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Original Articles: Clinical

Treatment of t(11;18)-positive gastric mucosa-associated lymphoid tissue lymphoma with rituximab and chlorambucil: clinical, histological, and molecular follow-up

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Pages 284-290 | Received 25 Aug 2009, Accepted 20 Oct 2009, Published online: 28 Dec 2009

References

  • Ye H, Liu H, Attygalle A, et al Variable frequencies of t(11;18)(q21;q21) in MALT lymphomas of different sites: significant association with CagA strains of H. pylori in gastric MALT lymphoma. Blood 2003;102:1012–1018.
  • Streubel B, Simonitsch-Klupp I, Müllauer L, et al Variable frequencies of MALT lymphoma-associated genetic aberrations in MALT lymphomas of different sites. Leukemia 2004;18:1722–1726.
  • Inagaki H, Nakamura T, Li C, et al Gastric MALT lymphomas are divided into three groups based on responsiveness to Helicobacter Pylori eradication and detection of API2-MALT1 fusion. Am J Surg Pathol 2004;28:1560–1567.
  • Dierlamm J, Baens M, Wlodarska I, et al The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa- associated lymphoid tissue lymphomas. Blood 1999;93:3601–3609.
  • Liu H, Ye H, Ruskone-Fourmestraux A, et al T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication. Gastroenterology 2002;122:1286–1294.
  • Ferrucci PF, Zucca E. Primary gastric lymphoma pathogenesis and treatment: what has changed over the past 10 years? Br J Haematol 2007;136:521–538.
  • Tsang RW, Gospodarowicz MK, Pintilie M, et al Localized mucosa-associated lymphoid tissue lymphoma treated with radiation therapy has excellent clinical outcome. J Clin Oncol 2003;21:4157–4164.
  • Hammel P, Haioun C, Chaumette MT, et al Efficacy of single-agent chemotherapy in low-grade B-cell mucosa-associated lymphoid tissue lymphoma with prominent gastric expression. J Clin Oncol 1995;13:2524–2529.
  • Lévy M, Copie-Bergman C, Traulle C, et al Conservative treatment of primary gastric low grade B-cell lymphoma of mucosa-associated lymphoid tissue: predictive factors of response and outcome. Am J Gastroenterol 2002;97:292–297.
  • Lévy M, Copie-Bergman C, Gameiro C, et al Prognostic value of translocation t(11;18) in tumoural response of low-grade gastric lymphoma of mucosa-associated lymphoid tissue type to oral chemotherapy. J Clin Oncol 2005;23:5061–5066.
  • Raderer M, Jager G, Brugger S, et al Rituximab for treatment of advanced extranodal marginal zone B cell lymphoma of the mucosa-associated lymphoid tissue lymphoma. Oncology 2003;65:306–310.
  • Conconi A, Martinelli G, Thieblemont C, et al Clinical activity of rituximab in extranodal marginal zone B-cell lymphoma of MALT type. Blood 2003;102:2741–2745.
  • Martinelli G, Laszlo D, Ferreri AJ, et al Clinical activity of rituximab in gastric marginal zone non Hodgkin's lymphoma resistant to or non eligible for anti-Helicobacter pylori therapy. J Clin Oncol 2005;23:1979–1983.
  • Musshoff K. Klinische stadieneinteilung der nicht-Hodgkin lymphome. Strahlentherapie 1977;153:218–221.
  • Lévy M, Hammel P, Lamarque D, et al Endoscopic ultrasonography for the initial staging and follow-up in patients with low-grade gastric lymphoma of mucosa-associated lymphoid tissue treated medically. Gastrointest Endosc 1997;46:328–333.
  • Martinelli G, Laszlo D, Bertolini F, et al Chlorambucil in combination with induction and maintenance rituximab is feasible and active in indolent non-Hodgkin's lymphoma. Br J Haematol 2003;123:271–277.
  • Isaacson PG, Wright DH. Malignant lymphoma of mucosa-associated lymphoid tissue. A distinctive type of B-cell lymphoma. Cancer 1983;52:1410–1416.
  • Tankovic J, Chaumette-Planckaert MT, Deforges L et al Routine use of real-time PCR for detection of Helicobcater pylori and of clarithromycine resistance mutations. Gastroenterol Clin Biol 2007;31:792–795.
  • Copie-Bergman C, Gaulard P, Lavergne-Slove A, et al Proposal for a new histological grading system for post-treatment evaluation of gastric MALT lymphoma. Gut 2003;52:1656.
  • Zompi S, Couderc LJ, Cadranel J, et al Clonality analysis of alveolar B lymphocytes contributes to the diagnostic strategy in clinical suspicion of pulmonary lymphoma. Blood 2004;103:3208–3215.
  • Streubel B, Ye H, Du MQ, et al Translocation t(11 18)(q21 q21) is not predictive of response to chemotherapy with 2CdA in patients with gastric MALT lymphoma. Oncology 2004;66:476–480.
  • Zinzani PL, Stefoni V, Musuraca G, et al Fludarabine-containing chemotherapy as frontline treatment of non gastrointestinal mucosa-associated lymphoid tissue lymphoma. Cancer 2004;100:2190–2194.
  • Bertoni F, Conconi A, Capella C, et al Molecular follow-up in gastric mucosa-associated lymphoid tissue lymphomas: early analysis of the LY03 cooperative trial. Blood 2002;99:2541–2544.
  • Thiede C, Wündisch T, Alpen B, et al Long-term persistence of monoclonal B cells after cure of Helicobacter pylori infection and complete histologic remission in gastric mucosa-associated lymphoid tissue B-cell lymphoma. J Clin Oncol 2001;19:1600–1609.
  • de Mascarel A, Ruskone-Fourmestraux A, Lavergne-Slove A, Megraud F, Dubus P, Merlio JP Clinical, histological and molecular follow-up of 60 patients with gastric marginal zone lymphoma of mucosa-associated lymphoid tissue. Virchows Arch 2005;446:219–224.
  • Wündisch T, Thiede C, Morgner A, et al Long-term follow-up of gastric MALT lymphoma after Helicobacter pylori eradication. J Clin Oncol 2005;23:8018–8024.
  • Montalban C, Santon A, Redondo C, et al Long-term persistence of molecular disease after histological remission in low-grade gastric MALT lymphoma treated with H. pylori eradication. Lack of association with translocation t(11;18): a 10-year updated follow-up of a prospective study. Ann Oncol 2005;16:1539–1544.
  • Salar A, Bellosillo B, Serrano S, Besses C. Persistent residual disease in t(11;18)(q21 q21) positive gastric mucosa-associated lymphoid tissue lymphoma treated with chemotherapy or rituximab. J Clin Oncol 2005;23:7361–7362.
  • Santón A, García-Cosio M, Bellosillo B, et al Persistent monoclonality after histological remission in gastric mucosa-associated lymphoid tissue lymphoma treated with chemotherapy and/or surgery: influence of t(11;18)(q21;q21). Leuk Lymphoma 2008;49:1516–1522.
  • Raderer M, Streubel B, Woehrer S, et al High relapse rate in patients with MALT lymphoma warrants lifelong follow-up. Clin Cancer Res 2005;11:3349–3352.
  • Copie-Bergman C, Locher C, Lévy M, et al Metachronous gastric MALT lymphoma and early gastric cancer: is residual lymphoma a risk factor for the development of gastric carcinoma? Ann Oncol 2005;16:1232–1236.

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