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Letter to the Editor

Lenalidomide differently modulates CD20 antigen surface expression on chronic lymphocytic leukemia B-cells

, , , , , , , , & show all
Pages 2458-2459 | Received 03 May 2014, Accepted 13 Dec 2014, Published online: 29 Jan 2015

References

  • Kater AP, Tonino SH, Egle A, et al. How does lenalidomide target the chronic lymphocytic leukemia microenvironment? Blood 2014;124:2184–2189.
  • Giannopoulos K, Mertens D, Stilgenbauer S. Treating chronic lymphocytic leukemia with thalidomide and lenalidomide. Expert Opin Pharmacother 2011;12:2857–2864.
  • Ramsay AG, Gribben JG. Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immuno-modulatory drug. Haematologica 2009;94:1198–1202.
  • Weiner GJ. Rituximab: mechanism of action. Semin Hematol 2010;47:115–123.
  • D’Arena G, Musto P, Cascavilla N, et al. Quantitative flow cytometry for the differential diagnosis of leukemic B-cell chronic lymphoproliferative disorders. Am J Hematol 2000;64:275–281.
  • Badoux XC, Keating MJ, Wen S, et al. Phase II study of lenalidomide and rituximab as salvage therapy for patients with relapsed or refractory chronic lymphocytic leukemia. J Clin Oncol 2013;31:584–591.
  • Lapalombella R, Yu B, Triantafillou G, et al. Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells. Blood 2008;112:5180–5189.
  • Reddy N, Hernandez-Ilizaliturri FJ, Deeb G, et al. Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumor activity of rituximab in vivo. Br J Haematol 2007;140:36–45.
  • Gaidarova S, Mendy D, Heise C, et al. Lenalidomide induces capping of CD20 and cytoskeleton proteins to enhance rituximab immune recognition of malignant B-cells. Blood 2010;116(Suppl. 1): Abstract 2845.

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