References
- Schoch C, Schnittger S, Klaus M, Kern W, Hiddemann W, Haferlach T. AML with 11q23/MLL abnormalities as defined by the WHO classification: incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in an unselected series of 1897 cytogenetically analyzed AML cases. Blood 2003;102:2395–2402.
- DiMartino JF, Cleary ML. MLL rearrangements in haematological malignancies: lessons from clinical and biological studies. Br J Haematol 1999;106:614–626.
- Secker-Walker LM, Moorman AV, Bain BJ, Mehta AB. Secondary acute leukemia and myelodysplastic syndrome with 11q23 abnormalities. EU Concerted Action 11q23 Workshop. Leukemia 1998;12:840–844.
- Shaffer LG, Tommerup N, editors. ISCN 2005: An International System for Human Cytogenetic Nomenclature (2005). Basel: Karger; 2005.
- Morel F, Le Bris MJ, Douet-Guilbert N, et al Insertion of chromosome 11 in chromosome 4 resulting in a 5′MLL-3′AF4 fusion gene in a case of adult acute lymphoblastic leukemia. Cancer Genet Cytogenet 2003;145:74–77.
- Meyer C, Schneider B, Reichel M, et al Diagnostic tool for the identification of MLL rearrangements including unknown partner genes. Proc Natl Acad Sci USA 2005;102:449–454.
- Prasad R, Gu Y, Alder H, et al Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation. Cancer Res 1993;53:5624–5628.
- Saito S, Matsushima M, Shirahama S, et al Complete genomic structure DNA polymorphisms, and alternative splicing of the human AF-6 gene. DNA Res 1998;5:115–120.
- Kuriyama M, Harada N, Kuroda S, et al Identification of AF-6 and canoe as putative targets for Ras. J Biol Chem 1996;271:607–610.
- Lue RA, Marfatia SM, Branton D, Chishti AH. Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1. Proc Natl Acad Sci USA 1994;91:9818–9822.
- Joh T, Yamamoto K, Kagami Y, et al Chimeric MLL products with a Ras binding cytoplasmic protein AF6 involved in t(6;11)(q27;q23) leukemia localize in the nucleus. Oncogene 1997;15:1681–1687.
- Kobayashi H, Espinosa R III, Thirman MJ, et al Do terminal deletions of 11q23 exist? Identification of undetected translocations with fluorescence in situ hybridization. Genes Chromosomes Cancer 1993;7:204–208.
- Barber KE, Ford AM, Harris RL, Harrison CJ, Moorman AV. MLL translocations with concurrent 3′ deletions: interpretation of FISH results. Genes Chromosomes Cancer 2004;41:266–271.
- Kolomietz E, Al-Maghrabi J, Brennan S, et al Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis. Blood 2001;97:3581–3588.
- Morel F, Ka C, Le Bris MJ, et al Deletion of the 5′abl region in Philadelphia chromosome-positive chronic myeloid leukemia. Leukemia 2003;17:473–474.
- Konig M, Reichel M, Marschalek R, Haas OA, Strehl S. A highly specific and sensitive fluorescence in situ hybridization assay for the detection of t(4;11)(q21;q23) and concurrent submicroscopic deletions in acute leukaemias. Br J Haematol 2002;116:758–764.
- Martineau M, Berger R, Lillington DM, Moorman AV, Secker-Walker LM. The t(6;11)(q27;q23) translocation in acute leukemia: a laboratory and clinical study of 30 cases. EU Concerted Action 11q23 Workshop participants. Leukemia 1998;12:788–791.
- So CW, Karsunky H, Passegue E, Cozzio A, Weissman IL, Cleary ML. MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice. Cancer Cell 2003;3:161–171.
- Cozzio A, Passegue E, Ayton PM, Karsunky H, Cleary ML, Weissman IL. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev 2003;17:3029–3035.
- Krivtsov AV, Twomey D, Feng Z, et al Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 2006;442:818–822.
- Somervaille TC, Cleary ML. Identification and characterization of leukemia stem cells in murine MLL- AF9 acute myeloid leukemia. Cancer Cell 2006;10:257–268.
- Meyer C, Kowarz E, Hofmann J, et al New insights to the MLL recombinome of acute leukemias. Leukemia 2009;23:1490–1499.