References
- Damle RN, Wasil T, Fais F, . Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999;94:1840–1847.
- Hamblin TJ, Davis Z, Gardiner A, . Unmutated ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999;94:1848–1854.
- Dohner H, Stilgenbauer S, Benner A, . Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 2000;343: 1910–1916.
- Orchard JA, Ibbotson RE, Davis Z, . ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet 2004;363: 105–111.
- Rassenti LZ, Huynh L, Toy TL, . ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. N Engl J Med 2004;351:893–901.
- Juliusson G, Oscier DG, Fitchett M, . Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities. N Engl J Med 1990;323:720–724.
- Dicker F, Schnittger S, Haferlach T, . Immunostimulatory oligonucleotide-induced metaphase cytogenetics detect chromosomal aberrations in 80% of CLL patients: a study of 132 CLL cases with correlation to FISH, IgVH status, and CD38 expression. Blood 2006; 108:3152–3160.
- Put N, Konings P, Rack K, . Improved detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide and interleukin-2 stimulation: a Belgian multicentric study. Genes Chromosomes Cancer 2009;48: 843–853.
- Schwaenen C, Nessling M, Wessendorf S, . Automated array-based genomic profiling in chronic lymphocytic leukemia: development of a clinical tool and discovery of recurrent genomic alterations. Proc Natl Acad Sci USA 2004;101:1039–1044.
- Sargent R, Jones D, Abruzzo LV, . Customized oligonucleotide array-based comparative genomic hybridization as a clinical assay for genomic profiling of chronic lymphocytic leukemia. J Mol Diagn 2009;11:25–34.
- Kujawski L, Ouillette P, Erba H, . Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia. Blood 2008;112:1993–2003.
- Gunnarsson R, Staaf J, Jansson M, . Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia–a comparative study of four differently designed, high resolution microarray platforms. Genes Chromosomes Cancer 2008;47:697–711.
- Kay NE, Eckel-Passow JE, Braggio E, . Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy. Cancer Genet Cytogenet 2010;203:161–168.
- Ouillette P, Collins R, Shakhan S, . Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia. Blood 2011;118:3051–3061.
- Ouillette P, Erba H, Kujawski L, . Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14. Cancer Res 2008;68:1012–1021.
- Chapiro E, Leporrier N, Radford-Weiss I, . Gain of the short arm of chromosome 2 (2p) is a frequent recurring chromosome aberration in untreated chronic lymphocytic leukemia (CLL) at advanced stages. Leuk Res 2010;34:63–68.
- Mosca L, Fabris S, Lionetti M, . Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion. Clin Cancer Res 2010;16: 5641–5653.
- Parker H, Rose-Zerilli MJ, Parker A, . 13q deletion anatomy and disease progression in patients with chronic lymphocytic leukemia. Leukemia 2011;25:489–497.
- Rinaldi A, Mian M, Kwee I, . Genome-wide DNA profiling better defines the prognosis of chronic lymphocytic leukaemia. Br J Haematol 2011;154:590–599.
- Rodriguez AE, Robledo C, Garcia JL, . Identification of a novel recurrent gain on 20q13 in chronic lymphocytic leukemia by array CGH and gene expression profiling. Ann Oncol 2012;23:2138–2146.
- Higgins RA, Gunn SR, Robetorye RS. Clinical application of array-based comparative genomic hybridization for the identification of prognostically important genetic alterations in chronic lymphocytic leukemia. Mol Diagn Ther 2008;12:271–280.
- Maciejewski JP, Tiu RV, O’Keefe C. Application of array-based whole genome scanning technologies as a cytogenetic tool in haematological malignancies. Br J Haematol 2009;146:479–488.
- Gunn SR, Mohammed MS, Gorre ME, . Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic leukemia. J Mol Diagn 2008;10:442–451.
- Hagenkord JM, Monzon FA, Kash SF, . Array-based karyotyping for prognostic assessment in chronic lymphocytic leukemia: performance comparison of affymetrix 10K2.0, 250K nsp, and SNP6.0 arrays. J Mol Diagn 2010;12:184–196.
- Lehmann S, Ogawa S, Raynaud SD, . Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia. Cancer 2008;112:1296–1305.
- Tyybakinoja A, Vilpo J, Knuutila S. High-resolution oligonucleotide array-CGH pinpoints genes involved in cryptic losses in chronic lymphocytic leukemia. Cytogenet Genome Res 2007;118:8–12.
- Kolquist KA, Schultz RA, Slovak ML, . Evaluation of chronic lymphocytic leukemia by oligonucleotide-based microarray analysis uncovers novel aberrations not detected by FISH or cytogenetic analysis. Mol Cytogenet 2011;4:25.
- O’Malley DP, Giudice C, Chang AS, . Comparison of array comparative genomic hybridization (aCGH) to FISH and cytogenetics in prognostic evaluation of chronic lymphocytic leukemia. Int J Lab Hematol 2011;33:238–244.
- Gunnarsson R, Isaksson A, Mansouri M, . Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients. Leukemia 2010;24:211–215.
- Delgado J, Aventin A, Briones J, . The use of tetradecanoylphorbol acetate-stimulated peripheral blood cells enhances the prognostic value of interphase fluorescence in situ hybridization in patients with chronic lymphocytic leukemia. Genes Chromosomes Cancer 2010;49:327–332.
- Catovsky D, Richards S, Matutes E, . Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 trial): a randomised controlled trial. Lancet 2007;370:230–239.
- Tam CS, Shanafelt TD, Wierda WG, . De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: The M. D. Anderson and Mayo Clinic experience. Blood 2009;114: 957–964.
- Oscier D, Wade R, Davis Z, . Prognostic factors identified three risk groups in the LRF CLL4 trial, independent of treatment allocation. Haematologica 2010;95:1705–1712.
- Delgado J, Espinet B, Oliveira AC, . Chronic lymphocytic leukaemia with 17p deletion: a retrospective analysis of prognostic factors and therapy results. Br J Haematol 2012 Jan 9. [Epub ahead of print]
- Dal Bo M, Rossi FM, Rossi D, . 13q14 deletion size and number of deleted cells both influence prognosis in chronic lymphocytic leukemia. Genes Chromosomes Cancer 2011;50:633–643.
- Gunnarsson R, Mansouri L, Isaksson A, . Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia. Haematologica 2011;96:1161–1169.
- Forconi F, Rinaldi A, Kwee I, . Genome-wide DNA analysis identifies recurrent imbalances predicting outcome in chronic lymphocytic leukaemia with 17p deletion. Br J Haematol 2008;143: 532–536.