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Leukemia & Lymphoma Volume 51, 2010 - Issue 12
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Letters to the Editor

Rituximab-induced life-threatening coagulopathy occurring in a patient with Waldenström macroglobulinemia treated with fludarabine, cyclophosphamide, and rituximab combination

Sylvain PilorgeService d'hématologie, Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital Cochin, Paris, France, and Universite Paris Descartes, Paris 5, France
,
Sophie ParkService d'hématologie, Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital Cochin, Paris, France, and Universite Paris Descartes, Paris 5, France
,
François DreyfusService d'hématologie, Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital Cochin, Paris, France, and Universite Paris Descartes, Paris 5, France
,
Didier BouscaryService d'hématologie, Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital Cochin, Paris, France, and Universite Paris Descartes, Paris 5, France
&
Jerome TamburiniService d'hématologie, Assistance Publique Hôpitaux de Paris (AP-HP), Hôpital Cochin, Paris, France, and Universite Paris Descartes, Paris 5, FranceCorrespondence[email protected]
Pages 2288-2290 | Received 31 Jul 2010, Accepted 07 Sep 2010, Published online: 07 Oct 2010

References

  • Dimopoulos MA, Gertz MA, Kastritis E, et al Update on treatment recommendations from the Fourth International Workshop on Waldenstrom's Macroglobulinemia. J Clin Oncol 2009;27:120–126.
  • Ram R, Ben-Bassat I, Shpilberg O, Polliack A, Raanani P. The late adverse events of rituximab therapy–rare but there! Leuk Lymphoma 2009;50:1083–1095.
  • Eby C. Pathogenesis and management of bleeding and thrombosis in plasma cell dyscrasias. Br J Haematol 2009; 145:151–163.
  • Ram R, Bonstein L, Gafter-Gvili A, Ben-Bassat I, Shpilberg O, Raanani P. Rituximab-associated acute thrombocytopenia: an under-diagnosed phenomenon. Am J Hematol 2009;84:247–250.
  • Pamuk GE, Donmez S, Turgut B, Demir M, Vural O. Rituximab-induced acute thrombocytopenia in a patient with prolymphocytic leukemia. Am J Hematol 2005;78:81.
  • Otrock ZK, Mahfouz RA, Oghlakian GO, Salem ZM, Bazarbachi A. Rituximab-induced acute thrombocytopenia: a report of two cases. Haematologica 2005;90(Suppl.): ECR23.
  • Thachil J, Mukherje K, Woodcock B. Rituximab-induced haemorrhagic thrombocytopenia in a patient with hairy cell leukaemia. Br J Haematol 2006;135:273–274.
  • Kotsianidis I, Goutzouvelidis A, Anastasiades A, et al Severe thrombocytopenia and fibrinolysis mimicking disseminated intravascular coagulation after rituximab infusion. Am J Hematol 2010;85:146.

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