10
Views
10
CrossRef citations to date
0
Altmetric
Original Article

Genomic organization of the human homologue of the rat pancreatic elastase I gene

, , , , , & show all
Pages 303-312 | Received 13 Aug 1991, Published online: 11 Jul 2009

References

  • Benton W. D., Davis R. W. Screening γgt recombinant clones by hybridization to single plaques in situ. Science 1977; 196: 180–182
  • Breathnach R., Benoist C., O'Hare K., Cannon F., Chambon P. Ovalbumin gene: Evidence for a leader sequence in mRNA and DNA sequences at the exonintron boundaries. Proc. Natl. Acad. Sci. USA 1978; 75: 4853–4857
  • Geokas M. C., Rinderknecht H., Swanson V., Haverback B. J. The role of elastase in acute hemorrhagic pancreatitis in man. Lab. Invest. 1968; 19: 235–239
  • Geokas M. C., Brodrick J. W., Johnson J. H., Largman C. Pancreatic elastase in human serum: Determination by radioimmunoassay. J. Biol. Chem. 1977; 252: 61–67
  • Cross-Bellard M., Oudet P., Chambon P. Isolation of high-molecular-weight DNA from mammalian cells. Eur. J. Biochem. 1973; 36: 32–38
  • Hartley B. S., Shotton D. M. Pancreatic elastase. The Enzymes3rd ed., P. D. Boyerl. Academic Press, New York 1971; Vol. 3: 323–373
  • Hornebeck W., Robert L. Elastase-like enzymes in aortas and human breast carcinomas: Quantitative variations with age and pathology. Elastin and Elastic Tissue, L. Sandberg, W. R. Gray, C. Franyblau. Plenum Press, New York 1977; 145–164
  • Jurka J. Novel families of interspersed repetitive elements from the human genome. Nucleic Acids Res. 1990; 18: 137–141
  • Kaplan P. D., Kuhn C., Piecre J. A. The induction of emphysema with elastase: The evolution of the lesion and the influence of serum. J. Lab. Clin. Med. 1973; 82: 349–356
  • Kawashima I., Tani T., Shimoda K., Takiguchi Y. Characterization of pancreatic elastase II cDNAs: Two elastase II mRNAs are expressed in human pancreas. DNA 1987; 6: 163–172
  • Kawashima I., Mita-Honjo K., Takiguchi Y. Characterization of the primate-specific repetitive DNA element MERl. DNA Sequence 1992; 3: 313–318
  • Kruse F., Komro C. T., Michnoff C. H., MacDonald R. J. The cell-specific elastase I enhancer comprises two domains. Mol. Cell. Biol. 1988; 8: 893–902
  • Largman C. Isolation and characterization of rat pancreatic elastase. Biochemistry 1983; 22: 3763–3770
  • Largman C., Brodrick J. W., Geokas M. C. Purification and characterization of two human pancreatic elastases. Biochemistry 1976; 15: 2491–2500
  • Largman C., Brodrick J. W., Geokas M. C., Johnson J. H., Fassett M. Demonstration of a pancreatic proelastase 2–α1-protease inhibitor complex in normal human plasma. Am. J, Physiol 1980; 238: G177–GlE2, Gastrointest. Liver Physiol. 1
  • MacDonald R. J., Swift G. H., Quinto C., Swain W., Pictet R. L., Nikovits W., Rutter W. J. Primary structure of two distinct rat pancreatic preproelastases determined by sequence analysis of the complete cloned messenger ribo-nucleic acid sequences. Biochemistry 1982; 21: 1453–1463
  • Maniatis T., Fritsch E. F., Sambrook J. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, New York 1982
  • Ornitz D. M., Palmiter R. D., Hammer R. E., Brinster R. L., Swift G. H., MacDonald R. J. Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice. Nature 1985; 313: 600–602
  • Saiki R. K., Gelfand D. H., Stoffel S., Scharf S. J., Higuchi R., Horn G. T., Mullis K. B., Erlich H. A. Primerdirected enzymatic amplification of DNA with a thermostable DNA polymerase. Science 1988; 239: 487–491
  • Sanger F., Nicklen S., Coulson A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 1977; 74: 5463–5467
  • Shapiro M. B., Senapathy P. RNA splice junctions of different classes of eukaryotes: Sequence statistics and functional implications in gene expression. Nucleic Acids Res. 1987; 15: 7155–7174
  • Shen W.-F., Fletcher T. S., Largman C. Primary structure of human pancreatic protease E determined by sequence analysis of the cloned mRNA. Biochemistry 1987; 26: 3447–3452
  • Shi Y., Son H. J., Shahan K., Rodriguez M., Costantini F., Derman E. Silent genes in the mouse major urinary protein gene family. Proc. Natl. Acad. Sci. USA 1989; 86: 4584–4588
  • Shirasu Y., Yoshida H., Mikayama T., Matsuki S., Tanaka J., Ikenaga H. Isolation and expression in Escherichia coli of a cDNA clone encoding porcine pancreatic elastase. J. Biochem. 1986; 99: 1707–1712
  • Swift C. H., Craik C. S., Stary S. J., Quinto C., Lahaie R. G., Rutter W. J., MacDonald R. J. Structure of the two related elastase genes expressed in the rat pancreas. J. Biol. Chem. 1984; 259: 14271–14278
  • Tani T., Kawashima I., Furukawa H., Ohmine T., Takiguchi Y. Characterization of a silent gene for human pancreatic elastase I: Structure of the 5′-flanking region. J. Biochem. 1987; 101: 591–599
  • Tani T., Ohsumi J., Mita K., Takiguchi Y. Identification of a novel class of elastase isozyme, human pancreatic elastase III, by cDNA and genomic gene cloning. J. Biol. Chem. 1988; 263: 1231–1239
  • von Heijne C. Signal sequences: The limits of variation. J. Mol. Biol. 1985; 184: 99–105

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.