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Leukemia & Lymphoma Volume 6, 1991 - Issue 1
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Original Article

Phase II Trial of Fludarabine Phosphate in Multiple Myeloma Using a Loading Dose and Continuous Infusion Schedule

Stuart M. Lichtman From: Don Monti Division of Oncology, Department of Medicine, Department of Medicine, North Shore University Hospital-Cornell University Medical College, Manhasset, NY, Cornell University Medical College, New York
,
Abraham Mittelman Division of Neoplastic Diseases, Department of Medicine, New York Medical College, Valhalla, New York, USA
,
Daniel R. Budman From: Don Monti Division of Oncology, Department of Medicine, Department of Medicine, North Shore University Hospital-Cornell University Medical College, Manhasset, NY, Cornell University Medical College, New York
,
Carmelo A. Puccio Division of Neoplastic Diseases, Department of Medicine, New York Medical College, Valhalla, New York, USA
,
Hoo G. Chun Investigational Drug Branch, Cancer Therapy Evaluation Program Division of Cancer Treatment, National Cancer Institute, Bethesda, Maryland, USA; Division of Neoplastic Diseases, New York Medical College, Valhalla, New York
,
Steven L. Allen From: Don Monti Division of Oncology, Department of Medicine, Department of Medicine, North Shore University Hospital-Cornell University Medical College, Manhasset, NY, Cornell University Medical College, New York
,
Tauseef Ahmed Division of Neoplastic Diseases, Department of Medicine, New York Medical College, Valhalla, New York, USA
&
Zalmen A. Arlin Division of Neoplastic Diseases, Department of Medicine, New York Medical College, Valhalla, New York, USA
 show all
Pages 61-63 | Received 02 May 1991, Published online: 01 Jul 2009

References

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  • Hutton J. J., Von D. D., Kuhn J. Phase I clinical investigation of 9-B-D-arabinofuranoslyl-2-fluoroadenine 5'-monophosphate (NSC 312887), a new purine antimetabolite. Cancer Res 1984; 44: 4183–4186
  • Grever M. R., Kraut E. H., Neidhart J. A. 2-Fluoro-ara-AMP: A phase I clinical investigation. Invest New Drugs 1984; 2: 116
  • Leiby J. M., Grever M. R., Staubus A. E. Phase I clinical investigation of fludarabine phosphate by a loading dose and continuous-infusion schedule. J. Natl. Cancer. Inst 1988; 80: 447–449
  • Keating M. J., Kantarjian H., Talpaz M. Fludarabine: A new agent with major activity against chronic lymphocytic leukemia. Blood 1989; 74: 19–25
  • Puccio C., Mittelman A., Lichtman S. Phase II study of Fludarabine Phosphate (FAMP) in Chronic Lymphocytic Leukemia (CLL). Proc. Am. Soc. Clin. Onc 1990; 9: 796a
  • Hochster H., Cassileth P. Fludarabine phosphate therapy of non-Hodgkin's lymphoma. Seminars Oncology 1990; 17: 63–65, (Suppl 8)
  • Kantarjian H. M., Redman J. R., Keating M. J. Fludarabine phosphate therapy of other lymphoid malignancies. Seminars Oncology 1991; 17: 66–70, (Suppl 8)
  • Mittelman A., Ashikari R., Ahmed T. Phase II trials of 2-fluoro-ara-AMP (fludarabine phosphate) in patients (pts) with advanced breast cancer. Proc Am Assoc Cancer Res 1985; 26: 170
  • Carpenter J. T., Jr., Vogel C. L., Wang G. Phase II evaluation of fludarabine in patients with metastatic breast cancer: a Southeastern Cancer Study Group Trial. Cancer Treat Rep 1986; 70: 1235–1236
  • Harvey W. H., Fleming T. R., Von Hoff D. D. Phase II study of fludarabine phosphate in previously untreated patients with colorectal carcinoma: a Southwest Oncology Group Study. Cancer Treat Rep 1987; 71: 1319–1320
  • Weiss G. R., Growley J., Von Hoff D. D. Phase II study of fludarabine phosphate for the treatment of advanced non small cell carcinoma of the lung: a Southwest Oncology Group Study. Cancer Treat Rep 1986; 70: 1123–1124
  • Weiss G. B., Metch B., Von Hoff D. D. Phase II trial of fludarabine phosphate in patients with head and neck cancer: a Southwest Oncology Group Study. Cancer Treat Rep 1987; 71: 1313–1314
  • Balducci L., Blumenstein B., Von Hoff D. D. Evaluation of fludarabine phosphate in renal cell carcinoma: a Southwest Oncology Group Study. Cancer Treat Rep 1987; 71: 543–544
  • Kavanagh J. J., Stringer C. A., Copeland L. J. Phase II trial of fludarabine in patients with epithelial ovarian cancer. Cancer Treat Rep 1986; 70: 425–426
  • Kraut E. H., Crowley J. J., Grever M. R. Phase II study of fludarabine phosphate in multiple myeloma. Invest New Drugs 1990; 8: 199–200

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