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Commentary

Cerebrospinal fluid analysis by flow cytometry in acute lymphoblastic leukemia: is it all that it is cracked up to be?

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References

  • Larson RA, Dodge RK, Burns CP, et al. A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: Cancer and leukemia group B study 8811. Blood 1995;85:2025–2037.
  • Bleyer WA, Poplack DA. Prophylaxis and treatment of leukemia in the central nervous system and other sanctuaries. Semin Oncol 1985;12:131–148.
  • Cortes J, O’Brien SM, Pierce S, et al. The value of high-dose systemic chemotherapy and intrathecal therapy for central nervous system prophylaxis in different risk groups of adult acute lymphoblastic leukemia. Blood 1995;86:2091–2097.
  • Lazarus HM, Richards SM, Chopra R, et al. Central nervous system involvement in adult lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL XII/ECOG E2993. Blood 2006;108:465–472.
  • Omura GA, Moffitt S, Vogler WR, et al. Combination chemotherapy of adult acute lymphoblastic leukemia with randomized central nervous system prophylaxis. Blood 1980;55:199–204.
  • Suprapaneni UR, Cortes JE, Thomas D, et al. Central nervous system relapse in adults with acute lymphoblastic leukemia. Cancer 2002;94:465–472.
  • Reman O, Pigneux A, Huguet F, et al. Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis and/or at first relapse: results from the GET-LALA group. Leuk Res 2008;32:1741–1750.
  • Kantarjian HM, O’Brien S, Smith TL, et al. Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia. J Clin Oncol 2000;18:547–561.
  • Pui CH, Cheng C, Leung W, et al. Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. N Engl J Med 2003;349:640–649.
  • Pinkel D, Woo S. Prevention and treatment of meningeal leukemia in children. Blood 1994;84:355–366.
  • Mahmoud HH, Rivera GK, Hancock ML, et al. Low leukocyte counts with blast cells in cerebrospinal fluid of children with newly diagnosed acute lymphoblastic leukemia. N Engl J Med 1993;329: 314–319.
  • Gilchrist GS, Tubergen DG, Sather HN, et al. Low numbers of CSF blasts at diagnosis do not predict the development of CNS leukemia in children with intermediate-risk acute lymphoblastic leukemia: A Children's Cancer Group report. J Clin Oncol 1994;12:2594–2600.
  • van der Berg H, Vet R, den Ouden E, et al. Significance of lymphoblast in cerebrospinal fluid in newly diagnosed pediatric acute lymphoblastic malignancies with bone marrow involvement: Possible benefit of dexamethasone. Med Pediatr Oncol 1995;25:22–27.
  • Burger B, Zimmermann M, Mann G, et al. Diagnostic cerebrospinal fluid examination in children with acute lymphoblastic leukemia: significance of low leukocyte counts with blast or traumatic lumbar puncture. J Clin Oncol 2003;21:184–188.
  • Mitri Z, Siddiqui MT, El Rassi F, et al. Sensitivity and specificity of cerebrospinal fluid flow cytometry for the diagnosis of leukemic meningitis in acute lymphoblastic leukemia/lymphoma. Leuk Lymphoma 2014;55:1498–1500. doi:10.3109/10428194.2013.852667.
  • Subira D, Castanon S, Roman A, et al. Flow cytometry and the study of central nervous disease in patients with acute leukaemia. Br J Haematol 2001;112:381–384.
  • Sayed D, Badrawy H, Ali AM, et al. Immunophenotyping and immunoglobulin heavy chain gene rearrangement analysis in cerebrospinal fluid of paediatric patients with acute lymphoblastic leukaemia. Leuk Res 2009;33:655–661.
  • Quijano S, Lopez A, Manuel SL, et al. Spanish group for the study of CNS disease in NHL. Identification of leptomeningeal disease in aggressive B-cell non-Hodgkin's lymphoma: improved sensitivity of flow cytometry. J Clin Oncol 2009;27:1462–1469.
  • Hegde U, Filie A, Little RF, et al. High incidence of occult leptomeningeal disease detected by flow cytometry in newly diagnosed aggressive B-cell lymphomas at risk for central nervous system involvement: the role of flow cytometry versus cytology. Blood 2005;105:496–502.
  • Di Noto R, Scalia G, Abate G, et al. Critical role of multi-dimensional flow cytometry in detecting occult leptomeningeal disease in newly diagnosed aggressive B-cell lymphomas. Leuk Res 2008;32:1196–1199.
  • Glass JJP, Melamed M, Chernik NL, et al. Malignant cells in cerebrospinal fluid: the meaning of a positive CSF cytology. Neurology 1979;29:1369–1375.
  • Stewart DJ, Keating MJ, McCredie KB, et al. Natural history of central nervous system acute leukemia in adults. Cancer 1981;47:184–196.
  • Wasserstrom WR, Glass JP, Posner JB. Diagnosis and treatment of leptomeningeal metastases from solid tumours: experience with 90 patients. Cancer 1982;49:759–772.
  • DeAngelis LM, Cairncross JB. A better way to find tumor in the CSF?Neurology 2002;58:339–340.
  • de Graaf M, van den Broek P, Kraan J, et al. Addition of serum-containing medium to cerebrospinal fluid prevents cellular loss over time. J Neurol 2011;258:1507–1512.
  • Greig B, Stetler-Stevenson M, Lea J. Stabilization media increases recovery in paucicellular cerebrospinal fluid specimens submitted for flow cytometry testing. Cytometry B Clin Cytom 2013 May 14. [Epub ahead of print]
  • de Graaf M, de Jongste AH, Kraan J, et al. Flow cytometric characterization of cerebrospinal fluid cells. Cytometry B Clin Cytom 2011;80:271–281.
  • Craig FE, Ohori P, Gorrill TS, et al. Flow cytometric immunophenotyping of cerebrospinal fluid specimens. Am J Clin Pathol 2011;135:22–34.
  • Marveska D, to Loo WM, Kamps WA, et al. Prognostic significance of blasts in the cerebrospinal fluid without pleocytosis or a traumatic lumbar puncture in children with acute lymphoblastic leukaemia: the experience of the Dutch Childhood Oncology Group. J Clin Oncol 2006;24:2332–2336.
  • Gajjar A, Harrison PL, Sandlund JT. et al. Traumatic lumbar puncture at diagnosis adversely affects outcome in childhood acute lymphoblastic leukaemia. Blood 2000;96:3381–3384.

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