Advanced search
Publication Cover
Leukemia & Lymphoma Volume 57, 2016 - Issue 9
Submit an article Journal homepage
614
Views
23
CrossRef citations to date
0
Altmetric
Original Articles: Clinical

Cutaneous involvement in multiple myeloma: a multi-institutional retrospective study of 53 patients

Artur JurczyszynJagiellonian University Medical College, Cracow, Poland; Correspondence[email protected]
,
Magdalena Olszewska-SzopaWroclaw Medical University, Wroclaw, Poland;
,
Vania HungriaSanta Casa Medical School, Sao Paulo, Brazil;
,
Edvan CrusoeSanta Casa Medical School, Sao Paulo, Brazil;
,
Tomas PikaUniversity Hospital Olomouc, Olomouc, Czech Republic;
,
Michel DelforgeDepartment of Hematology University Hospitals Leuven, Belgium;
,
Xavier LeleuHopital La Miletrie, CHU Poitiers, France;
,
Leo RascheDepartment of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany;
,
Ajay K. NookaWinship Cancer Institute, Emory University, Atlanta, GA, USA;
,
Agnieszka Druzd-SitekMaria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland;
,
Jan WalewskiMaria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland;
,
Julio DavilaHospital Universitario De Salamanca, Salamanca, Spain;
,
Jo CaersCentre Hospitalier Universitaire De Liege, Liege, Belgium;
,
Vladimir MaisnarDepartment of Medicine – Haematology, Hradec Kralove, Czech Republic;
,
Morie GertzDivision of Hematology, Mayo Clinic, Rochester, MN, USA;
,
Massimo GentileHematology Unit, Department of Onco-Hematology, A.O. of Cosenza, Cosenza, Italy;
,
Dorotea FantlHospital Italiano De Buenos Aires, Buenos Aires, Argentina;
,
Giuseppe MeleHaematology, Ospedale A. Perrino, Brindisi, Italy;
,
David H. VesoleJohn Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ, USA;
,
Andrew J. YeeMassachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA;
,
Chaim ShustikRoyal Victoria Hospital, McGill University, Montreal, Canada;
,
Suzanne LentzschColumbia University Medical Center, New York, NY, USA;
,
Sonja ZweegmanVU University Medical Center, Amsterdam, the Netherlands;
,
Alessandro GozzettiAzienda Ospedaliera Universitaria Senese, Siena, Italy;
,
Aleksander B. SkotnickiJagiellonian University Medical College, Cracow, Poland;
&
Jorge J. CastilloDana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
 show all
Pages 2071-2076 | Received 13 Nov 2015, Accepted 29 Nov 2015, Published online: 04 Jan 2016

References

  • An N, Li X, Shen M, et al. Analysis of clinical features, treatment response, and prognosis among 61 elderly newly diagnosed multiple myeloma patients: a single-center report. World J Surg Oncol. 2015;13:239
  • Deng S, Xu. Y, An. G, et al. Features of extramedullary disease of multiple myeloma: high frequency of p53 deletion and poor survival: a retrospective single-center study of 834 cases. Clin Lymphoma Myeloma Leuk. 2015;15:286–291.
  • Lee SE, Kim JH, Jeon YW, et al. Impact of extramedullary plasmacytomas on outcomes according to treatment approach in newly diagnosed symptomatic multiple myeloma. Ann Hematol. 2015;94:445–452.
  • Short KD, Rajkumar SV, Larson D, et al. Incidence of extramedullary disease in patients with multiple myeloma in the era of novel therapy, and the activity of pomalidomide on extramedullary myeloma. Leukemia 2011;25:906–908.
  • Hedinger E. ZurFrage des Plasmacytomas. Frankfurter Zeitschrift Für Pathologie. 1911;7:343–350.
  • Rodriguez JM, Lam S, Silber R. Multiple myeloma with cutaneous involvement. JAMA 1977;237:2625–2626.
  • Shpilberg O, Yaniv R, Levy Y, et al. Huge cutaneous plasmacytomas complicating multiple myeloma. Clin Exp Dermatol. 1994;19:324–326.
  • Patel K, Carrington PA, Bhatnagar S, et al. IgD myeloma with multiple cutaneous plasmacytomas. Clin Lab Haematol. 1998;20:53–55.
  • Güvenç B, Canataroğlu A, Gümürdülü Y, et al. Multiple myeloma with skin involvement. J Eur Acad Dermatol Venereol. 2001;15:328–329.
  • Santos G, Sousa L, Fernandes T, et al. Case for diagnosis. Cutaneous involvement associated to multiple myeloma. Anais Brasileiros De Dermatologia 2014;89:173–174.
  • Araújo, C, Marques, H, Fernandes, JC, et al. Cutaneous plasmacytomas secondary to nonsecretory multiple myeloma. J Dermatol Clin Res. 2014;2:1022.
  • Serefhanoglu S, Haznedaroglu IC, Goker H, et al. Multiple bulky cutaneous plasmacytomas with CNS relapse without bone marrow involvement during the course of a lambda light chain myeloma. Onkologie 2009;32:662–664.
  • Shah A, Klimo P, Worth A. Multiple myeloma first observed as multiple cutaneous plasmacytomas. Arch Dermatol. 1982;118:922–924.
  • Requena L. Afectación cutánea específica en pacientes con mieloma multiple. Estudio clínico-patológico, inmunohistoquímico y citogenético de 40 casos. Actas Dermosifiliográficas. 2005;96:424–440.
  • Messeguer F, Llombart B, Sanmartín O, et al. Cutaneous involvement in multiple myeloma: report of two cases. J Dermatol. 2012;39:806–808.
  • Nguyen SK, Dagnault A. Radiotherapy for multiple myeloma with skin involvement. Curr Oncol. 2010;17: 74–77.
  • Kato N, Kimura K, Yasukawa K, et al. Metastatic cutaneous plasmacytoma: a case report associated with IgA lambda multiple myeloma and a review of the literature of metastatic cutaneous plasmacytomas associated with multiple myeloma and primary cutaneous plasmacytomas. J Dermatol. 1999;26:587–594.
  • Bayer-Garner IB, Joseph L, Sanderson RD, et al. Expression of syndecan-1 is a sensitive marker for cutaneous plasmacytoma. J Cutan Pathol. 2003;30:18–22.
  • Requena L, Kutzner H, Palmedo G, et al. Cutaneous involvement in multiple myeloma: a clinicopathologic, immunohistochemical, and cytogenetic study of 8 cases. Arch Dermatol. 2003;139:475–486.
  • Rajkumar SV, Fonseca R, Lacy MQ, et al. Plasmablastic morphology is an independent predictor of poor survival after autologous stem-cell transplantation for multiple myeloma. J Clin Oncol. 1999;17:1551–1557.
  • Subbiah S, O’Connell F, Kobraei KB, et al. Unusual multiple myeloma cutaneous manifestation following nonmyeloablative allogeneic stem cell transplantation. Clin Adv Hematol Oncol. 2009;7:800–802.
  • Rasche L, Strifler S, Duell J, et al. The lymphoma-like polychemotherapy regimen “Dexa-BEAM” in advanced and extramedullary multiple myeloma. Ann Hematol. 2014;93:1207–1214.
  • Karasawa T, Matsumoto T, Akiyama M. Metastatic skin lesions of multiple myeloma presenting as two extraordinarily large subcutaneous tumors. Int J Dermatol. 2013;52:1568–1570.
  • Karimkhani C, Smith C. Extraosseous extension of multiple myeloma: a cutaneous herald to systemic disease. J Am Acad Dermatol. 2014;71:e73–e74.
  • Liu J, Bakst R, Phelps R, et al. Radiation therapy for secondary cutaneous plasmacytomas. Case Rep Hematol. 2013;2013:739230

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.