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Letters to the Editor

Dasatinib is effective against optic nerve infiltration of Philadelphia chromosome-positive acute lymphoblastic leukemia

, , , , , , & show all
Pages 1920-1922 | Received 24 Apr 2010, Accepted 14 Jul 2010, Published online: 21 Sep 2010

References

  • O'Hare T, Walters DK, Stoffregen EP, et al In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res 2005;65:4500–4505.
  • Talpaz M, Shah NP, Kantarjian H, et al Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006;354:2531–2541.
  • Porkka K, Koskenvesa P, Lundan T, et al Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia. Blood 2008;112:1005–1012.
  • Pfeifer H, Wassmann B, Hofmann WK, et al Risk and prognosis of central nervous system leukemia in patients with Philadelphia chromosome-positive acute leukemias treated with imatinib mesylate. Clin Cancer Res 2003;9:4674–4681.
  • Leis JF, Stepan DE, Curtin PT, et al Central nervous system failure in patients with chronic myelogenous leukemia lymphoid blast crisis and Philadelphia chromosome positive acute lymphoblastic leukemia treated with imatinib (STI-571). Leuk Lymphoma 2004;45:695–698.
  • Kaikov Y. Optic nerve head infiltration in acute leukemia in children: an indication for emergency optic nerve radiation therapy. Med Pediatr Oncol 1996;26:101–104.

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