345
Views
0
CrossRef citations to date
0
Altmetric
Commentary

Multidrug resistance: overcoming the good, the bad, and the ugly

Pages 1771-1772 | Published online: 17 Sep 2010

References

  • Drain S, Catherwood MA, Alexander HD. Multidrug resistance in the chronic lymphoproliferative disorders. Leuk Lymphoma 2010;51:1793–1804.
  • Juliano RL, Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 1976;455:152–162.
  • Chen CJ, Chin JE, Ueda K, et al Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 1986;47:381–389.
  • Mellor HR, Callaghan R. Resistance to chemotherapy in cancer: a complex and integrated cellular response. Pharmacology 2008;81:275–300.
  • Gottesman MM, Hrycyna CA, Schoenlein PV, Germann UA, Pastan I. Genetic analysis of the multidrug transporter. Annu Rev Genet 1995;29:607–649.
  • Thomas J, Wang L, Clark RE, Pirmohamed M. Active transport of imatinib into and out of cells: implications for drug resistance. Blood 2004;104:3739–3745.
  • Pastan I, Gottesman MM. Multidrug resistance. Annu Rev Med 1991;42:277–286.
  • Steiner H, Polliack A, Kimchi-Sarfaty C, Libster D, Fibach E, Rund D. Differences in rhodamine-123 efflux in B-type chronic lymphocytic leukemia suggest possible gender and stage variations in drug-resistance gene activity. Ann Hematol 1998;76:189–194.
  • Overdevest JB, Theodorescu D, Lee JK. Utilizing the molecular gateway: the path to personalized cancer management. Clin Chem 2009;55:684–697.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.