosurg Spine 9:58–61
  • Miceli MH, Lee SA. (2011). Emerging moulds: epidemiological trends and antifungal resistance. Mycoses 54:e666–78
  • Miyakis S, Velegraki A, Delikou S, Parcharidou A, et al. (2006). Invasive Acremonium strictum infection in a bone marrow transplant recipient. Pediatr Infect Dis J 25:273–5
  • Moschovi M, Trimis G, Anastasopoulos J, et al. (2004). Subacute vertebral osteomyelitis in a child with diabetes mellitus associated with Fusarium. Pediatr Int 46:740–2
  • Muhammed M, Coleman JJ, Carneiro HA, Mylonakis E. (2011). The challenge of managing fusariosis. Virulence 2:91–6
  • Mylona E, Samarkos M, Kakalou E, et al. (2009). Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics. Semin Arthritis Rheum 39:10–7
  • Nelson PE, Dignani MC, Anaissie EJ. (1994). Taxonomy, biology, and clinical aspects of Fusarium species. Clin Microbiol Rev 7:479–504
  • Nucci M, Anaissie E. (2002). Cutaneous infection by Fusarium species in healthy and immunocompromised hosts: implications for diagnosis and management. Clin Infect Dis 35:909–20
  • Nucci M, Anaissie E. (2007). Fusarium infections in immunocompromised patients. Clin Microbiol Rev 20:695–704
  • Nucci M, Marr KA, Vehreschild MJ, et al. (2013). Improvement in the outcome of invasive fusariosis in the last decade. Clin Microbiol Infect. doi: 10.1111/1469-0691.12409. [Epub ahead of print]
  • Ochiai N, Shimazaki C, Uchida R, et al. (2003). Disseminated infection due to Scedosporium apiospermum in a patient with acute myelogenous leukemia. Leuk Lymphoma 44:369–72
  • Oswal NP, Gadre PK, Sathe P, Gadre KS. (2012). Mucormycosis of mandible with unfavorable outcome. Case Rep Dent 2012:257940. doi: 10.1155/2012/257940
  • Pagano L, Cornely OA, Busca A, et al. (2013). Combined antifungal approach for the treatment of invasive mucormycosis in patients with hematologic diseases: a report from the SEIFEM and FUNGISCOPE registries. Haematologica 98:e127–30
  • Palestro CJ, Love C, Miller TT. (2006). Infection and musculoskeletal conditions: imaging of musculoskeletal infections. Best Pract Res Clin Rheumatol 20:1197–218
  • Paltauf AP. (1885). Mycosis mucorina. Virchows Arch 102:543–64
  • Panda NK, Singhal SK, Mann SB. (1999). Osteomyelitis of the skull base due to mucormycosis. Indian J Otolaryngol Head Neck Surg 51:47–50
  • Pandey A, Bansal V, Asthana AK, et al. (2011). Maxillary osteomyelitis by mucormycosis: report of four cases. Int J Infect Dis 15:e66–9
  • Parra-Ruiz J, Pena-Monje A, Tomas-Jimenez C, et al. (2008). Septic arthritis due to Absidia corymbifera in a patient with HIV-1 infection. Infection 36:279–81
  • Patterson TF, Mackool BT, Gilman MD, Piris A. (2009). Case records of the Massachusetts General Hospital. Case 22-2009. A 59-year-old man with skin and pulmonary lesions after chemotherapy for leukemia [corrected]. N Engl J Med 361:287–96
  • Pfaller MA, Diekema DJ. (2004). Rare and emerging opportunistic fungal pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigatus. J Clin Microbiol 42:4419–31
  • Phillips P, Forbes JC, Speert DP. (1991). Disseminated infection with Pseudallescheria boydii in a patient with chronic granulomatous disease: response to gamma-interferon plus antifungal chemotherapy. Pediatr Infect Dis J 10:536–9
  • Pierce PF, Wood MB, Roberts GD, et al. (1987). Saksenaea vasiformis osteomyelitis. J Clin Microbiol 25:933–5
  • Reed C, Bryant R, Ibrahim AS, et al. (2008). Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis. Clin Infect Dis 47:364–71
  • Ribes JA, Vanover-Sams CL, Baker DJ. (2000). Zygomycetes in human disease. Clin Microbiol Rev 13:236–301
  • Roden MM, Zaoutis TE, Buchanan WL, et al. (2005). Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 41:634–53
  • Rogasi PG, Zanazzi M, Nocentini J, et al. (2007). Disseminated Scedosporium apiospermum infection in renal transplant recipient: long-term successful treatment with voriconazole: a case report. Transplant Proc 39:2033–5
  • Roilides E, Sigler L, Bibashi E, et al. (1999). Disseminated infection due to Chrysosporium zonatum in a patient with chronic granulomatous disease and review of non-Aspergillus fungal infections in patients with this disease. J Clin Microbiol 37:18–25
  • Ruping MJ, Heinz WJ, Kindo AJ, et al. (2010). Forty-one recent cases of invasive zygomycosis from a global clinical registry. J Antimicrob Chemother 65:296–302
  • Shaw CJ, Thomason AJ, Spencer JD. (1994). Fungal osteomyelitis of the foot. A report of an unusual case. J Bone Joint Surg Br 76:137–9
  • Sierra-Hoffman M, Paltiyevich-Gibson S, Carpenter JL, Hurley DL. (2005). Fusarium osteomyelitis: case report and review of the literature. Scand J Infect Dis 37:237–40
  • Spellberg B, Ibrahim A, Roilides E, et al. (2012). Combination therapy for mucormycosis: why, what, and how?. Clin Infect Dis 54:S73–8
  • Steinbach WJ, Perfect JR. (2003). Scedosporium species infections and treatments. J Chemother 15:16–27
  • Steinbach WJ, Schell WA, Miller JL, Perfect JR. (2003). Scedosporium prolificans osteomyelitis in an immunocompetent child treated with voriconazole and caspofungin, as well as locally applied polyhexamethylene biguanide. J Clin Microbiol 41:3981–5
  • Stripeli F, Pasparakis D, Velegraki A, et al. (2009). Scedosporium apiospermum skeletal infection in an immunocompetent child. Med Mycol 47:441–4
  • Studahl M, Backteman T, Stalhammar F, et al. (2003). Bone and joint infection after traumatic implantation of Scedosporium prolificans treated with voriconazole and surgery. Acta Paediatr 92:980–2
  • Sydnor MK, Kaushik S, Knight TE Jr, et al. (2003). Mycotic osteomyelitis due to Scedosporium apiospermum: MR imaging-pathologic correlation. Skeletal Radiol 32:656–60
  • Terada M, Fujita J, Watanabe S, et al. (2011). Olecranon bursa with Fusarium solani infection in an otherwise healthy patient. Mycoses 54:e853–5
  • Torres HA, Raad II, Kontoyiannis DP. (2003). Infections caused by Fusarium species. J Chemother 15:28–35
  • Tortorano AM, Richardson M, Roilides E, et al. (2014). ESCMID and ECMM joint guidelines on diagnosis and management of hyalohyphomycosis: Fusarium spp., Scedosporium spp. and others. Clin Microbiol Infect 20:27–46
  • Troke P, Aguirrebengoa K, Arteaga C, et al. (2008). Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients. Antimicrob Agents Chemother 52:1743–50
  • Vashi N, Avedian R, Brown J, Arai S. (2012). Successful surgical and medical treatment of rhizopus osteomyelitis following hematopoietic cell transplantation. Orthopedics 35:e1556–61
  • Vasoo S, Yeo SB, Lim PL, et al. (2008). Efficacy of voriconazole for Scedosporium apiospermum skull base osteomyelitis: case report and literature review. Int J Antimicrob Agents 31:184–5
  • Vehreschild JJ, Birtel A, Vehreschild MJ, et al. (2013). Mucormycosis treated with posaconazole: review of 96 case reports. Crit Rev Microbiol 39:310–24
  • Walsh TJ, Gamaletsou MN. (2013). Treatment of fungal disease in the setting of neutropenia. Hematology Am Soc Hematol Educ Program 2013:423–7
  • Walsh TJ, Groll A, Hiemenz J, et al. (2004). Infections due to emerging and uncommon medically important fungal pathogens. Clin Microbiol Infect 10:48–66
  • Wilkins RM, Hahn DB, Blum R. (2009). Bread mold osteomyelitis in the femur. Orthopedics 32:362
  • Wu CY, Chen GS, Lan CC. (2009). Onychomycosis caused by Fusarium solani in a woman with diabetes. Clin Exp Dermatol 34:e772–4
  • Zimmerli W. (2010). Clinical practice: Vertebral osteomyelitis. N Engl J Med 362:1022–9

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