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Leukemia & Lymphoma Volume 7, 1992 - Issue 1-2
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Original Article

Recombinant Alpha 2B Interferon in Combination with Oral Chemotherapy in Late Chronic Phase Chronic Myeloid Leukaemia

F. J. Giles Division of Medical Oncology, University of North Carolina, Chapel Hill, North Carolina, USA
,
R. Aitchison Department of Haematology, The Royal London Hospital, London, UK
,
D. Syndercombe-Court Department of Haematology, The Royal London Hospital, London, UK
,
S. Schey Department of Haematology, Guy's Hospital, London, UK
&
A. C. Newland Department of Haematology, The Royal London Hospital, London, UK
Pages 99-102 | Received 01 Oct 1991, Published online: 01 Jul 2009

References

  • Goldman J. M., Perley J. F., Jones L., et al. Bone marrow transplantation for patients with chronic myeloid leukaemia. N. Engl. J. Med 1986; 314: 202–20
  • Talpaz M., Kantarjian H., Kurzrock R., et al. Update on therapeutic options for chronic myelogenous leukaemia. Sent. Haematol. 1990; 27(Supp. 4)31–6
  • Talpaz M., Kantarjian H., Kurzrock R., et al. Interferon-alpha produces sustained cytogenetic responses in Chronic Myelogenous Leukemia. Ann. Intern. Med 1991; 114: 532–38
  • Ozer H., Dear K., Testa J., et al. Prolonged administration of subcutaneous alpha-interferon induces major clinical and complete cytogenetic remissions in untreated Philadelphia positive chronic myelogenous leukemia. Proc. ASCO. 1990; 203a
  • Alimena G., Morra E., Lazzarino M., et al. Interferon alpha-2b as therapy for Ph1-positive chronic myelogenous leukaemia: a study of 82 patients treated with intermittent or daily administration. Blood 1988; 72: 642–47
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  • Guilhot F., Dreyfus B., Brizard A., et al. Cytogenetic remissions in chronic myelogenous leukemia using interferon alpha 2a and hydroxyurea with or without low dose cytosine arabinoside. Leukemia and Lymphoma. 1991, in press
  • Talpaz M., Kantarjian H., Kurzrock R., et al. Therapy of chronic myelogenous leukaemia: chemotherapy and interferons. Semin. Haematol 1988; 25(1)62–73
  • Cunningham I., Gee T., Dowling M., et al. Results of treatment of Ph1 + chronic myelogenous leukaemia with an intensive treatment regimen (L2 protocol). Blood 1979; 53: 375–395
  • Cox D. R., Oakes D. Analysis of survival data. Chapman and Hall, London 1984; 112–139
  • Aitchison R., McSweeney E., Butler L., et al. Cytogenetic and breakpoint cluster region changes in Chronic Myelogenous Leukaemia treated with low dose alpha-interferon. Eur. J. Cancer 1991, in press
  • Giles F. J., Singer C. R. J., Gray A., et al. Alpha-interferon therapy for essential thrombocythaemia. Lancet 1988; 2: 70–2

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