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Research Article

MDM2 SNP309 variation contributes to leukemia risk: meta-analyses based on 7259 subjects

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Pages 2245-2252 | Received 14 Mar 2012, Accepted 03 May 2012, Published online: 12 Jun 2012

References

  • Finch SC. Radiation-induced leukemia: lessons from history. Best Pract Res Clin Haematol 2007;20:109–118.
  • Bjork J, Johansson B, Broberg K, . Smoking as a risk factor for myelodysplastic syndromes and acute myeloid leukemia and its relation to cytogenetic findings: a case-control study. Leuk Res 2009;33:788–791.
  • Lichtman MA. Obesity and the risk for a hematological malignancy: leukemia, lymphoma, or myeloma. Oncologist 2010;15:1083–1101.
  • Alexander FE, Patheal SL, Biondi A, . Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion. Cancer Res 2001;61:2542–2546.
  • Ross JA. Environmental and genetic susceptibility to MLL-defined infant leukemia. J Natl Cancer Inst Monogr 2008;(39):83–86.
  • Mullighan CG. Genetic variation and the risk of acute lymphoblastic leukemia. Leuk Res 2010;34:1269–1270.
  • Zhang MY, Chen FY, Zhong H. Meta-analysis of human leukocyte antigen genetic polymorphisms and susceptibility to chronic myelogenous leukemia in Chinese population. Leuk Res 2011;35: 1564–1570.
  • Ye Z, Song H. Glutathione s-transferase polymorphisms (GSTM1, GSTP1 and GSTT1) and the risk of acute leukaemia: a systematic review and meta-analysis. Eur J Cancer 2005;41:980–989.
  • Guha N, Chang JS, Chokkalingam AP, . NQO1 polymorphisms and de novo childhood leukemia: a HuGE review and meta-analysis. Am J Epidemiol 2008;168:1221–1232.
  • Yan J, Yin M, Dreyer ZE, . A meta-analysis of MTHFR C677T and A1298C polymorphisms and risk of acute lymphoblastic leukemia in children. Pediatr Blood Cancer 2012;58:513–518.
  • Qian X, Cao S, Yang G, . Variant genotypes of MDR1 C3435T increase the risk of leukemia: evidence from 10 case-control studies. Leuk Lymphoma 2012 Jan 3. [Epub ahead of print]
  • Sellick GS, Rudd M, Eve P, . The P2X7 receptor gene A1513C polymorphism does not contribute to risk of familial or sporadic chronic lymphocytic leukemia. Cancer Epidemiol Biomarkers Prev 2004;13:1065–1067.
  • Zhang YD, Tan LN, Zhang XL, . Meta-analysis of cytochrome P4501A1 MspI gene polymorphism and childhood acute leukemia. Biomed Environ Sci 2011;24:683–687.
  • Wickremasinghe RG, Prentice AG, Steele AJ. p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies. Leukemia 2011;25:1400–1407.
  • Wu H, Leng RP. UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation. Cell Cycle 2011;10:1912–1915.
  • Poyurovsky MV, Katz C, Laptenko O, . The C terminus of p53 binds the N-terminal domain of MDM2. Nat Struct Mol Biol 2010;17:982–989.
  • Toledo F, Wahl GM. MDM2 and MDM4: p53 regulators as targets in anticancer therapy. Int J Biochem Cell Biol 2007;39:1476–1482.
  • Bond GL, Hu W, Bond EE, . A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 2004;119:591–602.
  • Munafo MR, Clark TG, Flint J. Assessing publication bias in genetic association studies: evidence from a recent meta-analysis. Psychiatry Res 2004;129:39–44.
  • Egger M, Davey Smith G, Schneider M, . Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629–634.
  • Zenz T, Benner A, Stilgenbauer S. MDM2 promotor polymorphism and disease characteristics in CLL. Leuk Res 2010;34:578–579.
  • Post SM, Pant V, Abbas H, . Prognostic impact of the MDM2SNP309 allele in leukemia and lymphoma. Oncotarget 2010;1: 168–174.
  • Swinney RM, Hsu SC, Hirschman BA, . MDM2 promoter variation and age of diagnosis of acute lymphoblastic leukemia. Leukemia 2005;19:1996–1998.
  • Lahiri O, Harris S, Packham G, . p53 pathway gene single nucleotide polymorphisms and chronic lymphocytic leukemia. Cancer Genet Cytogenet 2007;179:36–44.
  • Phang BH, Linn YC, Li H, . MDM2 SNP309 G allele decreases risk but does not affect onset age or survival of Chinese leukaemia patients. Eur J Cancer 2008;44:760–766.
  • Gryshchenko I, Hofbauer S, Stoecher M, . MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia. J Clin Oncol 2008;26:2252–2257.
  • Shi H, Tan SJ, Zhong H, . Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia. Am J Hum Genet 2009;84:534–541.
  • Kaderi MA, Mansouri M, Zainuddin N, . Lack of association between the MDM2 promoter polymorphism SNP309 and clinical outcome in chronic lymphocytic leukemia. Leuk Res 2010;34:335–339.
  • Asslaber D, Pinon JD, Seyfried I, . microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia. Blood 2010;115:4191–4197.
  • Willander K, Ungerback J, Karlsson K, . MDM2 SNP309 promoter polymorphism, an independent prognostic factor in chronic lymphocytic leukemia. Eur J Haematol 2010;85:251–256.
  • Ellis NA, Huo D, Yildiz O, . MDM2 SNP309 and TP53 Arg72Pro interact to alter therapy-related acute myeloid leukemia susceptibility. Blood 2008;112:741–749.
  • Zenz T, Habe S, Benner A, . The MDM2 - 309 T/G promoter single nucleotide polymorphism does not alter disease characteristics in chronic lymphocytic leukemia. Haematologica 2008;93:1111–1113.
  • Chen YL, Chang YS, Chang JG, . Genotyping of single nucleotide polymorphism in MDM2 genes by universal fluorescence primer PCR and capillary electrophoresis. Anal Bioanal Chem 2009;394:1291–1297.
  • Xiong X, Wang M, Wang L, . Risk of MDM2 SNP309 alone or in combination with the p53 codon 72 polymorphism in acute myeloid leukemia. Leuk Res 2009;33:1454–1458.
  • Do TN, Ucisik-Akkaya E, Davis CF, . TP53 R72P and MDM2 SNP309 polymorphisms in modification of childhood acute lymphoblastic leukemia susceptibility. Cancer Genet Cytogenet 2009;195:31–36.
  • Phillips CL, Gerbing R, Alonzo T, . MDM2 polymorphism increases susceptibility to childhood acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer 2010;55:248–253.
  • Dong HJ, Fang C, Fan L, . MDM2 promoter SNP309 is associated with an increased susceptibility to chronic lymphocytic leukemia and correlates with MDM2 mRNA expression in Chinese patients with CLL. Int J Cancer 2012;130:2054–2061.
  • Thakkinstian A, McElduff P, D’Este C, Duffy D, Attia J. A method for meta-analysis of molecular association studies. Stat Med 2005;24: 1291–1306.
  • Tobias A. Assessing the influence of a single study in the meta-analysis estimate. Stata Techn Bull 1999;8:15–17.
  • Cai X, Yang M. The functional MDM2 T309G genetic variant but not P53 Arg72Pro polymorphism is associated with risk of sarcomas: a meta-analysis. J Cancer Res Clin Oncol 2012;138:555–561.
  • Li Y, Zhao H, Sun L, . MDM2 SNP309 is associated with endometrial cancer susceptibility: a meta-analysis. Hum Cell 2011;24: 57–64.
  • Liu GY, Jiang DK, Shen SQ, . MDM2 SNP309T > G polymorphism with hepatocellular carcinoma risk: a meta-analysis. Arch Med Res 2011;42:149–155.
  • Economopoulos KP, Sergentanis TN. Differential effects of MDM2 SNP309 polymorphism on breast cancer risk along with race: a meta-analysis. Breast Cancer Res Treat 2010;120:211–216.
  • Cao X, Zhang T, Zhao Z, . MDM2 SNP309 polymorphism and colorectal cancer risk: a meta-analysis. DNA Cell Biol 2012;31:355–359.
  • Liu J, Zheng Y, Lei D, . MDM2 309T > G polymorphism and risk of squamous cell carcinomas of head and neck: a meta-analysis. Asian Pac J Cancer Prev 2011;12:1899–1903.
  • Swinney RM, Beuten J, Collier AB 3rd, . Polymorphisms in CYP1A1 and ethnic-specific susceptibility to acute lymphoblastic leukemia in children. Cancer Epidemiol Biomarkers Prev 2011;20:1537–1542.
  • So CC, Wan TS, Chow JL, . A single-center cytogenetic study of 629 Chinese patients with de novo acute myeloid leukemia--evidence of major ethnic differences and a high prevalence of acute promyelocytic leukemia in Chinese patients. Cancer Genet 2011;204:430–438.
  • Bhatia S, Sather HN, Heerema NA, . Racial and ethnic differences in survival of children with acute lymphoblastic leukemia. Blood 2002;100:1957–1964.
  • Clarke CA, Glaser SL, Gomez SL, . Lymphoid malignancies in U.S. Asians: incidence rate differences by birthplace and acculturation. Cancer Epidemiol Biomarkers Prev 2011;20:1064–1077.
  • Hunger SP, Raetz EA, Loh ML, . Improving outcomes for high-risk ALL: translating new discoveries into clinical care. Pediatr Blood Cancer 2011;56:984–993.
  • Bonaventure A, Goujon-Bellec S, Rudant J, . Maternal smoking during pregnancy, genetic polymorphisms of metabolic enzymes, and childhood acute leukemia: the ESCALE study (SFCE). Cancer Causes Control 2012;23:329–345.
  • Milne E, Greenop KR, Scott RJ, . Parental prenatal smoking and risk of childhood acute lymphoblastic leukemia. Am J Epidemiol 2012;175:43–53.

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