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Original Article

Correlation Between Decreased Apoptosis and Multidrug Resistance (MDR) in Murine Leukemic T Cell Lines

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Pages 775-787 | Accepted 24 Jan 2001, Published online: 01 Jul 2009

References

  • Chabner B. A., Myers C. E. Clinical pharmacology of cancer chemotherapy. In Cancer: Principles and practice of oncology, VTJ de Vita, S Hellmann, SA Rosenberg. Lippincott, Philadelphia 1989; 349–378
  • Buzaid A. C., Cadman E. Pharmacology of antineoplastic agents and mechanisms of multidrug resistance. In Hematology: basic principles and practice, R Hoffinan, EJJ Benz, SJ Shattil, HJ Furie and Cohen. Churchill Livingstone, New York 1991; 669–683
  • Helmberg A., Auphan N., Caelles C., Karin M. Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor. The EMBO J 1995; 14: 452–460
  • Liu P., Oken M., Van Ness B. Interferon-a protects myeloma cell lines from dexamethasone-induced apoptosis. Leukemia 1999; 13: 473–480
  • Ueda K., Cornwell M. M., Gottesman M. M., Pastan I., Roninson I. B., Ling V., Riordan J. R. The mdr1 gene, responsible for multi-drug resistance, codes for P-glycoprotein. Biochem Biophys Res Commun 1986; 141: 956–962
  • Fojo A. T., Ueda K., Slamon D. J., Poplack D. G., Gottesman M. M., Pastan I. Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 1987; 84: 265–269
  • Johnstone R. W., Cretney E., Smyth M. J. P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death. Blood 1999; 93: 1075–1085
  • Lehne G., De Angelis P., Boer M., Rugstad H. E. Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents. Leukemia 1999; 13: 768–778
  • Bertino J. R., Lin J., Pizzorno G., Li W. W., Chang Y. M. The basis for intrinsic drug resistance or sensitivity to methotrexate. Adv Enzyme Regul 1989; 29: 277–285
  • Simon S. M., Schindler M. Cell biological mechanisms of multidrug resistance in tumors. Proc Natl Acad Sci USA 1994; 91: 3497–3504
  • Huschtscha L. I., Bartier W. A., Ross C. E., Tattersall M. H. Characteristics of cancer cell death after exposure to cytotoxic drugs in vitro. Br J Cancer 1996; 73: 54–60
  • Kondo S., Kondo Y., Hara H., Kaakaji R., Peterson J. W., Morimura T., Takeuchi J., Barnett G. H. mdm2 gene mediates the expression of mdr1 gene and P-glycoprotein in a human glioblastoma cell line. Br J Cancer 1996; 74: 1263–1268
  • Barry M., Behnke C. A., Eastman A. Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem Pharmacol 1990; 40: 2353–2362
  • Hickman J. A., Potten C. S., Merrit A. J., Fisher T. C. Apoptosis and cancer chemotherapy. Philos Trans R Soc Lon B Biol Sci 1994; 345: 319–325
  • Blagosklonny M. V. Drug-resistance enables selective killing of resistant leukemia cells: exploiting of drug resistance instead of reversal. Leukemia 1999; 13: 2031–2035
  • Kaufinan D., Chabner B. A. Clinical Strategies for Cancer Treatment: The role of drugs. In Cancer chemotherapy and biotherapy: Principles and practice, BA Chabner, DL Longo. Lippincott-Raven Publishers, Philadelphia 1996; 01–16
  • Efferth T., Fabry U., Osieka R. Apoptosis and resistance to daunorubicin in human leukemic cells. Leukemia 1997; 11: 1180–1186
  • Kerr J. F.R., Willie A. H., Currie A. R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239–257
  • Vaux D. L. Toward an understanding of the molecular mechanisms of physiological cell death. Proc Natl Acad Sci USA 1993; 90: 786–789
  • Wood A. C., Elvin P., Hickman J. A. Induction of apoptosis by anti-cancer drugs with disparate modes of action: kinetics of cell death and changes in c-myc expression. Br J Cancer 1995; 71: 937–941
  • Li X., Gong J., Feldman E., Seiter K., Traganos F., Darzynkiewicz Z. Apoptotic cell death during treatment of leukemias. Leuk Lymphoma 1994; 13: 65–70, Suppl. 1
  • Lopes E. C., Scolnik M., Alvarez E., Hajos S. E. Cytotoxic effect of cyclosporin-A and PSC 833 in vincristine and doxorubicin-selected multidrug resistant murine leukemic cells. Leukemia Res 2001; 25: 85–93
  • Alvarez E., Mongini C., Waldner C. I., Fernández T., Naor D., Hajos S. The interrelationships between spontaneous murine T cell leukaemia LB and the immune system: LB is a non-immunogenic tumor in its syngeneic host. Journal of Experimental and Clinical Cancer Res 1989; 8: 181–192
  • Lugasi H., Hajos S. E., Murphy J. R., Strom T. B., Nichols J., Peñarroja C., Naor D. Murine spontaneous T-cell leukemia constitutively expressing IL-2 receptor. A model for human T-cell malignancies expressing IL-2R. Int J Cancer 1990; 45: 163–167
  • Flórez J. Farmacología Humana. Masson S.A, Barcelona 1997; 13–16
  • Mishell B. B., Shiigi S. M., Henry C., Chan E. L., North J., Gallily R., Slomich M., Miller K., Marbrook J., Parks D. Good AH Preparation of mouse cell suspensions. In Selected Methods in Cellular Immunology, BB Mishell, SM Shiigi, Freeman WH, New York 1980; 21–22
  • Migita K., Eguchi K., Kawabe Y., Tsukuba T., Mizokami A., Nagataki S. FK506 augments activation-induced programmed cell death of lymphocytes in vivo. J Clin Invest 1995; 96: 727–732
  • Slapak C. A., Daniel J. C., Levy S. B. Sequential emergence of distinct resistance phenotypes in murine erythroleukemia cells under adriamycin selection: decreased anthracycline uptake precedes increased P-glycoprotein expression. Cancer Res 1990; 50: 7895–7901
  • Huang Y., Ibrado A. M., Reed J. C., Bullock G., Ray S., Tang C., Bhalla K. Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells. Leukemia 1997; 11: 253–257
  • Fisher D. E. Apoptosis in cancer therapy: crossing the threshold. Cell 1994; 78: 539–542
  • Friesen C., Fulda S., Debatin K. M. Cytotoxic drugs and the CD95 pathway. Leukemia 1999; 13: 1854–1858
  • Pastan I., Gottesman M. M., Ueda K. Eretrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. Proc Natl Acad Sci USA 1988; 85: 4486–4490
  • Gruol D. J., Vo Q. D., Zee M. C. Profound differences in the transport of steroids by two mouse P-glycoproteins. Biochem Pharmacol 1999; 58: 1191–1199
  • Schwartzman R. A., Cidlowski J. A. Glucocorticoid-induced apoptosis of lymphoid cells (review). Intl Arch Aller Immunol 1994; 105: 347–354
  • Wood A. C., Waters C. M., Garner A., Hickman J. A. Changes in c-myc expression and the kinetics of dexamethasone-induced programmed cell death (apoptosis) in human lymphoid leukaemia cells. Br J Cancer 1994; 69: 633–669
  • Randas J., Harmon J. M. Glucocorticoid-induced apoptosis and regulation of NF-κB activity in human leukemic T cells. Endocrinology 1998; 139: 3813–3821
  • Guizani L., Perrinwolff M., Breard J., Binetruy B., Bertoglio J. Mechanisms in interleukin-2 protection against glucocorticoid-induced apoptosis — regulation of AP-1 and glucocorticoid receptor transcriptional activities. J Int Cytok Res 1996; 16: 601–609
  • Waldner C. I., Mongini C., Alvarez E., Sánchez L. M., Gravisaco M. J., Hajos S. E. Interleukin 2 exerts autocrine stimulation on murine T-cell leukemia growth. Br J Cancer 1997; 75: 946–950
  • Smets L. A., Van den Berg J., Acton D., Top B., Van Rooij H., Janssen M. V. Bc1–2 expression and mitochondrial activity in leukemic cells with different sensitivity to glucocorticoid-induced apoptosis. Blood 1994; 84: 1613–1619

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