Expression of Diphtheria Toxin A-Chain in Mature B-Cells: A Potential Approach to Therapy of B-Lymphoid Malignancy

References

• Maxwell I. H., Maxwell F., Glode L. M. Regulated expression of a diphtheria toxin A-chain gene transfected into human cells: possible strategy for inducing cancer cell suicide. Cancer Res. 1986; 46: 4660–4664
   PubMed Web of Science ®Google Scholar
• Palmiter R. D., Behringer R. R., Quaife C. J., Maxwell F., Maxwell I. H., Brinster R. L. Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene. Cell 1987; 50: 435–443
   PubMed Web of Science ®Google Scholar
• Breitman M. L., Clapoff S., Rossant J., Tsui L. C., Glode L. M., Maxwell I. H., Bernstein A. Genetic ablation: programmed lineage suicide by tissue-specific expression of the diphtheria toxin A gene in transgenic mice. Science 1987; 238: 1563–1565
   PubMed Web of Science ®Google Scholar
• Yamaizumi M., Mekada E., Uchida T., Okada Y. One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell 1978; 15: 245–250
   PubMed Web of Science ®Google Scholar
• Behringer R. R., Mathews L. S., Palmiter R. D., Brinster R. L. Dwarf mice produced by genetic ablation of growth hormone-expressing cells. Genes and Development 1988; 2: 453–461
   PubMed Web of Science ®Google Scholar
• Kaur S., Key B., Stock J., McNeish J. D., Akeson R., Potter S. S. Targeted ablation of a-crystallin-synthesizing cells produces lens-deficient eyes in transgenic mice. Development 1989; 105: 613–619
   PubMed Web of Science ®Google Scholar
• Maxwell I. H., Glode L. M., Maxwell F. Expression of the diphtheria toxin A-chain coding sequence under the control of promoters and enhancers from immunoglobulin genes as a means of directing toxicity to B-lymphoid cells. Cancer Res. 1991; 51: 4299–4304
   PubMed Web of Science ®Google Scholar
• Maniatis T., Fritsch E. F., Sambrook J. Molecular Cloning. Cold Spring Harbor Laboratory. 1982
   Google Scholar
• Hendricks M. B., Banker M. J., McLaughlin M. A high efficiency vector for expression of foreign genes in myeloma cells. Gene 1988; 64: 43–51
   PubMed Web of Science ®Google Scholar
• Gillies S. D., Morrison S. L., Oi V. T., Tonegawa S. A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell 1983; 33: 717–728
   PubMed Web of Science ®Google Scholar
• Maxwell I. H., Harrison G. S., Wood W. M., Maxwell F. A DNA cassette containing a trimerized SV40 polyadenylation signal which efficiently blocks spurious plasmid-initiated transcription in transfected mammalian cells. Bio Techniques 1989; 7: 276–280
   PubMedGoogle Scholar
• Picard D., Schaffner W. A lymphocyte-specific enhancer in the mouse immunoglobulin kappa gene. Nature 1984; 307: 80–82
   PubMed Web of Science ®Google Scholar
• Queen C., Foster J., Stauber C., Stafford J. Cell-type specific regulation of a kappa immunoglobulin gene by promoter and enhancer elements. Immunol, Rev. 1986; 89: 49–68
   PubMed Web of Science ®Google Scholar
• de Wet J. R., Wood K. V., DeLuca M., Helinski D. R., Subramani S. Firefly luciferase gene: structure and expression in mammalian cells. Mol. Cell. Biol 1987; 7: 725–737
   PubMed Web of Science ®Google Scholar
• Ma J., Ptashne M. Deletion analysis of GAL4 defines two transcriptional activating segments. Cell 1987; 48: 847–853
   PubMed Web of Science ®Google Scholar
• Kakidani H., Ptashne M. GAL4 activates gene expression in mammalian cells. Cell 1988; 52: 161–167
   PubMed Web of Science ®Google Scholar
• Nordeen S. K. Luciferase reporter gene vectors for analysis of promoters and enhancers. Bio Techniques 1988; 6: 454–457
   PubMed Web of Science ®Google Scholar
• Paige C. J., Limeade P. W., Ralph P. Murine B cell leukemia line with inducible surface immunoglobulin expression. J. Immunol 1978; 121: 641–647
   PubMed Web of Science ®Google Scholar
• Kim K. J., Kanellopoulos-Langevin C., Merwin R. M., Sachs D. H., Asofsky R. Establishment and characterization of Balb/c lymphoma lines with B-cell properties. J. Immunol. 1979; 122: 549–554
   PubMed Web of Science ®Google Scholar
• Maxwell I. H., Maxwell F. Electroporation of mammalian cells with a firefly luciferase expression plasmid: Kinetics of transient expression differ markedly among cell types. DNA 1988; 7: 557–562
   PubMedGoogle Scholar
• Nelson K. J., Mather E. L., Perry R. P. Lipopolysaccharide-induced transcription of the kappa immunoglobulin locus occurs on both alleles and is independent of methylation status. Nucl. Acids Res. 1984; 12: 1911–1923
   PubMed Web of Science ®Google Scholar
• Wall R., Briskin M., Carter C., Govan H., Taylor A., Kincade P. A labile inhibitor blocks immunoglobulin kappa-light-chain-gene transcription in a pre-B leukemic cell line. Proc. Natl. Acad. Sci, USA 1986; 83: 295–298
   PubMed Web of Science ®Google Scholar
• Lenardo M., Pierce J. W., Baltimore D. Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility. Science 1987; 236: 1573–1577
   PubMed Web of Science ®Google Scholar
• Meyer K., Neuberger M. S. The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region. EMBO. J. 1989; 8: 1959–1964
   PubMed Web of Science ®Google Scholar
• Briskin M., Kuwabara M. D., Sigman D. S., Wall R. Induction of kappa transcription by interferon-gamma without activation of NF-kB. Science 1988; 242: 1036–1037
   PubMed Web of Science ®Google Scholar
• Shirakawa F., Chedid M., Suttles J., Pollok B. A., Mizel S. B. Interleukin 1 and cyclic AMP induce kappa immunoglobulin light-chain expression via activation of an NF-kB-like DNA-bindingprotein. Mol. Cell. Biol. 1989; 9: 959–964
   PubMed Web of Science ®Google Scholar
• Pierce J. W., Lenardo M., Baltimore D. Oligonucleotide that binds nuclear factor NF-kB acts as a lymphoid-specific and inducible enhancer element. Proc. Natl. Acad. Sci. USA 1988; 85: 1482–1486
   PubMed Web of Science ®Google Scholar