Advanced search
Publication Cover
Leukemia & Lymphoma Volume 57, 2016 - Issue 8
Submit an article Journal homepage
280
Views
2
CrossRef citations to date
0
Altmetric
Correspondence

The effect of FLT3-ITD and NPM1 mutation on survival in intensively treated elderly patients with cytogenetically normal acute myeloid leukemia

Armin RashidiBone Marrow Transplantation and Leukemia Section, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA; Correspondence[email protected]
,
Ofir WolachDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA;
,
Areej El-JawahriBone Marrow Transplant Unit, Massachusetts General Hospital, Boston, MA, USA
,
Vincent T. HoBone Marrow Transplant Unit, Massachusetts General Hospital, Boston, MA, USA
,
John F. DiPersioBone Marrow Transplantation and Leukemia Section, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA;
,
Robert SoifferBone Marrow Transplant Unit, Massachusetts General Hospital, Boston, MA, USA
,
Richard M. StoneDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA;
&
Yi-Bin ChenBone Marrow Transplant Unit, Massachusetts General Hospital, Boston, MA, USA
 show all
Pages 1977-1979 | Received 18 Jan 2016, Accepted 28 Feb 2016, Published online: 22 Mar 2016

References

  • McGregor AK, Moulton D, Bown N, et al. Incidence and outcomes for adults diagnosed with acute myeloid leukemia in the north of England: a real world study. Leuk Lymphoma. 2016, in press.
  • Hefazi M, Siddiqui M, Patnaik M, et al. Prognostic impact of combined NPM1+/FLT3-genotype in patients with acute myeloid leukemia with intermediate risk cytogenetics stratified by age and treatment modalities. Leuk Res. 2016, in press.
  • Brunet S, Labopin M, Esteve J, et al. Impact of FLT3 internal tandem duplication on the outcome of related and unrelated hematopoietic transplantation for adult acute myeloid leukemia in first remission: a retrospective analysis. J Clin Oncol. 2012;30:735–741.
  • Schmid C, Labopin M, Socie G, et al. Outcome of patients with distinct molecular genotypes and cytogenetically normal AML after allogeneic transplantation. Blood. 2015;126:2062–2069.
  • Ostronoff F, Othus M, Lazenby M, et al. Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: a SWOG and UK National Cancer Research Institute/Medical Research Council report. J Clin Oncol. 2015;33:1157–1164.
  • Rashidi A, Ebadi M, Colditz GA, et al. Outcomes of allogeneic stem cell transplantation in elderly patients with acute myeloid leukemia: a systematic review and meta-analysis. Biol Blood Marrow Transplant. 2016, in press.
  • Chen YB, Li S, Lane AA, et al. Phase I trial of maintenance sorafenib after allogeneic hematopoietic stem cell transplantation for fms-like tyrosine kinase 3 internal tandem duplication acute myeloid leukemia. Biol Blood Marrow Transplant. 2014;20:2042–2048.
  • Medeiros BC, Satram-Hoang S, Hurst D, et al. Big data analysis of treatment patterns and outcomes among elderly acute myeloid leukemia patients in the United States. Ann Hematol. 2015;94:1127–1138.
  • Ustun C, Lazarus HM, Weisdorf D. To transplant or not: a dilemma for treatment of elderly AML patients in the twenty-first century. Bone Marrow Transplant. 2013;48:1497–1505.
  • Lang K, Earle CC, Foster T, et al. Trends in the treatment of acute myeloid leukaemia in the elderly. Drugs Aging. 2005;22:943–955.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.