103
Views
0
CrossRef citations to date
0
Altmetric
Letters to the Editor

Therapy-related myeloid neoplasm in a patient with TP53 mutation: a dilemma in allogeneic stem cell transplant

, , , , , & show all
Pages 1144-1147 | Received 22 Jan 2010, Accepted 22 Mar 2010, Published online: 05 May 2010

References

  • Li FP, Fraumeni JF Jr, Mulvihill JJ, et al A cancer family syndrome in twenty-four kindreds. Cancer Res 1988;48:5358–5362.
  • Olivier M, Goldgar DE, Sodha N, et al Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype. Cancer Res 2003;63:6643–6650.
  • Larson RA. Therapy-related myeloid neoplasms. Haematologica 2009;94:454–459.
  • Kroger N, Brand R, van Biezen A, et al Risk factors for therapy-related myelodysplastic syndrome and acute myeloid leukemia treated with allogeneic stem cell transplantation. Haematologica 2009;94:542–549.
  • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323–331.
  • Christiansen DH, Andersen MK, Pedersen-Bjergaard J. Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis. J Clin Oncol 2001;19:1405–1413.
  • Pedersen-Bjergaard J, Andersen MK, Andersen MT, Christiansen DH. Genetics of therapy-related myelodysplasia and acute myeloid leukemia. Leukemia 2008;22:240–248.
  • Gonzalez KD, Buzin CH, Noltner KA, et al High frequency of de novo mutations in Li-Fraumeni syndrome. J Med Genet 2009;46:689–693.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.