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Original Article

Molecular Mechanisms in the Evolution of Chronic Myelocytic Leukemia

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Pages 283-287 | Received 30 Nov 1991, Published online: 01 Jul 2009

References

  • Nowell P. C., Hungerford D. A. A minute chromosome in human granulocytic leukemia. J. Natl. Cancer Inst. 1960; 25: 85–109
  • Rowley J. D. A new consistent chromosomal abnormality in chronic myelogenous leukemia identified by quinacrine fluorescence and giemsa staining. Nature 1973; 243: 290–293
  • Bartram C. R., de Klein A., Hagemeijer A., van Agthoven T., Gewits van Kessel A., Bootsma D., Grosveld G., Ferguson-Smith M. A., Davies T., Stone M., Heisterkamp N., Stephenson J. R., Groffen J. Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukemia. Nature 1983; 306: 277–280
  • Groffen J., Stephenson J. R., Heisterkamp N., de Klein A., Bartram C. R., Grosveld G. Philadelphia chromosome breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 1984; 36: 93–99
  • Collins S. J., Kubonishi I., Miyoshi I., Groudine M. Altered transcription of the c-abl oncogene in K-562 and other chronic myelogenous leukemia cells. Science 1984; 225: 72–74
  • Shtivelman E., Lifshitz B., Gale R. P., Cannani E. Fused transcript of abl and bcr genes in chronic myelogenous leukemias. Nature 1985; 315: 550–554
  • Ben Neriah Y., Daley G. Q., Mes-Masson A. M., Witte O. N., Baltimore D. The chronic myelogenous leukemia specific p210 protein is the product of the bcr/abl hybrid gene. Science 1986; 223: 212–214
  • Konopka J. B., Watanabe S. M., Witte O. N. Alteration of human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Cell 1984; 37: 1035–42
  • Hermans A., Heisterkamp N., von Lindern M., van Baal S., Meijer D., van der Plas D., Wiedemann L. M., Groffen G., Bootsma D., Grosveld G. Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia. Cell 1987; 51: 33–40
  • Clark S. S., McLaughlin J., Crist W. M., Champlin R., Witte O. N. Unique forms of the abl tyrosine kinase distinguish Ph1-positive CML from Ph1-positive ALL. Science 1987; 235: 85–88
  • Fitzgerald P. H., Beard M. E., Morris C. M., Heaton D. C., Reeve A. E. Ph1 negative chronic myeloid leukemia. British Journal of Haematology 1987; 66: 311–314
  • Daley G. Q., Van Etten R. A., Baltimore D. Induction of chronic myelogenous leukemia in mice by the p210 bcr-abl gene of the Philadelphia chromosome. Science 1990; 247: 824–830
  • Mc Laughlin J., Chianese E., Witte O. N. In vitro transformation of immature hematopoetic cells by the p210 BCR/ABL oncogene products of the Philadelphia chromosome. Proc. Natl. Acad, Sci, USA 1987; 84: 6558–6562
  • Muehleck S. D., McKenna R. W., Arthur D. C., Parkin J. L., Brunning R. D. Transformation of chronic myelogenous leukemia: clinical, morphologic and cytogenetic features. J. Clin. Pathol. 1984; 82: 1–14
  • Dreazen O., Cannani E., Gale R. P. Molecular biology of chronic myelogenous leukemia. Sem. Hem. 1988; 25: 35–48
  • Shtivelman E., Gale R. P., Dreazen O., Berrebi A., Zaizov R., Kubonishi I., Miyoshi I., Cannani E. bcr-abl RNA in patients with chronic myelogenous leukemia. Blood 1987; 69: 971–973
  • Liu E., Hielle B., Bishop J. M. Transforming genes in chronic myelogenous leukemia. Proc. Natl. Acad. Sci, USA 1988; 85: 1952–1956
  • Mc Carthy D. M., Goldman J. M., Rasool F. V., Graham S. V., Bimie G. D. Genomic alterations involving the c-myc proto oncogene during the evolution of a case of chronic granulocytic leukemia. Lancet 1984; ii: 1362–1365
  • Ahuja H., Bar-Eli M., Advani S. H., Benchimol S., Cline M. J. Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia. Proc. Natl. Acad. Sci. USA 1989; 86: 6783–6787
  • Ahuja H. G., Bar-Eli M., Clarke P., Snyder D., Foreman S., Goldman J., Cline M. J. p53 gene alterations in blast crisis of chronic myelogenous leukemia. Cancer Cells 1989; 7: 117–120
  • Kelman Z., Prokocimer M., Peller S., Kahn Y., Rechavi G., Manor Y., Cohen A., Rotter V. Rearrangements of the p53 gene in Philadelphia chromosome positive chronic myelocytic leukemia. Blood 1989; 74: 2318–2324
  • Marshal R., Shtalrid M., Talpaz M., Kantarjian H., Smith L., Beran M., Cork A., Trujillo J., Gutterman J., Deisseroth A. Rearrangement and expression of p53 in the chronic phase and blast crisis of chronic myelogenous leukemia. Blood 1990; 75: 180–189
  • Ahuja H., Bar-Eli M., Arlin Z., Advani S., Allen S. L., Goldman J., Snyder D., Foti A., Cline M. J. The spectrum of molecular alterations in the chronic myelocytic leukemia. J. Clinical Investigation 1991; 87: 2042–47
  • Finlay C. A., Hinds P. W., Levine A. J. The p53 proto-oncogene can act as a suppressor of transformation. Cell 1989; 57: 1083–1093
  • Baker S. J., Fearon E. R., Nigro J. M., Hamilton S. R., Preisinger A. C., Jessup J. M., VanTuinen P., Ledbetter D. H., Barker D. F., Nakamura Y., White R., Vogelstein B. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 1989; 244: 217–220
  • Takahashi T., Nau M. M., Chiba I., Birrer M. J., Rosenberg R. K., Vinocour M., Levitt M., Pass H., Gazdar A. F., Minna J. D. p53: A frequent target for genetic abnormalities in lung cancer. Science 1989; 246: 491–494
  • Nigro J. M., Baker S. J., Preisinger A. C., Jessup J. M., Hostetter R., Cleary K., Bigner S. H., Davidson N., Baylin S., Deville P., Glover T., Collins F. S., Weston A., Modali R., Harris C. C., Vogelstein B. Mutations in the p53 gene occur in diverse human tumor types. Nature 1989; 342: 705–708
  • Foti A., Ahuja H. G., Allen S. L., Koduru P., Shuster M. W., Schulman P, Eli M., Cline M. J. Correlation between molecular and clinical events in the evolution of chronic myelocytic leukemia to blast crisis. Blood 1991; 77: 2441–44
  • Gessler M., Poustka A., Cavanee W., et al. Homozygous deletion in Wilms' tumours of a zinc- finger gene identified by chromosome jumping. Nature 1989; 343: 774–8
  • Goddard A. D., Balakier H., Canton M., Dunn J., Squire J., Reyes E., Becker A., Phillips R. A., Gallie B. L. Infrequent genomic rearrangement and normal expression of the putative RBI gene in retinoblastoma tumors. Mol. and Cell. Biol. 1988; 8: 2082–2088
  • Friend S. H., Bernards R., Rogelj S., Weinberg R. A., Rapaport J. M., Albert D. M., Dryja T. P. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 1986; 323: 643–46
  • Lee W. H., Bookstein R., Hong F., Young L. J., Shew J. Y., Lee E. Y. Human retinoblastoma susceptibility gene: cloning, identification, and sequence. Science 1987; 235: 1394–1399
  • Fung Y. K., Murphree A. L., Ang A., Qian J., Hinrichs S. H., Benedict W. F. Structural evidence for the authenticity of the human retinoblastoma gene. Science 1987; 236: 1657–61
  • Bookstein R., Lee E. Y., To H., Young L. J., Sery T. W., Hayes R. G, Friedmann T., Lee W. H. Human retinoblastoma susceptibility gene: genomic organization and analysis of heterozygous intragenic deletion mutants. Proc. Natl. Acad. Sci. (USA) 1988; 85: 2210–2214
  • Ahuja H., Jat P. S., Bar-Eli M., Foti A., Cline M. J. Abnormalities of the retinoblastoma gene in the pathogenesis of acute leukemia. Blood 1991; 78: 3259–3268
  • Huang H. J., Yee J. K., Shew J. Y., Chen P. L., Bookstein R., Friedmann T., Lee E. Y., Lee W. H. Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells. Science 1988; 242: 1563–66

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