10
Views
4
CrossRef citations to date
0
Altmetric
Original Article

Intravenous Bolus Topotecan in Patients with Myelodysplastic Syndrome

, , , , , , & show all
Pages 963-968 | Published online: 01 Jul 2009

References

  • Raza A., Gezer S., Mundel S., Gao X. Z., Alvi S., Borok R, Rifkin S., Iftikhar A., Shetty V., Parcharidou A. Apoptosis in bone marrow samples involving strormal and hematopoietic cells in 50 patients with myelodysplastic syndromes. Blood 1995; 86: 268–276
  • Greenberg P., Cox C., LeBeau M., Fenaux P., Morel P., Sanz G., Sanz M., Vallespi T., Hamblin T., Oscier D., Ohyashiki K., Toyama K., Aul C., Mufti G., Bennett J. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997; 89: 2079–2088
  • Kantarjian H. M., Beran M., Ellis A., Zwelling L., O'Brien S., Cazenave L., Koller C., Rios M. B., Plunkett W., Keating M. J. Phase I study of topotecan, a new topoisomerase I inhibitor, in patients with refractory or relapsed acute leukemia. Blood 1993; 81: 1146–1151
  • Rowinsky E. K., Adjei A., Donehower R. C., Gore S. D., Jones R. J., Burke P. J., Cheng Y. C., Grochow L. B., Kaufmann S. H. Phase I and pharmacodynamic study of the topoisomerase I-inhibitor topotecan in patients with refractory acute leukemia. Journal of Clinical Oncology 1994; 12: 2193–2203
  • Seiter K., Feldman E. J., Halicka H. D., Traganos F., Darzynkiewicz Z., Lake D., Ahmed T. Phase I clinical and laboratory evaluation of topotecan and cytarabine in patients with acute leukemia. Journal of Clinical Oncology 1997; 15: 44–51
  • Lynch T. J., Jr., Kalish L., Strauss G., Elias A., Skarin A., Shulman L. N., Posner M., Frei E. 3rd Phase II study of topotecan in metastatic non-small-cell lung cancer. Journal of Clinical Oncology 1994; 12: 347–352
  • Creemers G. J., Bolis G., Gore M., Scarfone G., Lacave A. J., Guastalla J. P., Despax R., Favalli G., Kreenberg R., Van Belle S., Hudson I., Verweij J., Bokkel Ten, Huinink W. W. Topotecan, an active drug in the second-line treatment of epithelial ovarian cancer: results of a large European phase n study. Journal of Clinical Oncology 1996; 14: 3056–3061
  • Beran M., Kantarjian H., O'Brien S., Koller C., al-Bitar M., Arbuck S., Pierce S., Moore M., Abbruzzese J. L., Andreeff M., Keating M., Estey E. Topotecan, a topoisomerase I inhibitor, is active in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood 1996; 88: 2473–2479
  • Beran M., Estey E., O'Brien S., Cortes J., Koller C. A., Giles R, Kornblau S., Andreeff M., Vey N., Pierce S. R., Hayes K., Wong G.C., Keating M., Kantarjian H. Topotecan and cytarabine is an active combination regimen in myelodysplastic syndromes and chronic myelomonocytic leukemia. Journal of Clinical Oncology 1999; 17: 2819–2830
  • National Cancer Institute Common Toxicity Criteria, Version 2.0, April 30, 1999
  • Rowinsky E. R., Kaufmann S. H., Baker S. D., Miller C. B., Sartorius S. E., Bowling M. K., Chen T.-L., Donehower R. C., Gore S. D. A phase I and pharmacological study of topotecan infused over 30 minutes for five days in patients with refractory acute leukemia. Clinical Cancer Research 1996; 2: 1921–1930

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.