12
Views
26
CrossRef citations to date
0
Altmetric
Original Article

Serum Interleukin-6 Levels in Patients with Thrombocytosis

, , &
Pages 235-241 | Received 18 Apr 1992, Published online: 01 Jul 2009

References

  • Bruno E., Hoffman R. Effect of interleukin 6 on in vitro human megakaryocytopoiesis: its interaction with other cytokines. Experimental Hematology 1989; 17: 1038–1043
  • Ishibashi T., Kimura H., Shikama Y., Uchida T., Kariyone S., Hirano T., Kishimoto T., Takatsuki F., Akiyama Y. Interleukin-6 is a potent thrombopoietic factor in vivo in mice. Blood 1989; 74: 1241–1244
  • Asano S., Okano A., Ozawa K., Nakahata T., Ishibashi T., Koike H., Kimura H., Tanioka A., Shibuya T., Hirano T., Kishimoto T., Takaku F., Akiyama Y. In vivo effects of recombinant human interleukin-6 in primates: stimulated production of platelets. Blood 1990; 75: 1602–1605
  • Kishimoto T. The biology of interleukin-6. Blood 1989; 74: 1–10
  • Heinrich P. C., Castell J. V., Andus T. Interleukin-6 and the acute phase response. Biochemical Journal 1990; 265: 621–636
  • Sehgal P. B. Interleukin-6: A regulator of plasma protein gene expression in hepatic and non-hepatic tissues. Molecular Biology and Medicine 1990; 7: 117–130
  • Sims R. B., Gewirtz A. M. Human megakaryocytopoiesis. Annual Review of Medicine 1989; 40: 213–224
  • Burstein S. A., Harker L. A. Control of platelet production. Clinics in Haematology 1983; 12: 3–22
  • Williams W. J. Thrombocytosis. Hematology, W. J. Williams, E. Beutler, A. J. Erslev, M. A. Lichtman. McGraw-Hill, New York 1990; 1403–1406
  • Kanz L., Hollen C. W., Friese P., Burstein S. A. Analysis of megakaryocyte ploidy in patients with thrombocytosis. International Journal of Cell Cloning 1990; 8: 299–306
  • Hoffman R. Regulation of megakaryocytopoiesis. Blood 1989; 74: 1196–1212
  • Hollen C. W., Henthorn J., Koziol J., Burstein S. A. Elevated serum interleukin-6 levels in patients with reactive thrombocytosis. British Journal of Haematology 1991; 79: 286–290
  • Brakenhoff J. P. J., Degroot E. R., Evers R. F., Pannekoek H., Aarden L. A. Molecular cloning and expression of hybridoma growth factor in Escherichia Coli. Journal of Immunology 1987; 139: 4116–4121
  • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunologic Methods 1983; 65: 55–63
  • Hansen M. B., Nielsen S. E., Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. Journal of Immunologic Methods 1989; 119: 203–210
  • Studier F. W., Rosenberg A. H., Dunn J. J., Dubendorff J. W. Use of T7 RNA polymerase to direct expression of cloned genes. Methods in Enzymolog, Volume 185. Gene Expression Technology, D. V. Goeddel. Academic Press, San Diego 1990; 60–89
  • McDonald T. P. Regulation of megakaryocytopoiesis by thrombopoietin. Annals of the New York Academy of Sciences 1987; 509: 1–24
  • Abe T., Fuhrer J. P., Bregman M. D., Kuramoto A., Murphy M. J. Factors regulating megakaryocytopoiesis and platelet formation. Advances in Experimental Medicine and Biology 1988; 241: 183–190
  • Metcalf D., Hilton D., Nicola N. A. Leukemia inhibitory factor can potentiate murine megakaryocyte production in vitro. Blood 1991; 77: 2150–2153
  • De Alarcon P. A. Megakaryocyte colony-stimulating factor (Mk-CSF) Its physiologic significance. Blood Cells 1989; 15: 173–185
  • Paul S. R., Bennet F., Calvetti J. A., Kelleher K, Wood C. R., O'Hara R.M., Leary A. C., Sibley B., Clark S. C., Williams D. A., Yang Y. C. (1978) Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. Proceedings of the National Academy of Sciences of the USA 1990; 87:7512–7516. 1990
  • Imai T., Koike K., Kubo T., Kikuchi T., Amano Y., Takagi M., Okumura N., Nakahata T. Interleukin-6 supports human megakaryocytic proliferation and differentiation in vitro. Blood. 1991; 78: 1969–1974
  • Bruno E., Briddell R. A., Cooper R. J., Hoffman R. Effects of recombinant interleukin 11 on human megakaryocyte progenitor cells. Experimental Hematology 1991; 19: 378–381
  • Metcalf D., Nicola N. A., Gearing D. P. Effects of injected leukemia inhibitory factor on hematopoietic and other tissues in mice. Blood 1990; 76: 50–56
  • Kimura H., Ishibashi T., Shikama Y., Okano A., Akiyama Y., Uchida T., Maruyama Y. Interleukin-1B (IL-1β) induces thrombocytosis in mice: possible implication of IL-6. Blood 1990; 76: 2493–2500
  • Hilton D. J., Gough N. M. Leukemia inhibitory factor: A biological perspective. Journal of Cellular Biochemistry 1991; 46: 21–26
  • Leser H. G., Gross V., Scheibenbogen C., Heinisch A., Salm R., Lausen M., Ruckauer K., Andreesen R., Farthmann E. H., Scholmerich J. Elevation of serum interleukin-6 concentration precedes acute-phase response and reflects severity in acute pancreatis. Gastroenterology 1991; 101: 782–785
  • Hovdenes J., Kvien T. K., Hovdenes A. B. IL-6 in synovial fluids, plasma and supernatants from cultured cells of patients with rheumatoid arthritis and other inflammatory arthritides. Scandanavian Journal od Rheumatology 1990; 19: 177–182
  • Houssiau F. A., Devogelaer J.-P., Van Damme J., De Deuxchaisnes C. N., Van Snick J. Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides. Arthritis and Rheumatism 1988; 31: 784–788
  • Helfgott D. C., Tatter S. B., Santhanam U., Clarick R. H., Bhardwaj N., May L. T., Sehgal P. B. Multiple forms of IFN-β2/IL-6 in serum and body fluids during acute bacterial infection. Journal of Immunology 1989; 142: 948–953
  • Fong Y., Moldawer L. L., Marano M., Wei H., Tatter S. B., Clarick R. H., Santhanam U., Sherris D., May L. T., Sehgal P. B., Lowry S. F. Endotoxemia elicits increased circulating β2-IFN/IL-6 in man. Journal of Immunology 1989; 142: 2321–2324
  • Hack C. E., De Groot E. R., Felt-Bersma R. J. F., Nuijens J H., Strack Van Schijndel R. J. M. S., Eerenberg-Belmer A. J., Thijs L. G., Aarden L. A. Increased plasma levels of interleukin-6 in sepsis. Blood 1989; 74: 1704–1710
  • Van Damme J., Schaafsma M. R., Fibbe W. E., Falkenburg J. H. F., Opdenakker G., Billiau A. Simultaneous production of interleukin-6, interferon-β and colony-stimulating activity by fibroblasts after viral and bacterial infection. European Journal of Immunology 1989; 19: 163–168
  • De Benedetti F., Massa M., Robbioni P., Ravelli A., Burgio G. R., Martini A. Correlation of serum interleukin-6 levels with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis. Arthritis and Rheumatism 1991; 34: 1158–1163
  • Guo Y., Dickerson C., Chrest F. J., Adler W. H., Munster A. M., Winchurch R. A. Increased levels of circulating interleukin-6 in burn patients. Clinical Immunology and Immunopathology 1990; 54: 361–371
  • Cruickshank A. M., Fraser W. D., Burns H. J. G., Van Damme J., Shenkin A. Response of serum interleukin-6 in patients undergoing elective surgery of varying severity. Clinical Science 1990; 79: 161–165
  • Ertel W., Faist E., Nestle C., Hueltner L., Storck M., Schildberg F. W. Kinetics of interleukin-2 and interleukin-6 sysnthesis following major mechanical trauma. Journal of Surgical Research 1990; 48: 622–628
  • Shenkin A., Fraser W. D., Series J., Winstanley F. P., McCartney A. C., Burns H. J. G., Van Damme J. The serum interleukin 6 response to elective surgery. Lymphokine Research 1989; 8: 123–127
  • Tabibzadedh S. S., Poubouridis D., May L. T., Sehgal P. B. Interleukin-6 immunoreactivity in human tumors. Americal Journal of Pathology 1989; 135: 427–433
  • Biondi A., Rossi V., Bassan R., Barbui T., Bettoni S., Sironi M., Mantovani A., Rambaldi A. Constitutive expression of the interleukin-6 gene in chronic lymphocytic leukemia. Blood 1989; 73: 1279–1284
  • Freeman G. J., Freedman A. S., Rabinowe S. N., Segil J. M., Horowitz J., Rosen K., Whitman J. F., Nadler L. M. Interleukin-6 gene expression in normal and neoplastic B cells. Journal of Clinical Investigations 1989; 83: 1512–1518
  • Utsumi K., Takai Y., Tada T., Ohzeki S., Fujiwara H., Hamoaka T. Enhanced production of IL-6 in tumor-bearing mice and determination of cells responsible for its augmented production. Journal of Immunology 1990; 145: 397–403
  • McIntosh J. K., Jablons D. M., MulÉ J. J., Nordan R. P., Rudikoff S., Lotze M. T., Rosenberg S. A. In vivo induction of IL-6 by administration of exogenous cytokines and detection of de novo serum levels of IL-6 in tumor-bearing mice. Journal of Immunology 1989; 143: 162–167
  • Berek J. S., Chung C., Kaldi K., Watson J. M., Knox R. M., Martinez-Maza O. Serum interleukin-6 levels correlate with disease status in patients with epithelial ovarian cancer. American Journal of Obstetrics and Gynecology 1991; 164: 1038–1043
  • Nachbaur D. M., Herold M., Maneschg A., Huber H. Serum levels of interleukin-6 in multiple myeloma and other hematological disorders: correlation with disease activity and other prognostic parameters. Annals of Hematology 1991; 62: 54–58
  • Klein B., Wijdenes J., Zhang X. G., Jourdan M., Boiron J. M., Brochier J., Liautard J., Merlin M., Clement C., Morel-Fournier B., Lu Z. Y., Mannoni P., Sany J., Bataille R. Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia. Blood 1991; 78: 1198–1204
  • Mei R, Burstein S. A. Megakaryocytic maturation in murine long-term bone marrow culture: Role of interleukin-6. Blood 1991; 78: 1438–1447
  • Sonne O., Davidsen O., Moller B. K., Munck Petersen C. Cellular targets and receptors for interleukin-6. I. In vivo and in vitro uptake of IL-6 in liver and hepatocytes. European Journal of Clinical Investigations 1990; 20: 366–376
  • Long M. W. Regulation of human megakaryocytopoiesis. Annals of the New York Academy of Sciences 1989; 554: 192–205
  • George J. N., Aster R. H. Thrombocytopenia due to enhanced platelet destruction by nonimmunologic mechanisims. Hematology, W. J. Williams, E. Beutler, A. J. Erslev, M. A. Lichtman. McGraw- Hill, New York 1990; 1351–1370

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.